Synthesis of photoacid crosslinkable hydrogels for the fabrication of soft, biomimetic microlens arrays

Soft, biomimetic microlens arrays were fabricated by interference lithography from the copolymers of poly(2-hydroxyethyl methacrylate), whose hydroxyl groups were crosslinked by photoacids and external crosslinkers

Countermeasure for Interrupted-sampling Repeater Jamming based on Fractional Fourier Transformation

Today, the interrupted-sampling repeater jamming (ISRJ) has posed a serious threat to LFM radars. In this paper, a countermeasure to suppressing ISRJ based on fractional Fourier transformation (FrFT) is presented. The echo signals, mixed with ISRJ, will be processed in FrFT of specific order, and then a narrow band filter based on parameters of FrFT is designed to extract the target signals and suppress interference signal, so as to realize the target detection. The three kinds of models of ISRJ (ISDRJ, ISRRJ, ISCRJ) are introduced; the anti-jamming principles are analyzed and simulated. The simulation results show that, the algorithm has low complexity and takes short operation time, and it is effective in low SNR or high JSR condition

Countermeasure for Interrupted-sampling Repeater Jamming based on Fractional Fourier Transformation

Today, the interrupted-sampling repeater jamming (ISRJ) has posed a serious threat to LFM radars. In this paper, a countermeasure to suppressing ISRJ based on fractional Fourier transformation (FrFT) is presented. The echo signals, mixed with ISRJ, will be processed in FrFT of specific order, and then a narrow band filter based on parameters of FrFT is designed to extract the target signals and suppress interference signal, so as to realize the target detection. The three kinds of models of ISRJ (ISDRJ, ISRRJ, ISCRJ) are introduced; the anti-jamming principles are analyzed and simulated. The simulation results show that, the algorithm has low complexity and takes short operation time, and it is effective in low SNR or high JSR condition

Microstructure Analysis and Fatigue Behavior of Laser Beam Welding 2060-T8/2099-T83 Aluminum–Lithium Alloys

In this paper, the microstructure analysis and performance research of dual laser beam welded 2060-T8/2099-T83 aluminum–lithium alloys were carried out. First, the macroscopic morphology and microstructure characteristics of T-joint aluminum–lithium alloys under different welding conditions were observed. Then the effect of welding parameters and pore defects on tensile and fatigue properties of the weld were carried out and the experimental results were analyzed. It was found that the weld heat input has a significant influence on the penetration of the welded aluminum–lithium alloys joint. When the laser power is too high, the weld will absorb more laser energy and the increase in the evaporation of magnesium will further increase the weld penetration. When the penetration depth increases, the transverse tensile strength tends to decrease. There is no obvious rule for the effect of pore defects on the tensile strength of the weld. At the same time, the heat input of the weld is inversely proportional to the porosity. When the weld heat input increases from 19.41 to 23.33 kJ/m, the porosity decreases from 5.35% to 2.08%. During the fatigue test, it was confirmed that the existence of pore defects would reduce the fatigue life of the weld. In addition, from the analysis of the fatigue fracture morphology it can be found that when the porosity is low, the weld toe is the main source of fatigue cracks. The crack propagation zone shows a typical beach pattern and the final fracture of the base metal presents the characteristics of a brittle fracture. While, when the porosity is high, the crack source is mainly located at the pore defects. T-joint fractures from the inside of the weld and the fracture in the final fracture zone have obvious pore defects and dimples

Nanoemulsified adlay bran oil reduces tyrosinase activity and melanin synthesis in B16F10 cells and zebrafish

The efficacy of oily components is often difficult to evaluate due to their incompatibility with most models. Here, we emulsified adlay bran oil (ABO), processed it to a nanoscale, and investigated its anti‐hyperpigmentation efficacy, assessed for its inhibitory effects against tyrosinase activity and melanin production, in an in vitro system (mouse melanoma B16F10 cells) and an in vivo system (zebrafish embryos). ABO induced dose‐dependent reductions in tyrosinase activity and melanin production in both the melanoma cells and zebrafish, without affecting viability. The efficacy of ABO was strongly influenced by emulsion particle size in the zebrafish but not in the cells. These results indicate that ABO has potential as a tyrosinase inhibitor and anti‐hyperpigmentation agent and that the emulsion system is an effective method for delivering the bioactive components of ABO to living systems that could be utilized for other oily components

Nanoemulsified adlay bran oil reduces tyrosinase activity and melanin synthesis in B16F10 cells and zebrafish

The efficacy of oily components is often difficult to evaluate due to their incompatibility with most models. Here, we emulsified adlay bran oil (ABO), processed it to a nanoscale, and investigated its anti‐hyperpigmentation efficacy, assessed for its inhibitory effects against tyrosinase activity and melanin production, in an in vitro system (mouse melanoma B16F10 cells) and an in vivo system (zebrafish embryos). ABO induced dose‐dependent reductions in tyrosinase activity and melanin production in both the melanoma cells and zebrafish, without affecting viability. The efficacy of ABO was strongly influenced by emulsion particle size in the zebrafish but not in the cells. These results indicate that ABO has potential as a tyrosinase inhibitor and anti‐hyperpigmentation agent and that the emulsion system is an effective method for delivering the bioactive components of ABO to living systems that could be utilized for other oily components

Non-invasive evaluation of endometrial microvessels via in vivo intrauterine photoacoustic endoscopy

The endometrium microvessel system, responsible for supplying oxygen and nutrients to the embryo, holds significant importance in evaluating endometrial receptivity (ER). Visualizing this system directly can significantly enhance ER evaluation. Currently, clinical methods like Narrow-band hysteroscopy and Color Doppler ultrasound are commonly used for uterine blood vessel examination, but they have limitations in depth or resolution. Endoscopic Photoacoustic Imaging (PAE) has proven effective in visualizing microvessels in the digestive tract, while its adaptation to uterine imaging faces challenges due to the uterus's unique physiological characteristics. This paper for the first time that uses high-resolution PAE in vivo to capture a comprehensive network of endometrial microvessels non-invasively. Followed by continuous observation and quantitative analysis in the endometrial injury model, we further corroborated that PAE detection of endometrial microvessels stands as a valuable indicator for evaluating ER. The PAE system showcases its promising potential for integration into reproductive health assessments

Additional file 1 of Bone-derived PDGF-BB enhances hippocampal non-specific transcytosis through microglia-endothelial crosstalk in HFD-induced metabolic syndrome

Supplementary Material