Diabetes insípida central en un perro

Se describe un caso de diabetes insípida central [DIC] en un perro. Este caso es particularmente interesante pues se observan modificaciones electrolíticas poco habituales. En la discusión se comenta la posible etiología del proceso, los hallazgos analíticos y el procedimiento de diagnóstico elegido.It is described a case of canine central diabetes insipidus particularly interesting because is presented with very un usual electrolytic abnormalities. The etiology, the atypical electrolytic levels observed and the diagnostic method used are discussed

Manual de prácticas de hamotología veterinaria

Proyecto que se realiza en el Departamento de Medicina Veterinaria de la Facultad de Veterinaria de la Universidad de León. Estan implicados 5 profesores del Departamento. Se trata de elaborar un documento para poner a disposición de los alumnos con el fin de que puedan seguir el desarrollo de las sesiones prácticas de forma estructurada y ordenada. Se ha recogido la información que cada profesor aportaba a los alumnos individualmente, se ha puesto por escrito, se han unificado criterios y se ha puesto a disposición de los alumnos un único ejemplar de uso sencillo. Todo ello va encaminado a favorecer el aprendizaje de los alumnos, potenciar la eficacia de las prácticas, a la adquisición por parte de los alumnos de las competencias de la titulación y fomentar el trabajo en equipo. Se ha elaborado un documento en el que se recogen todas las técnicas implicadas en el desarrollo de las prácticas utilizando el material habitual del laboratorio, microscopios y diversa bibliografía así como el material informático necesario para el procesamiento y almacenaje de la información. No esta publicado.Junta de Castilla y León. Dirección General de Universidades e Investigación. Monasterio de Ntra. Sra. del Prado. Autovia Puente Colgante s/n. 47071 Valladolid. Teléfono: 983-41.18.87Castilla y LeónES

Renal handling of calcium and phosphorus in experimental renal hyperparathyroidism in dogs

Twenty-four hour urinary excretion, fractional excretion and the filtered load of calcium and phosphorus were monitored as hyperparathyroidism evolved in a model of progressive canine renal failure. Thirteen beagles of both sexes aged four and a half months were used. Nine of them were subjected to a renal damaging schedule (neomycine, 60 mg/kg/48 h, IM, 32 weeks) in order to induce chronic renal failure leading to secondary hyperparathyroidism (2HPT group). The remaining four were kept as the control group. The experiment was conducted over 32 weeks. Blood and 24 h urine were collected every four weeks. Calcium, phosphorus and creatinine were analyzed. Plasma parathormone and calcitonin were determined at weeks 0, 12, 24 and 32. The level of renal function in the 2HPT animals was reduced to 25% of that of the controls (endogenous creatinine clearance was 0.45$\pm$ 0.22 mL/min/kg as opposed to 1.81 $\pm$ 0.54 mL/min/kg). Hyperparathyroidism was confirmed by a progressive increase in the levels of the parathyroid hormone. Calcitonin levels were not modified. A tendency to hypocalcaemia was observed, reaching statistically significant levels from the twenty-eighth week of the study, when hyperphosphataemia also became significant. Daily urinary excretion of calcium and phosphorus remained at values considered normal throughout the experiment with no alteration imputable to the impaired renal function. This is explained by the decrease in the filtered load of these elements (in both cases statistically significant from the 24th week on) being associated with an increase in their fractional excretion. Thus, calcium and phosphorus urinary excretion values could be maintained in a normal range up to the end of the experiment, showing that renal calcium handling in dogs with experimentally induced renal failure seems to differ from that observed in human patients