2,559 research outputs found

    Evaluation of star gyro torquing final report

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    Electrostatic gyroscope torquin

    Analysis and preliminary design of optical sensors for propulsion control

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    A fiber-optic sensor concept screening study was performed. Twenty sensor subsystems were identified and evaluated. Two concepts selected for further study were the Fabry-Perot fiber-optic temperature sensor and the pulse-width-modulated phosphorescent temperature sensor. Various designs suitable for a Fabry-Perot temperature sensor to be used as a remote fiber-optic transducer were investigated. As a result, a particular design was selected and constructed. Tests on this device show that spectral peaks are produced from visible white light, and the change in wavelength of the spectral peaks produced by a change in temperature is consistent with theory and is 36 nm/C for the first order peak. A literature search to determine a suitable phosphor for implementing the pulse-width-modulated fiber optic temperature sensor was conducted. This search indicated that such a device could be made to function for temperatures up to approximately 200 C. Materials like ZnCdS and ZnSe activated with copper will be particularly applicable to temperature sensing in the cryogenic to room temperature region. While this sensing concept is probably not applicable to jet engines, the simplicity and potential reliability make the concept highly desirable for other applications

    Traumatic Gastritis Involving the Spleen

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    Occasionally there comes to the attention of the veterinarian an animal with a pathological condition which is very difficult to diagnose. Such was the case of an 8-year-old Holstein cow that was presented for treatment at the Stange Memorial Clinic on January 11, 1945

    Regions of beta 2 and beta 4 responsible for differences between the steady state dose-response relationships of the alpha 3 beta 2 and alpha 3 beta 4 neuronal nicotinic receptors

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    We constructed chimeras of the rat beta 2 and beta 4 neuronal nicotinic subunits to locate the regions that contribute to differences between the acetylcholine (ACh) dose-response relationships of the alpha 3 beta 2 and alpha 3 beta 4 receptors. Expressed in Xenopus oocytes, the alpha 3 beta 2 receptor displays an EC50 for ACh approximately 20-fold less than the EC50 of the alpha 3 beta 4 receptor. The apparent Hill slope (n(app)) of alpha 3 beta 2 is near one whereas the alpha 3 beta 4 receptor displays an n(app) near two. Substitutions within the first 120 residues convert the EC50 for ACh from one wild-type value to the other. Exchanging just beta 2:104-120 for the corresponding region of beta 4 shifts the EC50 of ACh dose-response relationship in the expected direction but does not completely convert the EC50 of the dose- response relationship from one wild-type value to the other. However, substitutions in the beta 2:104-120 region do account for the relative sensitivity of the alpha 3 beta 2 receptor to cytisine, tetramethylammonium, and ACh. The expression of beta 4-like (strong) cooperativity requires an extensive region of beta 4 (beta 4:1-301). Relatively short beta 2 substitutions (beta 2:104-120) can reduce cooperativity to beta 2-like values. The results suggest that amino acids within the first 120 residues of beta 2 and the corresponding region of beta 4 contribute to an agonist binding site that bridges the alpha and beta subunits in neuronal nicotinic receptors
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