Revista da Sociedade Brasileira de Medicina Tropical

P. 546-549,set-out.O episódio reacional tipo 1 ou reação reversa é ocorrência inflamatória aguda que atinge a pele e nervos periféricos, encontrada em até 30% dos pacientes com hanseníase, sendo causa comum de incapacidade física. Fatores de risco associados incluem uso de poliquimioterapia e infecções virais. Neste estudo, foram avaliados 620 pacientes com hanseníase. Reação reversa foi diagnosticada em 121 (19,5%) casos, sendo mais freqüente nos indivíduos borderlines (48%). Início da poliquimioterapia foi considerado fator de risco para reação reversa, com 52% dos casos apresentando o primeiro episódio neste momento. Neurite foi documentada em 73% dos casos. A presença de vírus B ou C da hepatite foi documentada em 9% de 55 pacientes com reação reversa e em nenhum dos 57 pacientes sem reação (p = 0, 026; teste exato de Fisher), sugerindo possível papel destes agentes como fatores de risco para desenvolvimento de reação reversa na hanseníase.Uberab

International Journal of Dermatology

Texto completo: acesso restrito. p. 295-296Salvado

Anais Brasileiros de Dermatologia

p. 473-475Congenital Hypertrichosis Lanugionsa is a rare autosomal dominant genetic disorder, with fewer than 50 cases reported in the literature. It is characterized by excessive lanugo hair, sparing only the mucous membranes, palms and soles. It may be associated with other organic abnormalities and should form part of the dermatologist's current knowledge. We discuss some aspects of the syndrome in question arising from the case report of a 2-year-old female patient, black, with classic clinical presentation, with no other associated congenital abnormalities.Rio de janeir

Anais Brasileiros de Dermatologia

Restrito: p. 473-475Congenital Hypertrichosis Lanugionsa is a rare autosomal dominant genetic disorder, with fewer than 50 cases reported in the literature. It is characterized by excessive lanugo hair, sparing only the mucous membranes, palms and soles. It may be associated with other organic abnormalities and should form part of the dermatologist's current knowledge. We discuss some aspects of the syndrome in question arising from the case report of a 2-year-old female patient, black, with classic clinical presentation, with no other associated congenital abnormalities

Anais Brasileiros de Dermatologia

p.144-147Psoriasis affects 0.12% to 0.71% of all chil dren. Erythrodermic pso ria sis is an uncom mon but serious disor der, occur ring in less than 1.5% of cases. Tumor necro sis fac tor-alpha bloc kers (TNF-) are a new class of drugs used to treat mode ra te to seve re pso ria sis refrac tory to con ven tio nal the ra pies. Etanercept is a TNFrecep tor fusion pro tein, appro ved by the FDA for trea ting juve ni le rheu ma toid arth ri tis. We pre sent the case of a 7-year-old suf fe ring from pla que pso ria sis since 8 months old which evol ved into eryth ro der ma refrac tory to cyclos po ri ne and metho tre xa te. Patient res pon ded excel lently to eta ner cept, with no adver se side effects.Rio de Janeir

Do you know this syndrome? Você conhece esta síndrome?

Congenital Hypertrichosis Lanugionsa is a rare autosomal dominant genetic disorder, with fewer than 50 cases reported in the literature. It is characterized by excessive lanugo hair, sparing only the mucous membranes, palms and soles. It may be associated with other organic abnormalities and should form part of the dermatologist's current knowledge. We discuss some aspects of the syndrome in question arising from the case report of a 2-year-old female patient, black, with classic clinical presentation, with no other associated congenital abnormalities.<br>A hipertricose Lanugionsa Cong&#234;nita &#233; uma desordem gen&#233;tica rara, autoss&#244;mica dominante, com menos de 50 casos descritos na literatura. &#201; caracterizada por p&#234;lo lanugo excessivo, poupando apenas membranas mucosas, palmas e plantas. Pode estar associada a outras anormalidades org&#226;nicas, devendo ser de conhecimento do dermatologista. Discutiremos aspectos da s&#237;ndrome em quest&#227;o a partir do relato de caso de uma paciente do sexo feminino, negra, 02 anos, com apresenta&#231;&#227;o cl&#237;nica cl&#225;ssica, sem outras anormalidades cong&#234;nitas associadas

Anais Brasileiros de Dermatologia

p. 185-198Inherited epidermolysis bullosa (EB) is a heterogeneous group of genetic disorders that present with skin and, in some cases, mucosal fragility, predisposing patients to the development of blisters and/or erosions after minimal trauma or friction. Children with a recurrent history of these kinds of lesions or neonates that present them in the absence of another reasonable explanation should be investigated. Diagnosis must be based on clinical and histopathological findings. To date, management of inherited EB basically consists in avoiding traumas that trigger lesions, as well as preventing infection and facilitating healing of the wounds with the systematic use of bandages