Stimulus.

<p>A) Face exemplars for four versions of part tasks that (i) either have veridical face configurations or do not, and (ii) either contain full-spectrum spatial frequencies, or contain only high spatial frequencies. Within each version of the part task, either the two eyes or the mouth are changed. B) Face stimuli for the spacing task. C) Face stimuli for whole-part task.</p

Ultrasonic inspection of near surface defects with additive manufactured metasurface lens

Acoustic metasurfaces have been increasingly explored in the past 10 years because of their compact structure and wave manipulation capabilities. In this work, we explore the feasibility of using an acoustic metasurface lens (MSL) for the characterization of near surface defects in NDT. First, we delimited the design space for a MSL operating at 100 kHz, in terms of spatial footprint and materials, and then realized a library of labyrinthine cells optimized for transmission. Then, we assembled the unit cells into lens and simulated its performance in a hole inspection process. The time-domain simulations predicted an increase in scattering and interface effects but, thanks to the focusing behavior, they also showed a much lower drop in the peak amplitude (20%, compared to 70% without MSL). Finally, we validated the simulations using a UTR9000-based MSL on an acrylic sample. Experiments with the MSL showed a converging energy profile, reduced to half of its width without the lens, and the presence of additional transmission peaks allowed to determine the defect diameter with excellent precision, thus circumventing near surface interference. Our study may be the first step towards flexible beam control systems based on a single transducer.</p

Behavioral results from prosopagnosic subjects.

<p>A) Whole-part effect from the normal (Control) and prosopagnosic (DP) groups. B) The application of the standard and modified part-tasks in measuring how face parts are processed in prosopagnosia (DP).</p

Behavioral results from normal subjects.

<p>A) Face inversion effect (FIE) for featural information when the first-order face configuration is either preserved (Veridical) or disturbed (Scrambled). Accuracy is shown on the y-axis and the error bar stands for standard error. B) Face inversion effect for featural information when face stimuli are high-pass-filtered. C) Face inversion effect for configural information in the spacing task. D) Correlation across subjects between the configural effect in the part task and the FIE of the spacing task.</p

Phase behavior at Different Temperatures of an Aqueous Two-Phase Ionic Liquid Containing ([BPy] NO₃ + Ammonium Sulfate and Sodium Sulfate + Water)

Phase diagrams of aqueous two-phase systems composed of <i>N</i>-butylpyridinium nitrate + salt (ammonium sulfate and sodium sulfate) + water determined at (298.15, 308.15, 318.15 and 328.15) K. The binodal curves were associated with the Merchuk expression and another two empirical expressions. The influences of temperature and the type of cations were also studied, which demonstrated that lower temperature led to the expansion of the two-phase region, whereas the salting-out abilities of Na₂SO₄ exceeded that of (NH₄)₂SO₄, which was proven by the Gibbs free energy of hydration of the ions

Searchlight Analyses.

<p>A cluster of voxels in the right M1 show the increased stability of the activation pattern for the trained sequence (MNI coordinates: x = 52; y = −18; z = 58; t value = 4.76). The inset figure shows the overlap between the cluster identified by the searchlight analysis and the M1 identified in the localizer scan (outlined in cyan).</p

Increased USP42 expression correlated with poor survival of patients with GC.

<p>A. The mRNA levels of USP42 relative to GAPDH expression in GC and non-tumorous tissues were determined using real-time PCR (<i>P</i><0.0001). B. The expression of USP42 in GC and normal tissues based on TCGA dataset (<i>P</i><0.0001). C. Survival analysis showed that patients with USP42-higher expression tumors have a lower overall survival than those with USP42-lower expression tumors (<i>P</i> = 0.0141). D. Survival analysis on GSE26253 dataset.</p

Knockdown of USP42 expression inhibited GC cell proliferation <i>in vivo</i>.

<p>A. Tumor volume was measured after USP42 siRNA (siRNA) or siRNA control (siNC) injection. B. Mice were sacrificed and tumors were recovered at 36 days after tumor placement. The pictures (upper panel) and weight (n = 6, expressed as mean ± SD, lower panel) of recovered tumors were shown. C. The expression of USP42 and PCNA in tumors from the nude mice was determined by western blot. * <i>P</i><0.05, ** <i>P</i><0.01, *** <i>P</i><0.001 compared with siNC.</p

Correlation of USP42 expression with patients’ features in gastric cancer.

<p>Correlation of USP42 expression with patients’ features in gastric cancer.</p

USP42 silencing induced G0/G1 phase arrest.

<p>A. GSEA analysis in GC patients with higher USP42 expression versus lower USP42 expression based on TCGA datasets. KEGG cell cycle pathway was associated with USDP42-higher expression. The enrichment score (ES, green line) reflects the correlation between cell cycle pathway and the sample. Black bars indicate previously known genes associated with cell cycle pathway. B. USP42 silencing induced a G0/G1 arrest in GC cells. FACS histograms and cell-cycle analysis of AGS and MKN-5 cells. Quantification of the percentage of cells in G0/G1, S, and G2/M phase was shown. C. Expression of key proteins in cell cycle was determined by western blot. All assays were performed in triplicate. * <i>P</i><0.05, ** <i>P</i><0.01, *** <i>P</i><0.001 compared with siNC.</p