2 research outputs found
Self-Cross-Linking Degradable Polymers for Antifouling Coatings
Degradable
polymers with protein resistance can find applications
in antibiofouling. We have prepared copolymer of 2-methylene-1,3-dioxepane
(MDO), 2-(dimethylamino) ethyl methacrylate (DEM) and 3-(methacryloxypropyl)
trimethoxysilane (KH570) via radical ring-opening polymerization,
where MDO, DEM, and KH570 make the polymer degradable, protein resistant
and self-cross-linkable, respectively. Our studies demonstrate that
the self-cross-linking significantly improves the coating ability
of the polymer with controlled biodegradation in seawater. We have
investigated the adsorption of fibrinogen, bovine serum albumin and
lysozyme on the self-cross-linking polymer surface as a function of
its composition by use of quartz crystal microbalance with dissipation
(QCM-D). It shows the polymer network can resist the adsorption of
proteins in seawater. The antibacterial adhesion of the polymer network
was evaluated by using <i>Micrococcus luteus</i> (<i>M. luteus</i>) and <i>Pseudomonas</i> sp., revealing
that the polymer network can effectively inhibit the settlement of
marine bacteria
Biodegradable Polymer with Hydrolysis-Induced Zwitterions for Antibiofouling
Persistent protein
resistance is critical for marine antibiofouling. We have prepared
copolymer of 2-methylene-1,3-dioxepane (MDO), tertiary carboxybetaine
ester (TCB), and 7-methacryloyloxy-4-methylcoumarin (MAMC) via radical
ring-opening polymerization, where MDO, TCB, and MAMC make the polymer
degradable, protein resistible, and photo-cross-linkable, respectively. Our study shows that the polymer can well adhere to the substrate
with controlled degradation and water adsorption rate in artificial
seawater (ASW). Particularly, the polymer film can generate zwitterions
via surface hydrolysis in ASW. Quartz crystal microbalance with dissipation
measurements reveal that such hydrolysis-induced zwitterionic surface
can effectively resist nonspecific protein adsorption. Moreover, the
surface can inhibit the adhesion of marine bacteria <i>Pseudomonas</i> sp. and Vibrio alginolyticus as well
as clinical bacterium Escherichia coli