Estimating infarct severity from the ECG using a realistic heart model

The early phase of myocardial infarction is accompanied by changes in the ST segment of the ECG. This makes the ST segment the clinical marker for the detection of acute myocardial infarction. The determination of the infarct severity, location and size of the myocardial tissue at risk will support clinical decision making. In this study we used an inverse procedure to estimate the location and size of the infarcted heart region. The method estimates the local transmembrane amplitude based on the ECG amplitude near the J-point of the standard 12 leads signals using a patient specific volume conductor model. For the 5 available patient cases the positions as well as the size of the estimated infarct region were in accordance with results based on MRI

Validation of infarct size and location from the ECG by inverse body surface mapping

This paper describes the incorporation of body surface mapping algorithms to detect the position and size of acute myocardial infarctions using standard 12 lead ECG recording. The results are compared with the results from cardiac MRI scan analysis. In case patient specific volume conductor models are used, the position of the infarction could be accurately determined. When generalized patient volume conductor models were examined, the estimation of the infarct position became significantly less accurate. The calculations of the size of the infarctions need further improvement

Motor activation in people with profound intellectual and multiple disabilities in daily practice

Background People with profound intellectual and multiple disabilities (PIMD) are at risk of being motorically inactive. This study investigated the degree and type of motor activation in daily practice and its relationship to personal and contextual factors. Method A total of 58 participants with PIMD participated in the study. Data concerning the motor activation were collected by means of a diary over a period of 14 days. Relationships to personal and contextual factors were analysed using multilevel analyses. Results The mean number of transfers was 3.1 times per day (range: 0¬–9, SD = 1.4), the mean number of relocations was 7.7 times per day (range: 2–13, SD = 2.5), the mean number of motor activities offered was 1.5 per day (range: 0–10, SD = 1.9). Relationships to age, gender, location and day of week were found. Conclusion Motor activation seems to be a minor part of the support provided to people with PIMD

Degree and type of motor activation in daily practice:A study in people with profound intellectual and multiple disabilities

People with profound intellectual and multiple disabilities (PIMD) are at risk of being motorically inactive. This study investigated the degree of motor activation in people with PIMD in daily practice and its relationship to personal and contextual factors. A total of 58 participants with PIMD participated in thisstudy. Data on motor activation were collected by means of a diary. Relationships with personal and contextual factors were analyzed using multilevel analyses. The mean number of transfers was 3.1 times per day (range: 0–9, SD = 1.4), the mean number of relocations was 7.7 times per day (range: 2–13, SD = 2.5), the mean number of motor activities offered was 1.5 per day (range: 0–10, SD = 1.9). Relationships with age, gender, location and day of week were found. Motor activation seems to be a minor part of the support provided to people with PIMD