1 research outputs found
N‑Heterocyclic Carbene-Catalyzed Convenient Benzonitrile Assembly
The
benzonitrile unit is widely found in natural products, pharmaceuticals,
and agrochemicals. Synthesis of benzonitriles has received considerable
interests from the chemical community over the last few decades. Present
synthetic protocols mainly rely on the pre-existing benzene core to
install a cyano moiety. A new NHC-catalyzed [4 + 2]-benzannulation
protocol is reported to assemble the benzonitrile framework