13 research outputs found

    Kaplan–Meier analysis of DFS and OS as a function of TET3 and TDG expression.

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    <p>The levels of TET3 and TDG mRNAs correlated inversely with DFS in patients treated with anthracyclines. Higher levels of TET3 and TDG mRNAs correlated with better DFS (P = 0.026 and 0.030, respectively).</p

    Primers used for real-time PCR analysis.

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    <p>Primers used for real-time PCR analysis.</p

    Kaplan–Meier analysis of DFS and OS as a function of TET1 mRNA levels.

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    <p>A. The DFS and OS of all patients were 0.521 and 0.745, respectively. B. Correlation between TET1-3 and TDG mRNAs with DFS and OS in 162 EBC patients. Higher level of TET1 mRNA was related to better OS (P = 0.022) (log-rank test).</p

    Clinicopathological characteristics of patients.

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    <p>Clinicopathological characteristics of patients.</p

    Additional file 1: Table S1. of MicroRNA-200a confers chemoresistance by antagonizing TP53INP1 and YAP1 in human breast cancer

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    List of primer and siRNA sequences. Table S2: Intersection between predict target of miR-200a and p53 family binding partner. (DOCX 17 kb

    Bamboo-Inspired, Environmental Friendly PDMS/Plant Fiber Composites-Based Capacitive Flexible Pressure Sensors by Origami for Human–Machine Interaction

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    With the widespread adoption of green and sustainable development concepts, enhancing the sensing performance of flexible pressure sensors while reducing manufacturing costs and environmental pollution has emerged as a pressing research issue. Drawing inspiration from bamboo, a naturally occurring green plant, we utilized virgin bamboo pulp as the raw material for producing draw paper. The resulting bamboo cylinder structure serves as the dielectric layer. We propose an extremely low-cost, user-friendly, and sustainable origami method for fabricating paper-based sensors. The structural parameters of the sensor were thoroughly investigated and optimized through finite element simulations and practical experiments. Notable features of the sensor include high sensitivity (1.96 kPa–1 within 0–50 kPa), a low detection limit (2 Pa), a wide pressure detection range (0–500 kPa), rapid response and recovery times (40 and 45 ms, respectively), and reliable durability and stability (∼5000 cycles). Experimental results demonstrate the successful application of these sensors in areas such as human motion, health monitoring, and human–computer interaction. The potential applications of sensors extend to flexible wearables, smart healthcare, human–machine collaboration, and electronic skin (e-skin)

    Flexible Capacitive Pressure Sensor with High Sensitivity and Wide Range Based on a Cheetah Leg Structure via 3D Printing

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    Flexible pressure sensors can be used in human–computer interaction and wearable electronic devices, but one main challenge is to fabricate capacitive sensors with a wide pressure range and high sensitivity. Here, we designed a capacitive pressure sensor based on a bionic cheetah leg microstructure, validated the benefits of the bionic microstructure design, and optimized the structural feature parameters using 3D printing technology. The pressure sensor inspired by the cheetah leg shape has a high sensitivity (0.75 kPa–1), a wide linear sensing range (0–280 kPa), a fast response time of roughly 80 ms, and outstanding durability (24,000 cycles). Furthermore, the sensor can recognize a finger-operated mouse, monitor human motion, and transmit Morse code information. This work demonstrates that bionic capacitive pressure sensors hold considerable promise for use in wearable devices
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