8 research outputs found

    Socialized Farmland Operation—An Institutional Interpretation of Farmland Scale Management

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    Farmland scale management is an important approach for developing countries to ensure food security in the face of the COVID-19 pandemic. At present, the realization of farmland scale management through the path of farmland use rights trading encounters obstacles in practice; moreover, the new model of farmland scale management has rarely been systematically discussed. Considering the farmland trusteeship practice implemented in Shandong Province of China as the research case, this study discusses the essence and realization premise of the new farmland scale management model represented by farmland trusteeship based on case analysis. The conclusions are as follows. (1) The high cost generated from farmland scale management is the main obstacle to realize this model. (2) The process of realizing farmland scale management through farmland trusteeship is actually the process of meeting the requirements of the socialization of farmland use, the socialization of the farmland management process, and the socialization of farmland output. Thus, in the context of the existence of a large number of small and scattered farmers in China, the socialized farmland operation is the essence of farmland scale management. (3) Effective collective action is the premise of realizing socialized farmland operation. Undeniably, a lot more systematic explorations are further demanded to strengthen the irrigation management and infrastructures, promote and ensure stable village leadership, and comprehensively improve the ability of rural collective action to ensure the further strengthening of socialized farmland operation so as to realize stable farmland scale management, which will be pursued in the future

    Deregulation of Serum MicroRNA Expression Is Associated with Cigarette Smoking and Lung Cancer

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    Lung cancer is the leading cause of cancer-related death and cigarette smoking is the main risk factor for lung cancer. Circulating microRNAs (miRNAs) are considered potential biomarkers of various cancers, including lung cancer. However, it is unclear whether changes in circulating miRNAs are associated with smoking and smoking-related lung cancer. In this study, we determined the serum miRNA profiles of 10 nonsmokers, 10 smokers, and 10 lung-cancer patients with miRCURY LNA microRNA arrays. The differentially expressed miRNAs were then confirmed in a larger sample. We found that let-7i-3p and miR-154-5p were significantly downregulated in the sera of smokers and lung-cancer patients, so the serum levels of let-7i-3p and miR-154-5p are associated with smoking and smoking-related lung cancer. The areas under receiver operating characteristic curves for let-7i-3p and miR-154-5p were approximately 0.892 and 0.957, respectively. In conclusion, our results indicate that changes in serum miRNAs are associated with cigarette smoking and lung cancer and that let-7i-3p and miR-154-5p are potential biomarkers of smoking-related lung cancer

    Deregulation of Serum MicroRNA Expression Is Associated with Cigarette Smoking and Lung Cancer

    No full text
    Lung cancer is the leading cause of cancer-related death and cigarette smoking is the main risk factor for lung cancer. Circulating microRNAs (miRNAs) are considered potential biomarkers of various cancers, including lung cancer. However, it is unclear whether changes in circulating miRNAs are associated with smoking and smoking-related lung cancer. In this study, we determined the serum miRNA profiles of 10 nonsmokers, 10 smokers, and 10 lung-cancer patients with miRCURY LNA microRNA arrays. The differentially expressed miRNAs were then confirmed in a larger sample. We found that let-7i-3p and miR-154-5p were significantly downregulated in the sera of smokers and lung-cancer patients, so the serum levels of let-7i-3p and miR-154-5p are associated with smoking and smoking-related lung cancer. The areas under receiver operating characteristic curves for let-7i-3p and miR-154-5p were approximately 0.892 and 0.957, respectively. In conclusion, our results indicate that changes in serum miRNAs are associated with cigarette smoking and lung cancer and that let-7i-3p and miR-154-5p are potential biomarkers of smoking-related lung cancer

    A Quasi-Randomized Controlled Trial of an Integrated Healthcare Model for Patients with Coronary Heart Disease

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    Background: An increasing number of coronary heart disease (CHD) patients with an aging population are demanding available and effective out-of-hospital continuous healthcare services. However, great efforts still need to be made to promote out-of-hospital healthcare services for better CHD secondary prevention. This study aims to evaluate the effectiveness of a hospital-community-family (HCF)-based integrated healthcare model on treatment outcomes, treatment compliance, and quality of life (QoL) in CHD patients. Methods: A quasi-randomized controlled trial was conducted at the Department of Cardiology, a tertiary A-level hospital, Wuhan, China from January 2018 to January 2020 in accordance with the Consolidated Standards of Reporting Trials guidelines. CHD patients were enrolled from the hospital and quasi-randomly assigned to either HCF-based integrated healthcare model services or conventional healthcare services. The treatment outcomes and QoL were observed at the 12-month follow-up. Treatment compliance was observed at the 1-month and 12-month follow-ups. Results: A total of 364 CHD patients were quasi-randomly assigned to either integrated healthcare model services (n = 190) or conventional healthcare services (n = 174). Treatment outcomes including relapse and readmission rate (22.6% vs 41.9%; relative risk [RR] = 0.54; 95% confidence interval [CI], 0.40–0.74; p = 0.0031), the occurrence of major cardiovascular events (19.5% vs 45.4%; RR = 0.43; 95% CI, 0.30–0.59; p = 0.0023), complication rate (19.5% vs 35.0%; RR = 0.56; 95% CI, 0.39–0.79; p = 0.0042), and the control rate of CHD risk factors (p 0.05, average p = 0.872). Treatment compliance at the 12-month follow-up in the intervention group, including correct medication, reasonable diet, adherence to exercise, emotional control, self-monitoring, and regular re-examination, was higher than that of the control group (p < 0.05, average p = 0.007). No difference was found in the compliance with smoking cessation and alcohol restriction at the 12-month follow-up between groups (p = 0.043). QoL at the 12-month follow-up in the intervention group was better than that of the control group (86.31 ± 9.39 vs 73.02 ± 10.70, p = 0.0048). Conclusions: The integrated healthcare model effectively improves treatment outcomes, long-term treatment compliance, and QoL of patients, and could be implemented as a feasible strategy for CHD secondary prevention

    Solvothermally Synthesized Co(CoO)/Ti<sub>3</sub>C<sub>2</sub>T<sub><i>x</i></sub>/TiO<sub>2</sub> Nanocomposites for Enhanced Microwave Absorption

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    Ti3C2Tx MXene has already been studied as an appealing microwave absorption material, benefiting from its fascinating laminated structure. Nevertheless, the single absorption mechanism of pure Ti3C2Tx MXene results in poor impedance matching. In this paper, magnetic Co nanoparticles were introduced on Ti3C2Tx MXene by using a simple solvothermal method. By introducing different contents of Co nanoparticles, the impedance matching and magnetic properties of the Co(CoO)/Ti3C2Tx/TiO2 nanocomposites could be optimized. It is demonstrated that the effective absorption bandwidth of Co(CoO)/Ti3C2Tx/TiO2 nanocomposites is 5.84 GHz (6.88–12.72 GHz), while the minimum reflection loss is −61.02 dB. Comparatively, our Co(CoO)/Ti3C2Tx/TiO2 nanocomposites exhibited better satisfied microwave absorption performance. The potential mechanism of microwave absorption was fully explored. Our report provides a simple and safe method to design high-efficiency absorbers which rely on Ti3C2Tx
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