High-temperature electrical and thermal transport properties of fully filled skutterudites RFe_(4)Sb_(12) (R = Ca, Sr, Ba, La, Ce, Pr, Nd, Eu, and Yb)

Fully filled skutterudites RFe_(4)Sb_(12) (R = Ca, Sr, Ba, La, Ce, Pr, Nd, Eu, and Yb) have been prepared and the high-temperature electrical and thermal transport properties are investigated systematically. Lattice constants of RFe_(4)Sb_(12) increase almost linearly with increasing the ionic radii of the fillers, while the lattice expansion in filled structure is weakly influenced by the filler valence charge states. Using simple charge counting, the hole concentration in RFe_(4)Sb_(12) with divalent fillers (R = Ca, Sr, Ba, Eu, and Yb) is much higher than that in RFe4Sb12 with trivalent fillers (R = La, Ce, Pr, and Nd), resulting in relatively high electrical conductivity and low Seebeck coefficient. It is also found that RFe_(4)Sb_(12) filled skutterudites having similar filler valence charge states exhibit comparable electrical conductivity and Seebeck coefficient, and the behavior of the temperature dependence, thereby leading to comparable power factor values in the temperature range from 300 to 800 K. All RFe_(4)Sb_(12) samples possess low lattice thermal conductivity. The correlation between the lattice thermal resistivity WL and ionic radii of the fillers is discussed and a good relationship of W_L ~ (r_(cage)−r_(ion))^3 is observed in lanthanide metal filled skutterudites. CeFe_(4)Sb_(12), PrFe_(4)Sb_(12), and NdFe_(4)Sb_(12) show the highest thermoelectric figure of merit around 0.87 at 750 K among all the filled skutterudites studied in this work

Persistent global power fluctuations near a dynamic transition in electroconvection

This is a study of the global fluctuations in power dissipation and light transmission through a liquid crystal just above the onset of electroconvection. The source of the fluctuations is found to be the creation and annihilation of defects. They are spatially uncorrelated and yet temporally correlated. The temporal correlation is seen to persist for extremely long times. There seems to be an especially close relation between defect creation/annihilat ion in electroconvection and thermal plumes in Rayleigh-B\'enard convection

Linguistic Structure Guided Context Modeling for Referring Image Segmentation

Referring image segmentation aims to predict the foreground mask of the object referred by a natural language sentence. Multimodal context of the sentence is crucial to distinguish the referent from the background. Existing methods either insufficiently or redundantly model the multimodal context. To tackle this problem, we propose a "gather-propagate-distribute" scheme to model multimodal context by cross-modal interaction and implement this scheme as a novel Linguistic Structure guided Context Modeling (LSCM) module. Our LSCM module builds a Dependency Parsing Tree suppressed Word Graph (DPT-WG) which guides all the words to include valid multimodal context of the sentence while excluding disturbing ones through three steps over the multimodal feature, i.e., gathering, constrained propagation and distributing. Extensive experiments on four benchmarks demonstrate that our method outperforms all the previous state-of-the-arts.Comment: Accepted by ECCV 2020. Code is available at https://github.com/spyflying/LSCM-Refse

Elliptical Galaxies with Emission Lines from the Sloan Digital Sky Survey

We present the results of 11 elliptical galaxies with strong nebular emission lines during our study of star formation history along the Hubble sequence. After removing the dilution from the underlying old stellar populations by use of stellar population synthesis model, we derive the accurate fluxes of all emission lines for these objects, which are later classified with emission line ratios into one Seyfert 2, six LINERs and four HII galaxies. We also identify one HII galaxy (A1216+04) as a hitherto unknown Wolf-Rayet galaxy from the presence of the Wolf-Rayet broad bump at 4650 \AA. We propose that the star-forming activities in elliptical galaxies are triggered by either galaxy-galaxy interaction or the merging of a small satellite/a massive star cluster, as already suggested by recent numerical simulations

Dementia-related adverse events in PARADIGM-HF and other trials in heart failure with reduced ejection fraction.

