Image3_Design and application of a point-of-care testing system for triple detection of SARS-CoV-2, influenza A, and influenza B.TIF

To mitigate the continued impact of SARS-CoV-2, influenza A, and influenza B viruses on human health, a smartphone-based point-of-care testing (POCT) system was designed to detect respiratory pathogens through a nucleic acid test. This compact, light-weight, highly automated, and universal system enables the differential diagnosis of SARS-CoV-2, influenza A, and influenza B in approximately 30 min in a single-tube reaction. Numerous hospitals and disease control and prevention center assessed the triple POCT system’s detection threshold, sensitivity, specificity, and stability, and have concluded that all the assessments were comparable to those of fluorescent quantitative polymerase chain reaction (PCR)-based testing. The triple POCT system is suitable as an onsite rapid-diagnosis device, as well as for pathogen screening at airports and customs.</p

Image5_Design and application of a point-of-care testing system for triple detection of SARS-CoV-2, influenza A, and influenza B.TIF

To mitigate the continued impact of SARS-CoV-2, influenza A, and influenza B viruses on human health, a smartphone-based point-of-care testing (POCT) system was designed to detect respiratory pathogens through a nucleic acid test. This compact, light-weight, highly automated, and universal system enables the differential diagnosis of SARS-CoV-2, influenza A, and influenza B in approximately 30 min in a single-tube reaction. Numerous hospitals and disease control and prevention center assessed the triple POCT system’s detection threshold, sensitivity, specificity, and stability, and have concluded that all the assessments were comparable to those of fluorescent quantitative polymerase chain reaction (PCR)-based testing. The triple POCT system is suitable as an onsite rapid-diagnosis device, as well as for pathogen screening at airports and customs.</p

Image2_Design and application of a point-of-care testing system for triple detection of SARS-CoV-2, influenza A, and influenza B.TIF

To mitigate the continued impact of SARS-CoV-2, influenza A, and influenza B viruses on human health, a smartphone-based point-of-care testing (POCT) system was designed to detect respiratory pathogens through a nucleic acid test. This compact, light-weight, highly automated, and universal system enables the differential diagnosis of SARS-CoV-2, influenza A, and influenza B in approximately 30 min in a single-tube reaction. Numerous hospitals and disease control and prevention center assessed the triple POCT system’s detection threshold, sensitivity, specificity, and stability, and have concluded that all the assessments were comparable to those of fluorescent quantitative polymerase chain reaction (PCR)-based testing. The triple POCT system is suitable as an onsite rapid-diagnosis device, as well as for pathogen screening at airports and customs.</p

Image1_Design and application of a point-of-care testing system for triple detection of SARS-CoV-2, influenza A, and influenza B.TIF

To mitigate the continued impact of SARS-CoV-2, influenza A, and influenza B viruses on human health, a smartphone-based point-of-care testing (POCT) system was designed to detect respiratory pathogens through a nucleic acid test. This compact, light-weight, highly automated, and universal system enables the differential diagnosis of SARS-CoV-2, influenza A, and influenza B in approximately 30 min in a single-tube reaction. Numerous hospitals and disease control and prevention center assessed the triple POCT system’s detection threshold, sensitivity, specificity, and stability, and have concluded that all the assessments were comparable to those of fluorescent quantitative polymerase chain reaction (PCR)-based testing. The triple POCT system is suitable as an onsite rapid-diagnosis device, as well as for pathogen screening at airports and customs.</p

Image4_Design and application of a point-of-care testing system for triple detection of SARS-CoV-2, influenza A, and influenza B.TIF

To mitigate the continued impact of SARS-CoV-2, influenza A, and influenza B viruses on human health, a smartphone-based point-of-care testing (POCT) system was designed to detect respiratory pathogens through a nucleic acid test. This compact, light-weight, highly automated, and universal system enables the differential diagnosis of SARS-CoV-2, influenza A, and influenza B in approximately 30 min in a single-tube reaction. Numerous hospitals and disease control and prevention center assessed the triple POCT system’s detection threshold, sensitivity, specificity, and stability, and have concluded that all the assessments were comparable to those of fluorescent quantitative polymerase chain reaction (PCR)-based testing. The triple POCT system is suitable as an onsite rapid-diagnosis device, as well as for pathogen screening at airports and customs.</p

The procedures of modified delta-shaped gastroduodenostomy before closing the common stab incision.

<p><b>a</b> Diagram showing that the stapler was positioned across the duodenum vertical to the long axis in the predetermined position and fired to transect the duodenum by rotating 90 degrees from back to front. <b>b</b> Intraoperative image showing that the stapler was positioned across the duodenum vertical to the long axis in the predetermined position and fired to transect the duodenum by rotating 90 degrees from back to front. <b>c</b> Diagram showing that the stomach was resected by successively transecting from the greater curvature to the lesser curvature with two staplers. <b>d</b> Intraoperative image showing that the stomach was resected by successively transecting from the greater curvature to the lesser curvature with two staplers. <b>e</b> Diagram showing that the stapler was positioned to join the posterior walls together. <b>f</b> Intraoperative image showing that the stapler was positioned to join the posterior walls together. <b>g</b> Diagram showing the V-shaped anastomosis on the posterior wall. <b>h</b> Intraoperative image showing the V-shaped anastomosis on the posterior wall.</p

Risk factors influencing complications after TLDG with modified DSG for GC.

<p>TLDG totally laparoscopic distal gastrectomy; DSG delta-shaped gastroduodenostomy; GC gastric cancer; CI, confidence interval; NS, nutritional support; BPT, blood products transfusion; LN, lymph node.</p

Surgical outcomes of patients undergoing TLDG with modified DSG for GC.

<p>LN, lymph node. DSG, delta-shaped gastroduodenostomy. TLDG, totally laparoscopic distal gastrectomy. GC gastric cancer.</p

The differences between the conventional delta-shaped gastroduodenostomy (DSG) and the modified DSG.

<p><b>a</b> Diagram showing that three sutures were added to each end of the common stab incision and the cutting edges of the stomach and duodenum to obtain an involution and pull in the conventional DSG. <b>b</b> Diagram showing the completed involution of the common stab incision using the instruments of the surgeon and assistant with the blind angle of the duodenum being pulled up into the stapler in the modified DSG. <b>c</b> Diagram showing the completed conventional DSG with two intersections of the gastroduodenal cutting edge and the common closed edge. <b>d</b> Diagram showing the completed modified DSG with only one intersection of the gastric cutting edge and the common closed edge. <b>e</b> Intraoperative image showing the completed involution of the common stab incision using the instruments of the surgeon and assistant with the blind angle of the duodenum being pulled up into the stapler in the modified DSG. <b>f</b> Intraoperative image showing the completed inverted T-shaped appearance of anastomosis in the modified DSG.</p

Trocar placements for totally laparoscopic distal gastrectomy.

<p>Trocar placements for totally laparoscopic distal gastrectomy.</p