Exploring the communication effects of signals and messages in the COVID-19 health crisis

The ongoing coronavirus disease 2019 (COVID-19) pandemic presents an unprecedented global public health crisis. In this scenario, crisis communication on social media that largely influences people’s emotions, attitudes and interaction behaviours towards a large-scale public health crisis plays a critical role in persuading the public’s behaviour adjustment and coping with the risk. The effects of crisis communication strategies and signals embedded in social media topics and messages warrant further investigation. This study explored and tested the communication effects of crisis messages and topics from the initial event stage to the normalized control stage of the COVID-19 crisis using texts scraped from a Chinese social media website, namely Weibo. Natural language processing (NLP) techniques, i.e., sentiment and emotion analysis, positivist text coding, and ordinary least squares (OLS) were used in data analysis. This study contributes to the crisis management literature and theories by identifying and testing a number of factors and signals in crisis communication on social media that influence receivers’ reactions and behaviours. In doing so, this study provides suggestions for practitioners and policymakers on effective communication of the crisis situation and prevention behaviours to the public

Diquarks and the Semi-Leptonic Decay of Λb\Lambda_{b} in the Hybrid Scheme

In this work we use the heavy-quark-light-diquark picture to study the semileptonic decay $\Lambda_b \to \Lambda_c+l+\bar{\nu}_l$ in the so-called hybrid scheme. Namely, we apply the heavy quark effective theory (HQET) for larger $q^2$ (corresponding to small recoil), which is the invariant mass square of $l+\bar\nu$, whereas the perturbative QCD approach for smaller $q^2$ to calculate the form factors. The turning point where we require the form factors derived in the two approaches to be connected, is chosen near $\rho_{cut}=1.1$. It is noted that the kinematic parameter $\rho$ which is usually adopted in the perturbative QCD approach, is in fact exactly the same as the recoil factor $\omega=v\cdot v'$ used in HQET where $v$, $v'$ are the four velocities of $\Lambda_b$ and $\Lambda_c$ respectively. We find that the final result is not much sensitive to the choice, so that it is relatively reliable. Moreover, we apply a proper numerical program within a small range around $\rho_{cut}$ to make the connection sufficiently smooth and we parameterize the form factor by fitting the curve gained in the hybrid scheme. The expression and involved parameters can be compared with the ones gained by fitting the experimental data. In this scheme the end-point singularities do not appear at all. The calculated value is satisfactorily consistent with the data which is recently measured by the DELPHI collaboration within two standard deviations.Comment: 16 pages, including 4 figures, revtex

A statistical method (cross-validation) for bone loss region detection after spaceflight.

Astronauts experience bone loss after the long spaceflight missions. Identifying specific regions that undergo the greatest losses (e.g. the proximal femur) could reveal information about the processes of bone loss in disuse and disease. Methods for detecting such regions, however, remains an open problem. This paper focuses on statistical methods to detect such regions. We perform statistical parametric mapping to get t-maps of changes in images, and propose a new cross-validation method to select an optimum suprathreshold for forming clusters of pixels. Once these candidate clusters are formed, we use permutation testing of longitudinal labels to derive significant changes

Methological quality of systematic reviews and meta-analyses on acupuncture for stroke: a review of review

Objective: To assess the methodological quality of systematic reviews and meta-analyses regarding acupuncture intervention for stroke and the primary studies within them. Methods: Two researchers searched PubMed, Cumulative index to Nursing and Allied Health Literature, Embase, ISI Web of Knowledge, Cochrane, Allied and Complementary Medicine, Ovid Medline, Chinese Biomedical Literature Database, China National Knowledge Infrastructure, Wanfang and Traditional Chinese Medical Database to identify systematic reviews and meta-analyses about acupuncture for stroke published from the inception to December 2016. Review characteristics and the criteria for assessing the primary studies within reviews were extracted. The methodological quality of the reviews was assessed using adapted Oxman and Guyatt Scale. The methodological quality of primary studies was also assessed. Results: Thirty-two eligible reviews were identified, 15 in English and 17 in Chinese. The English reviews were scored higher than the Chinese reviews (P=0.025), especially in criteria for avoiding bias and the scope of search. All reviews used the quality criteria to evaluate the methodological quality of primary studies, but some criteria were not comprehensive. The primary studies, in particular the Chinese reviews, had problems with randomization, allocation concealment, blinding, dropouts and withdrawals, intent-to-treat analysis and adverse events. Conclusions: Important methodological flaws were found in Chinese systematic reviews and primary studies. It was necessary to improve the methodological quality and reporting quality of both the systematic reviews published in China and primary studies on acupuncture for stroke

In vitro propagation and homing of liver-derived dendritic cell progenitors to lymphoid tissues of allogeneic recipients: Implications for the establishment and maintenance of donor cell chimerism following liver transplantation

Dendritic cell (DC) progenitors were propagated in liquid culture from nonparenchymal cells resident in normal mouse (B10.BR; H-2k, I-E+) liver in response to granulocyte-macrophage colony stimulating factor (GM-CSF). The liver-derived DC progenitors were MHC class II-/dim and did not express counter receptors for CTLA-4, a structural homologue of the Т cell activation molecule CD28. Following subcutaneous or intravenous injection, these liver-derived cells migrated to Т cell-dependent areas of lymph nodes and spleen of unmodified, allogeneic (BIO; H-2b; I-E_) recipients, where they were identified 1-5 days, and 1 and 2 months after injection by their strong surface expression of donor MHC class II (I-Ek) and their dendritic morphology. Maximal numbers of liver-derived DC in the spleen were recorded 5 days after injection. Both clusters of strongly donor MHC class II+ cells— and (more rarely) dividing cells—could also be identified, suggesting cell replication in situ. Using the same techniques employed to generate DC progenitors from normal liver, GM-CSF-stimulated cells were propagated for 10 days from the bone marrow and spleen of nonimmunosuppressed mice sacrificed 14 days after orthotopic liver transplantation (B10;H-2b → C3H;H-2k). Immunocytochemical staining for recipient and donor MHC class II phenotype revealed the growth both of host cells with DC characteristics, and of cells expressing donor alloantigens (I-Ab). These results are consistent with the growth, in response to GM-CSF, of donor-derived DC from progenitors seeded from the liver allograft to recipient lymphoid tissue. The functional activity of the progenitors of chimeric DC and the possible role of these cells in the establishment and maintenance of donor-specific tolerance following liver transplantation remain to be determined. © 1995 by Williams and Wilkins