Trichlorido-1κ2 Cl,2κCl-(2,6-dimethyl­phenolato-2κO)-μ-oxido-bis{1,2(η5)-2,3,4,5-tetra­methyl-1-[4-(trimethyl­silyl)phen­yl]cyclo­penta­dien­yl}dititanium(IV)

The title dinuclear titanocene, [Ti2(C8H9O)(C18H25Si)2Cl3O], contains one Ti atom tetra­hedrally coordinated by two Cl atoms, a bridging O atom and the substituted cyclo­penta­dienyl ligand, and another Ti atom tetra­hedrally coordinated by a Cl atom, a bridging O atom, the 2,6-dimethyl­phenolate ligand and the substituted cyclo­penta­dienyl ligand. The bridging O atom lies on a twofold rotation axis

{(1R,2R)-N,N′-Bis[2-(N-methyl­anilino)benzyl­idene]cyclo­hexane-1,2-diamine-κ2 N,N′}dichloridoiron(II)

In the title compound, [FeCl2(C34H36N4)], the FeII ion is coordinated by two Cl atoms and by two N atoms from a (1R,2R)-N,N′-bis[2-(N-methyl­anilino)benzyl­idene]cyclo­hexane-1,2-diamine ligand in a distorted tetra­hedral geometry. The mol­ecule has approximate C 2 point symmetry. The dihedral angles between the phenyl and benzene rings on either side of the ligand are 64.56 (14) and 65.61 (13)°

N,N′-Bis(2,6-diethyl­phen­yl)acenaphthyl­ene-1,2-diimine

The title compound, C32H32N2, has crystallographic twofold rotation symmetry, with two C atoms lying on the rotation axis. The dihedral angle between the substituted benzene ring and the naphthalene ring system is 79.8 (1)°. The crystal structure is stabilized by C—H⋯N inter­actions, which form a chain motif along the b-axis direction

Nomogram for Predicting Bone Development State of Female Children and Adolescents–A Fast Screening Approach Based on Pubes Stages for Growth and Development

Objective: To develop a nomogram for predicting bone development state (BDS) of female children and adolescents in a large scale.Methods: Four hundred forty-seven female students were designated as the training cohort to develop the predictive model, whereas 196 female students were used as the validation cohort to verify the established model. Bone age, height, body mass, body fat percentage, and secondary sexual characteristics were recorded, and BDS was determined with the chronological age and bone age. Multivariate logistic regression was conducted to determine the factors, and nomogram was developed and validated with the training and validation cohorts, respectively.Results: One hundred forty-seven female students were identified as BDS abnormal in the training cohort (32.9%), and 104 were determined in the validation cohort (53.1%). Age, height, weight, and pubes stage were selected for the predictive model. A nomogram was developed and showed a good estimation, with a C-index of 0.78 and a good calibration in the training cohort. Application of the nomogram to the validation cohort showed a similar C-index of 0.75 and a good calibration.Conclusion: A nomogram for predicting bone development was developed, which can provide a relatively good estimation of BDS for female children and adolescents in Chinese metropolis

FTN Signaling-Aided Space-Time Multi-Mode Index Modulation Systems With a GMP-Based Receiver

In this paper, we propose a faster-than-Nyquist (FTN) signaling-aided space-time multi-mode index modulation (IM) scheme with a low-complexity Gaussian message passing (GMP) based receiver. The advantages of spatial domain IM, time-domain IM relying on multiple modes and FTN signaling are explored. Specifically, multi-mode IM is employed in time domain by activating all time slots, hence the spectral efficiency is improved substantially compared to its single-mode counterpart. Meanwhile, the transmission rate is further increased by utilizing FTN signaling. At the receiver, based on the state-space model of IM symbols, a two-layer Forney style factor graph (FG) representation for the system is constructed to exploit the truncated inter-symbol interference structure imposed by FTN. Belief propagation is invoked to update the messages over the FG. The discrete messages from the channel decoder are properly approximated to be Gaussian for reducing the complexity of joint detection of multidimensional index modulated symbols. Moreover, the extrinsic information from the equalizer is derived with a concise representation. A low-complexity log-likelihood ratio calculation method is further proposed, where the search space is significantly reduced using a Gaussian mixture model. Simulation results demonstrate that the proposed scheme outperforms the existing schemes in terms of bit error rate given the same spectral efficiency. The outstanding performance and low complexity of the proposed GMP-based receiver are also verified by comparisons with existing methods

Measurement Uncertainty Analysis of the Stitching Linear-Scan Method for the Measurable Dimension of Small Cylinders

A stitching linear scan method is proposed for roundness and diameter measurement of small cylindrical workpieces instead of the conventional rotary scan method due to the crucial alignments of eccentricity and inclination. To verify the reliability of the proposed method, by which the coordinates of the cross-sectional circle of a small cylinder is divided into several equal parts to be obtained and reconstructed, the diameter and roundness measurement uncertainties of the small cylinders with a diameter 1.5 mm are evaluated to be 0.047 μm and 0.095 μm, respectively, which can meet the uncertainty target of 0.1 μm. To investigate the measurable dimension by the proposed method, measurement uncertainty analysis of the small cylinders with various dimensions has been conducted according to the previous evaluation, since all the procedures are the same except for the uncertainty of X coordinates, which changes with the measured dimension’s change. The results show that the small cylinders with a diameter range from 0.01 mm to 50 mm can be measured by the proposed method when the position error θZ is reduced to the corresponding value. There is no measuring limitation set by the proposed model theoretically in the case of θX = θZ = 0.1°, while the machine has a measuring limitation

Nomogram predicting overall prognosis for invasive micropapillary carcinoma of the breast: a SEER-based population study

Objectives The prognosis of invasive micropapillary carcinoma (IMPC) of the breast is determined by many clinicopathological factors. This study aims to identify prognostic factors and develop reliable nomogram to predict the overall survival (OS) in patients with IMPC.Design Log-rank test and Cox proportional hazards analysis were used to identify variables and construct a nomogram based on the training cohort. C-index and calibration curves were performed to evaluate the performance of the model in the training cohort and validation cohorts.Setting We collected the patient data from the Surveillance, Epidemiology and End Results (SEER) database. This database holds data related to the cancer incidence from 18 population-based cancer registries in the USA.Participants The SEER database was used to screen 754 eligible patients as the study cohort. The whole cohort was randomly divided into a training cohort (n=377) and a validation cohort (n=377).Results Age at diagnosis, hormone receptors, number of positive regional lymph nodes and clinical stage were independent prognostic factors for patients with IMPC. The calibration curves presented excellent consistency between the actual and nomogram-predict survival probabilities in the training and validation cohorts. The C-index values of the nomogram were 0.794 and 0.774 for OS in the training and validation cohorts, respectively.Conclusions The novel nomogram provides new insights of the risk of each prognostic factor and can assist doctors in predicting the 1-year, 3-year and 5-year OS in patients with IMPC