63 research outputs found
Deep Landscape Forecasting for Real-time Bidding Advertising
The emergence of real-time auction in online advertising has drawn huge
attention of modeling the market competition, i.e., bid landscape forecasting.
The problem is formulated as to forecast the probability distribution of market
price for each ad auction. With the consideration of the censorship issue which
is caused by the second-price auction mechanism, many researchers have devoted
their efforts on bid landscape forecasting by incorporating survival analysis
from medical research field. However, most existing solutions mainly focus on
either counting-based statistics of the segmented sample clusters, or learning
a parameterized model based on some heuristic assumptions of distribution
forms. Moreover, they neither consider the sequential patterns of the feature
over the price space. In order to capture more sophisticated yet flexible
patterns at fine-grained level of the data, we propose a Deep Landscape
Forecasting (DLF) model which combines deep learning for probability
distribution forecasting and survival analysis for censorship handling.
Specifically, we utilize a recurrent neural network to flexibly model the
conditional winning probability w.r.t. each bid price. Then we conduct the bid
landscape forecasting through probability chain rule with strict mathematical
derivations. And, in an end-to-end manner, we optimize the model by minimizing
two negative likelihood losses with comprehensive motivations. Without any
specific assumption for the distribution form of bid landscape, our model shows
great advantages over previous works on fitting various sophisticated market
price distributions. In the experiments over two large-scale real-world
datasets, our model significantly outperforms the state-of-the-art solutions
under various metrics.Comment: KDD 2019. The reproducible code and dataset link is
https://github.com/rk2900/DL
Reversible Deep Neural Network Watermarking:Matching the Floating-point Weights
Static deep neural network (DNN) watermarking embeds watermarks into the
weights of DNN model by irreversible methods, but this will cause permanent
damage to watermarked model and can not meet the requirements of integrity
authentication. For these reasons, reversible data hiding (RDH) seems more
attractive for the copyright protection of DNNs. This paper proposes a novel
RDH-based static DNN watermarking method by improving the non-reversible
quantization index modulation (QIM). Targeting the floating-point weights of
DNNs, the idea of our RDH method is to add a scaled quantization error back to
the cover object. Two schemes are designed to realize the integrity protection
and legitimate authentication of DNNs. Simulation results on training loss and
classification accuracy justify the superior feasibility, effectiveness and
adaptability of the proposed method over histogram shifting (HS).Comment: 21 page
Lifelong Sequential Modeling with Personalized Memorization for User Response Prediction
User response prediction, which models the user preference w.r.t. the
presented items, plays a key role in online services. With two-decade rapid
development, nowadays the cumulated user behavior sequences on mature Internet
service platforms have become extremely long since the user's first
registration. Each user not only has intrinsic tastes, but also keeps changing
her personal interests during lifetime. Hence, it is challenging to handle such
lifelong sequential modeling for each individual user. Existing methodologies
for sequential modeling are only capable of dealing with relatively recent user
behaviors, which leaves huge space for modeling long-term especially lifelong
sequential patterns to facilitate user modeling. Moreover, one user's behavior
may be accounted for various previous behaviors within her whole online
activity history, i.e., long-term dependency with multi-scale sequential
patterns. In order to tackle these challenges, in this paper, we propose a
Hierarchical Periodic Memory Network for lifelong sequential modeling with
personalized memorization of sequential patterns for each user. The model also
adopts a hierarchical and periodical updating mechanism to capture multi-scale
sequential patterns of user interests while supporting the evolving user
behavior logs. The experimental results over three large-scale real-world
datasets have demonstrated the advantages of our proposed model with
significant improvement in user response prediction performance against the
state-of-the-arts.Comment: SIGIR 2019. Reproducible codes and datasets:
https://github.com/alimamarankgroup/HPM
CoRide: Joint Order Dispatching and Fleet Management for Multi-Scale Ride-Hailing Platforms
How to optimally dispatch orders to vehicles and how to tradeoff between
immediate and future returns are fundamental questions for a typical
ride-hailing platform. We model ride-hailing as a large-scale parallel ranking
problem and study the joint decision-making task of order dispatching and fleet
management in online ride-hailing platforms. This task brings unique challenges
in the following four aspects. First, to facilitate a huge number of vehicles
to act and learn efficiently and robustly, we treat each region cell as an
agent and build a multi-agent reinforcement learning framework. Second, to
