562 research outputs found

    Eccrine chromhidrosis: A case report and review of literature

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    Chromhidrosis is a rare disorder characterized by colored sweat and/or stained skin. Eccrine chromhidrosis is an orphan disease in which water-soluble pigments are excreted through the eccrine glands. This article provides a highly doubtful eccrine chromhidrosis case and the literature review for eccrine chromhidrosis. We recommend an investigative algorithm for dermatologists, hepatologist, and general practitioners to enhance diagnostic capability without mistake among similar and differential diseases. Most importantly, the exact etiology should be determined, which further decides the treatment plan. Systemic treatment of liver diseases or bacteremia was reported particularly effective. Results and prognosis were excellent and without recurrence

    General bound states in the continuum in momentum space

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    Polarization singularities including bound states in the continuum (BICs) and circularly polarized states have provided promising opportunities in the manipulation of light waves. Previous studies show that BICs in photonic crystal slabs are protected by C2TC_{2}T symmetry and hence normally exist on the high-symmetry lines of momentum space. Here, we propose an approach based on graph theory to study these polarization singularities in momentum space, especially in the region off the high-symmetry lines. With a polarization graph, it is demonstrated for the first time that BICs can stably exist off the high-symmetry lines of momentum space for both one-dimensional and two-dimensional photonic crystal slabs. Furthermore, two kinds of interesting processes, including the merging involved with this newly found BICs both on and off the high-symmetry lines, are observed by merely changing the thickness of photonic crystal slab. Our findings provide a new perspective to explore polarization singularities in momentum space and render their further applications in light-matter interaction and light manipulation.Comment: 18 pages,8 figure

    Quantum Anomalous Hall Effect in Graphene from Rashba and Exchange Effects

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    We investigate the possibility of realizing quantum anomalous Hall effect in graphene. We show that a bulk energy gap can be opened in the presence of both Rashba spin-orbit coupling and an exchange field. We calculate the Berry curvature distribution and find a non-zero Chern number for the valence bands and demonstrate the existence of gapless edge states. Inspired by this finding, we also study, by first principles method, a concrete example of graphene with Fe atoms adsorbed on top, obtaining the same result.Comment: 4 papges, 5 figure

    High-Speed Railway Tunnel Hood: Seismic Dynamic Characteristic Analysis

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    When a high‐speed train is passing through a tunnel, micro‐compression wave may be created at the tunnel exit, which will affect the environment around the railway line. Setting hood at tunnel entrance is one of the efficacious ways for solving this problem. While in an earthquake region, in addition to consideration of controlling micro‐compression wave, the seismic safety of hood structure must not overlook the factor. In this chapter, using finite difference method, several types of hood seismic dynamic characteristic were analyzed, and their seismic dynamic respond stress curves were drawn out. As a result, the recommended hood type was determined, which is helpful for hood design in high intensity earthquake zone

    Dopamine D1 receptor-mediated NMDA receptor insertion depends on Fyn but not Src kinase pathway in prefrontal cortical neurons

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    <p>Abstract</p> <p>Background</p> <p>Interactions between dopamine and glutamate in the prefrontal cortex are essential for cognitive functions such as working memory. Modulation of N-methyl-D-aspartic acid (NMDA) receptor functions by dopamine D1 receptor is believed to play a critical role in these functions. The aim of the work reported here is to explore the signaling pathway underlying D1 receptor-mediated trafficking of NMDA receptors in cultured rat prefrontal cortical neurons.</p> <p>Results</p> <p>Activation of D1 receptor by selective agonist SKF-81297 significantly increased the expression of NR2B subunits. This effect was completely blocked by small interfering RNA knockdown of Fyn, but not Src. Under control conditions, neither Fyn nor Src knockdown exhibited significant effect on basal NR2B expression. D1 stimulation significantly enhanced NR2B insertion into plasma membrane in cultured PFC neurons, a process obstructed by Fyn, but not Src, knockdown.</p> <p>Conclusions</p> <p>Dopamine D1 receptor-mediated increase of NMDA receptors is thus Fyn kinase dependent. Targeting this signaling pathway may be useful in treating drug addiction and schizophrenia.</p

    Two-dimensional photonic crystal polarizer

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    A novel polarizer made from two-dimensional photonic bandgap materials was demonstrated theoretically. This polarizer is fundamentally different from the conventinal ones. It can function in a wide frequency range with high performance and the size can be made very compact, which renders it useful as a micropolarizer in microoptics.Comment: 8 pages, RevTex, 4 figure
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