Epithelioid hemangiosarcomas of the bovine urinary bladder: a histologic, immunohistochemical, and ultrastructural examination of four tumors.

Epithelioid hemangiosarcoma is a specific variant of hemangiosarcoma that has recently been recognized in domestic animals. These malignant vascular neoplasms histologically resemble, and may be mistaken for, carcinomas. Four epithelioid hemangiosarcomas in the urinary bladders of 4 cows with severe enzootic hematuria are described in the current study. Grossly, the vesicular mucosa of the urinary bladder of each cow contained a single red elevated nodule. Histologically, each neoplasm was composed of short strands, cords, or nests of epithelioid, round, or slightly spindle-shaped endothelial cells that formed small vascular structures. Neoplastic cells were immunohistochemically positive for factor VIII–related antigen and vimentin, and were negative for cytokeratin and desmin. Ultrastructurally, the neoplastic cells often contained cytoplasmic intermediate filaments, a prominent granular endoplasmic reticulum, a Golgi complex, mitochondria, marked pinocytotic activity, and rare Weibel-Palade bodies. These neoplasms were diagnosed as epithelioid hemangiosarcomas based on their histologic, immunohistochemical, and ultrastructural features. The present report widens the spectrum of mesenchymal tumors of the bovine urinary bladder and aids in the characterization of these vascular neoplasms

Características físico-químicas e perfil lipídico do leite de cabras mestiças Moxotó alimentadas com dietas suplementadas com óleo de semente de algodão ou de girassol Physico-chemical characteristics and fatty acid profile of milk of crossbred Moxotó goats supplemented with cottonseed or sunflower oil

O efeito da suplementação com óleos de algodão e de girassol sobre a composição do leite foi testado em cabras mestiças Moxotó alimentadas com cinco dietas: controle, sem adição de óleo; adição de óleo de algodão a 3%; óleo de algodão a 5%; óleo de girassol a 3%; e óleo de girassol a 5% (%MS). Foram utilizadas dez cabras em lactação, confinadas, distribuídas em dois quadrados latinos (5 &times; 5), com 12 dias de adaptação e três dias de coleta em cada período. A suplementação com óleo de algodão a 5% MS elevou o teor de gordura (4,99%) e de extrato seco total (13,48%) do leite, mas não alterou a concentração dos demais componentes. A adição de 5% de óleo de girassol, no entanto, promoveu aumento na concentração do ácido linolênico (C18:3). A adição de óleo vegetal em dietas para cabras nativas promoveu aumento do percentual de gordura no leite e aumento nos teores de ácidos graxos insaturados resultando em um produto de melhor qualidade para a saúde humana.<br>The effects of cottonseed and sunflower oil supplementation on milk composition were tested using crossbred Moxotó goats. Experimental diets were as follows: control, without addition of oil; addition of 3% cottonseed oil; 5% cottonseed oil; 3% sunflower oil and 5% sunflower oil (%DM). Ten confined lactating goats were allotted to a double Latin square experimental design (5 &times; 5). Each period was comprised by 12 days of adaptation to the diet and three days of sampling in each period. Cottonseed oil supplementation at 5 %DM increased the fat content (4.99%) and the total solid (13.48%) of milk. However, the addition of sunflower oil at 5% promoted an increase in the linolenic acid (C18:3) concentrations. Therefore, the vegetal oil addition in diets for native goats promoted an increase in the percentage of milk fat and in unsaturated fatty acid contents in milk, resulting in a product of better quality for the human health