Aims: Inhibition of neprilysin, an enzyme degrading natriuretic and other vasoactive peptides, is beneficial in heart failure with reduced ejection fraction (HFrEF), as shown in PARADIGM-HF which compared the angiotensin receptor–neprilysin inhibitor (ARNI) sacubitril/valsartan with enalapril. As neprilysin is also one of many enzymes clearing amyloid-β peptides from the brain, there is a theoretical concern about the long-term effects of sacubitril/valsartan on cognition. Therefore, we have examined dementia-related adverse effects (AEs) in PARADIGM-HF and placed these findings in the context of other recently conducted HFrEF trials. Methods and results: In PARADIGM-HF, patients with symptomatic HFrEF were randomized to sacubitril/valsartan 97/103 mg b.i.d. or enalapril 10 mg b.i.d. in a 1:1 ratio. We systematically searched AE reports, coded using the Medical Dictionary for Regulatory Activities (MedDRA), using Standardized MedDRA Queries (SMQs) with ‘broad’ and ‘narrow’ preferred terms related to dementia. In PARADIGM-HF, 8399 patients aged 18–96 years were randomized and followed for a median of 2.25 years (up to 4.3 years). The narrow SMQ search identified 27 dementia-related AEs: 15 (0.36%) on enalapril and 12 (0.29%) on sacubitril/valsartan [hazard ratio (HR) 0.73, 95% confidence interval (CI) 0.33–1.59]. The broad search identified 97 (2.30%) and 104 (2.48%) AEs (HR 1.01, 95% CI 0.75–1.37), respectively. The rates of dementia-related AEs in both treatment groups in PARADIGM-HF were similar to those in three other recent trials in HFrEF. Conclusion: We found no evidence that sacubitril/valsartan, compared with enalapril, increased dementia-related AEs, although longer follow-up may be necessary to detect such a signal and more sensitive tools are needed to detect lesser degrees of cognitive impairment. Further studies to address this question are warranted

Overcoming Coulomb Interaction Improves Free-Charge Generation and Thermoelectric Properties for n-Doped Conjugated Polymers

Molecular doping of organic semiconductors creates Coulombically bound charge and counterion pairs through a charge-transfer process. However, their Coulomb interactions and strategies to mitigate their effects have been rarely addressed. Here, we report that the number of free charges and thermoelectric properties are greatly enhanced by overcoming the Coulomb interaction in an n-doped conjugated polymer. Poly(2,2'-bithiazolothienyl-4,4',10,10'-tetracarboxydiimide) (PDTzTI) and the benchmark N2200 are n-doped by tetrakis (dimethylamino) ethylene (TDAE) for thermoelectrics. Doped PDTzTI exhibits similar to 10 times higher free-charge density and 500 times higher conductivity than doped N2200, leading to a power factor of 7.6 mu W m(-1) K-2 and ZT of 0.01 at room temperature. Compared to N2200, PDTzTI features a better molecular ordering and two-dimensional charge delocalization, which help overcome the Coulomb interaction in the doped state. Consequently, free charges are more easily generated from charge-counterion pairs. This work provides a strategy for improving n-type thermoelectrics by tackling electrostatic interactions

Gradient microfluidics enables rapid bacterial growth inhibition testing

Bacterial growth inhibition tests have become a standard measure of the adverse effects of inhibitors for a wide range of applications, such as toxicity testing in the medical and environmental sciences. However, conventional well-plate formats for these tests are laborious and provide limited information (often being restricted to an end-point assay). In this study, we have developed a microfluidic system that enables fast quantification of the effect of an inhibitor on bacteria growth and survival, within a single experiment. This format offers a unique combination of advantages, including long-term continuous flow culture, generation of concentration gradients, and single cell morphology tracking. Using Escherichia coli and the inhibitor amoxicillin as one model system, we show excellent agreement between an on-chip single cell-based assay and conventional methods to obtain quantitative measures of antibiotic inhibition (for example, minimum inhibition concentration). Furthermore, we show that our methods can provide additional information, over and above that of the standard well-plate assay, including kinetic information on growth inhibition and measurements of bacterial morphological dynamics over a wide range of inhibitor concentrations. Finally, using a second model system, we show that this chip-based systems does not require the bacteria to be labeled and is well suited for the study of naturally occurring species. We illustrate this using Nitrosomonas europaea, an environmentally important bacteria, and show that the chip system can lead to a significant reduction in the period required for growth and inhibition measurements (<4 days, compared to weeks in a culture flask)

The current system associated with the boundary of plasma bubbles

The current system associated with the boundary of plasma bubbles in the Earth's magnetotail has been studied by employing Cluster multipoint observations. We have investigated the currents in both the dipolarization front (DF, leading edge of the plasma bubble) and the trailing edge of the plasma bubble. The distribution of currents at the edge indicates that there is a current circuit in the boundary of a plasma bubble. The field‐aligned currents in the trailing edge of the plasma bubble are flowing toward the ionosphere (downward) on the dawnside and away from the ionosphere (upward) on the duskside, in the same sense as region‐1 current. Together with previous studies of the current distributions in the DF and magnetic dip region, we have obtained a more complete picture of the current system surrounding the boundary of plasma bubble. This current system is very similar to the substorm current wedge predicted by MHD simulation models but with much smaller scale.Key PointsWe have obtained a current circuit in the boundary of plasma bubbleThe FACs in the trailing edge of plasma bubble is also region‐1‐senseThe current and FACs system is similar to SCW but with much smaller scalePeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/110641/1/grl52338.pd