coordinate the agents from different regions to achieve long-term benefits, we
leverage the geographical hierarchy of the region grids to perform hierarchical
reinforcement learning. Third, to deal with the heterogeneous and variant
action space for joint order dispatching and fleet management, we design the
action as the ranking weight vector to rank and select the specific order or
the fleet management destination in a unified formulation. Fourth, to achieve
the multi-scale ride-hailing platform, we conduct the decision-making process
in a hierarchical way where a multi-head attention mechanism is utilized to
incorporate the impacts of neighbor agents and capture the key agent in each
scale. The whole novel framework is named as CoRide. Extensive experiments
based on multiple cities real-world data as well as analytic synthetic data
demonstrate that CoRide provides superior performance in terms of platform
revenue and user experience in the task of city-wide hybrid order dispatching
and fleet management over strong baselines.Comment: CIKM 201
Tetraploidy in Citrus wilsonii Enhances Drought Tolerance via Synergistic Regulation of Photosynthesis, Phosphorylation, and Hormonal Changes
Polyploidy varieties have been reported to exhibit higher stress tolerance relative to their diploid relatives, however, the underlying molecular and physiological mechanisms remain poorly understood. In this study, a batch of autotetraploid Citrus wilsonii were identified from a natural seedling population, and these tetraploid seedlings exhibited greater tolerance to drought stress than their diploids siblings. A global transcriptome analysis revealed that a large number of genes involved in photosynthesis response were enriched in tetraploids under drought stress, which was consistent with the changes in photosynthetic indices including Pn, gs, Tr, Ci, and chlorophyll contents. Compared with diploids, phosphorylation was also modified in the tetraploids after drought stress, as detected through tandem mass tag (TMT)-labeled proteomics. Additionally, tetraploids prioritized the regulation of plant hormone signal transduction at the transcriptional level after drought stress, which was also demonstrated by increased levels of IAA, ABA, and SA and reduced levels of GA3 and JA. Collectively, our results confirmed that the synergistic regulation of photosynthesis response, phosphorylation modification and plant hormone signaling resulted in drought tolerance of autotetraploid C. wilsonii germplasm
Local Diffusion Homogeneity Provides Supplementary Information in T2DM-Related WM Microstructural Abnormality Detection
Objectives: We aimed to investigate whether an inter-voxel diffusivity metric (local diffusion homogeneity, LDH), can provide supplementary information to traditional intra-voxel metrics (i.e., fractional anisotropy, FA) in white matter (WM) abnormality detection for type 2 diabetes mellitus (T2DM).Methods: Diffusion tensor imaging was acquired from 34 T2DM patients and 32 healthy controls. Voxel-based group-difference comparisons based on LDH and FA, as well as the association between the diffusion metrics and T2DM risk factors [i.e., body mass index (BMI) and systolic blood pressure (SBP)], were conducted, with age, gender and education level controlled.Results: Compared to the controls, T2DM patients had higher LDH in the pons and left temporal pole, as well as lower FA in the left superior corona radiation (p < 0.05, corrected). In T2DM, there were several overlapping WM areas associated with BMI as revealed by both LDH and FA, including right temporal lobe and left inferior parietal lobe; but the unique areas revealed only by using LDH included left inferior temporal lobe, right supramarginal gyrus, left pre- and post-central gyrus (at the semiovale center), and right superior radiation. Overlapping WM areas that associated with SBP were found with both LDH and FA, including right temporal pole, bilateral orbitofrontal area (rectus gyrus), the media cingulum bundle, and the right cerebellum crus I. However, the unique areas revealed only by LDH included right inferior temporal lobe, right inferior occipital lobe, and splenium of corpus callosum.Conclusion: Inter- and intra-voxel diffusivity metrics may have different sensitivity in the detection of T2DM-related WM abnormality. We suggested that LDH could provide supplementary information and reveal additional underlying brain changes due to diabetes
Comparative analysis of sequencing technologies for single-cell transcriptomics.
Single-cell RNA-seq technologies require library preparation prior to sequencing. Here, we present the first report to compare the cheaper BGISEQ-500 platform to the Illumina HiSeq platform for scRNA-seq. We generate a resource of 468 single cells and 1297 matched single cDNA samples, performing SMARTer and Smart-seq2 protocols on two cell lines with RNA spike-ins. We sequence these libraries on both platforms using single- and paired-end reads. The platforms have comparable sensitivity and accuracy in terms of quantification of gene expression, and low technical variability. Our study provides a standardized scRNA-seq resource to benchmark new scRNA-seq library preparation protocols and sequencing platforms
Knockdown BMI1 expression inhibits proliferation and invasion in human bladder cancer T24 cells
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