Gyrokinetic Landau collision operator in conservative form

A gyrokinetic linearized exact (not model) Landau collision operator is derived by transforming the symmetric and conservative Landau form. The formulation obtains the velocity-space flux density and preserves the operator's conservative form as the divergence of this flux density. The operator contains both test-particle and field-particle contributions, and finite Larmor radius effects are evaluated in either Bessel function series or gyrophase integrals. While equivalent to the gyrokinetic Fokker–Planck form with Rosenbluth potentials [B. Li and D. R. Ernst, Phys. Rev. Lett. 106, 195002 (2011)10.1103/PhysRevLett.106.195002], the gyrokinetic conservative Landau form explicitly preserves the symmetry between test-particle and field-particle contributions, which underlies the conservation laws and the H theorem, and enables discretization with a finite-volume or spectral method to preserve the conservation properties numerically, independent of resolution. The form of the exact linearized field-particle terms differs from those of widely used model operators. We show the finite Larmor radius corrections to the field-particle terms in the exact linearized operator involve Bessel functions of all orders, while present model field-particle terms involve only the first two Bessel functions. This new symmetric and conservative formulation enables the gyrokinetic exact linearized Landau operator to be implemented in gyrokinetic turbulence codes for comparison with present model operators using similar numerical methods.United States. Department of Energy (Contract DE-FC02-08ER54966

Interleukin-35 Expression in Non-Small Cell Lung Cancer is Associated with Tumor Progression

Background/Aims: Lung cancer continues to be the leading cause of cancer related deaths worldwide due to its high incidence, malignant behavior and lack of major advancements in treatment strategy. The occurrence and development of lung cancer is closely related to inflammation. Thus, we conducted the present study to investigate the effects of IL-35 (Interleukin 35), a newly identified anti-inflammatory factor, on non-small cell lung cancer (NSCLC), which accounts for about 85% of all lung cancers. Methods: We first evaluated the IL-35 expression in 384 pairs of NSCLC samples and their adjacent normal mucosa by realtime PCR, ELISA (Enzyme-linked immunoassay) and tissue microarrays. Then the role of IL-35 on patient survival rates, cancer progression and their sensitivity to chemotherapy drugs were assessed. Results: IL-35 was barely expressed in the NSCLC tissues but highly expressed in the adjacent normal tissues. The down-regulation of IL-35 was significantly correlated with the results of American Joint Committee on Cancer stage, differentiation and it was also shown to be an independent prognostic indicator of disease-free survival and overall survival for patients with NSCLC. Overexpression of IL-35 in NSCLC cells suppressed cell migration, invasion, proliferation, colony formation through suppressing β-catenin. IL-35 inhibited NSCLC formation in the mice model and sensitize the cancer cells to chemotherapy drugs. Conclusion: Our results showed that IL-35 plays an inhibitory role in NSCLC development and function as a novel prognostic indicator and a potential therapeutic target

Potential of Core-Collapse Supernova Neutrino Detection at JUNO

JUNO is an underground neutrino observatory under construction in Jiangmen, China. It uses 20kton liquid scintillator as target, which enables it to detect supernova burst neutrinos of a large statistics for the next galactic core-collapse supernova (CCSN) and also pre-supernova neutrinos from the nearby CCSN progenitors. All flavors of supernova burst neutrinos can be detected by JUNO via several interaction channels, including inverse beta decay, elastic scattering on electron and proton, interactions on C12 nuclei, etc. This retains the possibility for JUNO to reconstruct the energy spectra of supernova burst neutrinos of all flavors. The real time monitoring systems based on FPGA and DAQ are under development in JUNO, which allow prompt alert and trigger-less data acquisition of CCSN events. The alert performances of both monitoring systems have been thoroughly studied using simulations. Moreover, once a CCSN is tagged, the system can give fast characterizations, such as directionality and light curve

