159 research outputs found

    Exploring Musical, Lyrical, and Network Dimensions of Music Sharing Among Depression Individuals

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    Depression has emerged as a significant mental health concern due to a variety of factors, reflecting broader societal and individual challenges. Within the digital era, social media has become an important platform for individuals navigating through depression, enabling them to express their emotional and mental states through various mediums, notably music. Specifically, their music preferences, manifested through sharing practices, inadvertently offer a glimpse into their psychological and emotional landscapes. This work seeks to study the differences in music preferences between individuals diagnosed with depression and non-diagnosed individuals, exploring numerous facets of music, including musical features, lyrics, and musical networks. The music preferences of individuals with depression through music sharing on social media, reveal notable differences in musical features and topics and language use of lyrics compared to non-depressed individuals. We find the network information enhances understanding of the link between music listening patterns. The result highlights a potential echo-chamber effect, where depression individual's musical choices may inadvertently perpetuate depressive moods and emotions. In sum, this study underscores the significance of examining music's various aspects to grasp its relationship with mental health, offering insights for personalized music interventions and recommendation algorithms that could benefit individuals with depression.Comment: arXiv admin note: text overlap with arXiv:2007.03137, arXiv:2205.03459 by other author

    Mechanics of Supercooled Liquids

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    Pure substances can often be cooled below their melting points and still remain in the liquid state. For some supercooled liquids, a further cooling slows down viscous flow greatly, but does not slow down self-diffusion as much. We formulate a continuum theory that regards viscous flow and self-diffusion as concurrent, but distinct, processes. We generalize Newton’s law of viscosity to relate stress, rate of deformation, and chemical potential. The self-diffusion flux is taken to be proportional to the gradient of chemical potential. The relative rate of viscous flow and self-diffusion defines a length, which, for some supercooled liquids, is much larger than the molecular dimension. A thermodynamic consideration leads to boundary conditions for a surface of liquid under the influence of applied traction and surface energy. We apply the theory to a cavity in a supercooled liquid and identify a transition. A large cavity shrinks by viscous flow, and a small cavity shrinks by self-diffusion.Engineering and Applied Science

    Data-driven approach for modeling Reynolds stress tensor with invariance preservation

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    The present study represents a data-driven turbulent model with Galilean invariance preservation based on machine learning algorithm. The fully connected neural network (FCNN) and tensor basis neural network (TBNN) [Ling et al. (2016)] are established. The models are trained based on five kinds of flow cases with Reynolds Averaged Navier-Stokes (RANS) and high-fidelity data. The mappings between two invariant sets, mean strain rate tensor and mean rotation rate tensor as well as additional consideration of invariants of turbulent kinetic energy gradients, and the Reynolds stress anisotropy tensor are trained. The prediction of the Reynolds stress anisotropy tensor is treated as user's defined RANS turbulent model with a modified turbulent kinetic energy transport equation. The results show that both FCNN and TBNN models can provide more accurate predictions of the anisotropy tensor and turbulent state in square duct flow and periodic flow cases compared to the RANS model. The machine learning based turbulent model with turbulent kinetic energy gradient related invariants can improve the prediction precision compared with only mean strain rate tensor and mean rotation rate tensor based models. The TBNN model is able to predict a better flow velocity profile compared with FCNN model due to a prior physical knowledge.Comment: 23 page

    Egress of HSV-1 capsid requires the interaction of VP26 and a cellular tetraspanin membrane protein

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    HSV-1 viral capsid maturation and egress from the nucleus constitutes a self-controlled process of interactions between host cytoplasmic membrane proteins and viral capsid proteins. In this study, a member of the tetraspanin superfamily, CTMP-7, was shown to physically interact with HSV-1 protein VP26, and the VP26-CTMP-7 complex was detected both in vivo and in vitro. The interaction of VP26 with CTMP-7 plays an essential role in normal HSV-1 replication. Additionally, analysis of a recombinant virus HSV-1-UG showed that mutating VP26 resulted in a decreased viral replication rate and in aggregation of viral mutant capsids in the nucleus. Together, our data support the notion that biological events mediated by a VP26 - CTMP-7 interaction aid in viral capsid enveloping and egress from the cell during the HSV-1 infectious process

    Elastomeric substrates with embedded stiff platforms for stretchable electronics

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    Stretchable electronics typically integrate hard, functional materials on soft substrates. Here we report on engineered elastomeric substrates designed to host stretchable circuitry. Regions of a stiff material, patterned using photolithography, are embedded within a soft elastomer leaving a smooth surface. We present the associated design rules to produce stretchable circuits based on experimental as well as modeling data. We demonstrate our approach with thin-film electronic materials. The "customized" elastomeric substrates may also be used as a generic elastic substrate for stretchable circuits prepared with alternative technologies, such as transfer-printing of inorganic, thinned devices. (C) 2013 American Institute of Physics. [http://dx.doi.org/10.1063/1.4799653
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