Avaliação de cimento endodôntico resinoso experimental contendo nanopartículas core-shell Ag@SiO2

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Avaliação de cimento endodôntico resinoso experimental contendo nanopartículas core-shell Ag@SiO2

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Physicochemical and biological evaluation of a triazine-methacrylate monomer into a dental resin

Objectives: This study aimed to (1) formulate blend resins with 2.5 or 5 wt.% of the methacrylate monomer 1,3,5- triacryloylhexahydro-1,3,5-triazine (TAT), and (2) to evaluate the blend resins regarding the physicochemical and biological properties. Methods: The base resin was formulated mixing 60 wt.% of bisphenol A glycol dimethacrylate and 40 wt.% of triethylene glycol dimethacrylate with photoinitiator/co/initiator system. TAT was added at 2.5 (G2.5%) or 5 (G5%) wt.%, and a group without TAT was used as control (Gctrl). The resins were analyzed for degree of con version (DC), Knoop hardness (KHN), softening in solvent (ΔKHN), ultimate tensile strength (UTS), contact angle, surface free energy (SFE), antibacterial activity against Streptococcus mutans biofilm formation, and cytotoxicity against human keratinocytes. Results: There was no difference for the DC (p = 0.676). The addition of TAT at 5 wt.% induced higher KHN (p0.05), and G5% induced lower cell viability (p<0.05). Conclusions: The addition of 2.5 wt.% of TAT is suitable for conveying antibacterial activity for dental resins without changing the physicochemical properties or impairing the cytotoxic effect. Clinical relevance: Methacrylate monomers that decrease bacterial viability and copolymerize with the resin matrix are exciting approaches to developing therapeutic materials. TAT showed promising properties to may hamper and prevent carious lesions when incorporated into dental materials. Further evaluations with higher cariogenic challenges will be carried to analyze the formulated materials