Detection of the Diffuse Supernova Neutrino Background with JUNO

As an underground multi-purpose neutrino detector with 20 kton liquid scintillator, Jiangmen Underground Neutrino Observatory (JUNO) is competitive with and complementary to the water-Cherenkov detectors on the search for the diffuse supernova neutrino background (DSNB). Typical supernova models predict 2-4 events per year within the optimal observation window in the JUNO detector. The dominant background is from the neutral-current (NC) interaction of atmospheric neutrinos with 12C nuclei, which surpasses the DSNB by more than one order of magnitude. We evaluated the systematic uncertainty of NC background from the spread of a variety of data-driven models and further developed a method to determine NC background within 15\% with {\it{in}} {\it{situ}} measurements after ten years of running. Besides, the NC-like backgrounds can be effectively suppressed by the intrinsic pulse-shape discrimination (PSD) capabilities of liquid scintillators. In this talk, I will present in detail the improvements on NC background uncertainty evaluation, PSD discriminator development, and finally, the potential of DSNB sensitivity in JUNO

Charged Particle Energization and Transport in the Magnetotail during Substorms

This dissertation addresses the problem of energization of particles (both electrons and ions) to tens and hundreds of keV and the associated transport process in the magnetotail during substorms. Particles energized in the magnetotail are further accelerated to even higher energies (hundreds of keV to MeV) in the radiation belts, causing space weather hazards to human activities in space and on ground. We develop an analytical model to quantitatively estimate flux changes caused by betatron and Fermi acceleration when particles are transported along narrow high-speed flow channels from the magnetotail to the inner magnetosphere. The model shows that energetic particle flux can be significantly enhanced by a modest compression of the magnetic field and/or shrinking of the distance between the magnetic mirror points. We use coordinated spacecraft measurements, global magnetohydrodynamic (MHD) simulations driven by measured upstream solar wind conditions, and large-scale kinetic (LSK) simulations to quantify electron local acceleration in the near-Earth reconnection region and nonlocal acceleration during plasma earthward transport. Compared to the analytical model, application of the LSK simulations is much less restrictive because trajectories of millions of test particles are calculated in the realistically determined global MHD fields and the results are statistical. The simulation results validated by the observations show that electrons following a power law distribution at high energies are generated earthward of the reconnection site, and that the majority of the energetic electrons observed in the inner magnetosphere are caused by adiabatic acceleration in association with magnetic dipolarizations and fast flows during earthward transport. We extend the global MHD+LSK simulations to examine ion energization and compare it with electron energization. The simulations demonstrate that ions in the magnetotail are first nonadiabatically accelerated in the weak field region close to the reconnection site, and then adiabatically accelerated in the high-speed flow channels as they catch up with and ride on the earthward propagating dipolarization structures. The nonlocal adiabatic acceleration mechanism for ions is very similar to that for electrons. However, the motion of energetic electrons is adiabatic except in very limited regions near the reconnection site while the motion of energetic ions is marginally adiabatic in the dipolarization regions. The simulations also show that the earthward transport of both species is controlled by the high-speed flows via the dominant ExB drift in the magnetotail. To understand how the power law electrons are initially produced in the magnetotail, we use an implicit particle-in-cell (PIC) code to model the processes in the near-Earth reconnection region. We find that the power law electrons are produced not in the reconnection diffusion region, but in the immediate downstream of the reconnection outflow in the course of dipolarization formation and intensification. Our study illustrates that during substorms, particles are accelerated via a multi-step process, including local acceleration in the reconnection region and nonlocal acceleration during the earthward transport, and the multi-step acceleration occurs on multiple spatial scales ranging from a few kilometers (the scale of electron diffusion region) to more than ten Earth radii (the transport scale)

Gyrokinetic Landau collision operator in conservative form

A gyrokinetic linearized exact (not model) Landau collision operator is derived by transforming the symmetric and conservative Landau form. The formulation obtains the velocity-space flux density and preserves the operator’s conservative form as the divergence of this flux density. The operator contains both test-particle and field-particle contributions, and finite Larmor radius effects are evaluated in either Bessel function series or gyrophase integrals. While equivalent to the gyrokinetic Fokker–Planck form with Rosenbluth potentials [B. Li and D. R. Ernst, Phys. Rev. Lett. 106, 195002 (2011)], the gyrokinetic conservative Landau form explicitly preserves the symmetry between test-particle and field-particle contributions, which underlies the conservation laws and the H theorem, and enables discretization with a finite-volume or spectral method to preserve the conservation properties numerically, independent of resolution. The form of the exact linearized field-particle terms differs from those of widely used model operators. We show the finite Larmor radius corrections to the field-particle terms in the exact linearized operator involve Bessel functions of all orders, while present model field-particle terms involve only the first two Bessel functions. This new symmetric and conservative formulation enables the gyrokinetic exact linearized Landau operator to be implemented in gyrokinetic turbulence codes for comparison with present model operators using similar numerical methods

