4 research outputs found
Catalyst-Enabled Scaffold Diversity: Highly Chemo- and Stereoselective Synthesis of Tricyclic Ketals and Triarylmethanes
The first catalytic
cascade reaction of activated isocyanides with <i>para</i>-quinone methide-aryl esters is presented. Catalyst-enabled
divergent pathways have also been achieved to deliver skeletally diverse
products. While Ag catalysis leads to an unprecedented highly diastereoselective
synthesis of tricyclic ketals, a simple procedure employing Cu catalysis
produces oxazole-containing triarylmethanes in high efficiency through
an unexpected C–C bond cleavage
Catalyst-Enabled Scaffold Diversity: Highly Chemo- and Stereoselective Synthesis of Tricyclic Ketals and Triarylmethanes
The first catalytic
cascade reaction of activated isocyanides with <i>para</i>-quinone methide-aryl esters is presented. Catalyst-enabled
divergent pathways have also been achieved to deliver skeletally diverse
products. While Ag catalysis leads to an unprecedented highly diastereoselective
synthesis of tricyclic ketals, a simple procedure employing Cu catalysis
produces oxazole-containing triarylmethanes in high efficiency through
an unexpected C–C bond cleavage
Catalyst-Enabled Scaffold Diversity: Highly Chemo- and Stereoselective Synthesis of Tricyclic Ketals and Triarylmethanes
The first catalytic
cascade reaction of activated isocyanides with <i>para</i>-quinone methide-aryl esters is presented. Catalyst-enabled
divergent pathways have also been achieved to deliver skeletally diverse
products. While Ag catalysis leads to an unprecedented highly diastereoselective
synthesis of tricyclic ketals, a simple procedure employing Cu catalysis
produces oxazole-containing triarylmethanes in high efficiency through
an unexpected C–C bond cleavage
Catalyst-Enabled Scaffold Diversity: Highly Chemo- and Stereoselective Synthesis of Tricyclic Ketals and Triarylmethanes
The first catalytic
cascade reaction of activated isocyanides with <i>para</i>-quinone methide-aryl esters is presented. Catalyst-enabled
divergent pathways have also been achieved to deliver skeletally diverse
products. While Ag catalysis leads to an unprecedented highly diastereoselective
synthesis of tricyclic ketals, a simple procedure employing Cu catalysis
produces oxazole-containing triarylmethanes in high efficiency through
an unexpected C–C bond cleavage