CO Electroreduction Mechanism on Single-Atom Zn (101) Surfaces: Pathway to C2 Products

Electrocatalytic reduction of carbon dioxide (CO2RR) employs electricity to store renewable energy in the form of reduction products. The activity and selectivity of the reaction depend on the inherent properties of electrode materials. Single-atom alloys (SAAs) exhibit high atomic utilization efficiency and unique catalytic activity, making them promising alternatives to precious metal catalysts. In this study, density functional theory (DFT) was employed to predict stability and high catalytic activity of Cu/Zn (101) and Pd/Zn (101) catalysts in the electrochemical environment at the single-atom reaction site. The mechanism of C2 products (glyoxal, acetaldehyde, ethylene, and ethane) produced by electrochemical reduction on the surface was elucidated. The C-C coupling process occurs through the CO dimerization mechanism, and the formation of the *CHOCO intermediate proves beneficial, as it inhibits both HER and CO protonation. Furthermore, the synergistic effect between single atoms and Zn results in a distinct adsorption behavior of intermediates compared to traditional metals, giving SAAs unique selectivity towards the C2 mechanism. At lower voltages, the Zn (101) single-atom alloy demonstrates the most advantageous performance in generating ethane on the surface, while acetaldehyde and ethylene exhibit significant certain potential. These findings establish a theoretical foundation for the design of more efficient and selective carbon dioxide catalysts

Fabrication of ZnO@Plant Polyphenols/Cellulose as Active Food Packaging and Its Enhanced Antibacterial Activity

To investigate the efficient use of bioresources and bioproducts, plant polyphenol (PPL) was extracted from larch bark and further applied to prepare ZnO@PPL/Cel with cellulose to examine its potential as an active package material. The structure and morphology were fully characterized by XRD, SEM, FTIR, XPS and Raman spectra. It was found that PPL is able to cover ZnO and form a coating layer. In addition, PPL cross-links with cellulose and makes ZnO distribute evenly on the cellulose fibers. Coating with PPL creates a pinecone-like morphology in ZnO, which is constructed by subunits of 50 nm ZnO slices. The interactions among ZnO, PPL and cellulose have been attributed to hydrogen bonding, which plays an important role in guiding the formation of composites. The antibacterial properties against Gram-negative Escherichia coli (E. coli) and Gram-positive Staphylococcus aureus (S. aureus) were tested by the inhibition zone method. Our composite ZnO@PPL/Cel has superior antibacterial activity compared to ZnO/Cel. The antibacterial mechanism has also been elaborated on. The low cost, simple preparation method and good performance of ZnO@PPL/Cel suggest the potential for it to be applied as active food packaging

Surface structure deduced differences of copper foil and film for graphene CVD growth

Graphene was synthesized on Cu foil and film by atmospheric pressure chemical vapor deposition (CVD) with CH4 as carbon source. Electron backscattered scattering diffraction (EBSD) characterization demon strates that the Cu foil surface after the H-2-assisted pre-annealing was almost composed of Cu(100) crystal facet with larger grain size of similar to 100 mu m; meanwhile, the Cu film surface involved a variety of crystal facets of Cu(111), Cu(100), and Cu(110), with the relatively small grain size of similar to 10 mu m. The different surface structure led to the distinctive influences of the CH4 and H-2 concentrations on the thickness and quality of as-grown graphene. Further data demonstrate that the Cu foil enabled more nucleation densities and faster growth rates at the initial growth stages than the Cu film. Our results are beneficial for understanding the relationship between the metal surface structure and graphene CVD growth. (C) 2014 Elsevier B.V. All rights reserved