Validation of PARADISE 24 and Development of PARADISE-EDEN 36 in Patients with Dementia

Dementia was one of the conditions focused on in an EU (European Union) project called “PARADISE” (Psychosocial fActors Relevant to brAin DISorders in Europe) that later produced a measure called PARADISE 24, developed within the biopsychosocial model proposed in the International Classification of Functioning Disability and Health (ICF). The aims of this study are to validate PARADISE 24 on a wider sample of patients with mild to moderate dementia to expand PARADISE 24 by defining a more specific scale for dementia, by adding 18 questions specifically selected for dementia, which eventually should be reduced to 12. We enrolled 123 persons with dementia, recruited between July 2017 and July 2019 in home care and long-term care facilities, in Italy, and 80 participants were recruited in Warsaw between January and July 2012 as part of a previous cross-sectional study. The interviews with the patient and/or family were conducted by health professionals alone or as a team by using the Paradise data collection protocol. The psychometric analysis with the Rasch analysis has shown that PARADISE 24 and the selection of 18 additional condition-specific items can be expected to have good measurement properties to assess the functional state in persons with dementia

Composição corporal e exigências de proteína para ganho de peso de caprinos Moxotó em crescimento Body composition and protein requirements for weight gain of growing Moxotó kids

Avaliaram-se a composição corporal e as exigências de proteína para ganho de peso de caprinos da raça Moxotó. Utilizaram-se 26 animais machos não-castrados, com peso vivo (PV) médio inicial de 15 kg e 7 a 8 meses de idade, alimentados com dieta contendo 2,6 Mcal de energia metabolizável. Ao início do experimento, seis animais foram abatidos e serviram como referência para estimativa da composição corporal e do peso de corpo vazio (PCVZ) iniciais. Posteriormente, formaram-se grupos homogêneos de quatro animais, distribuídos ao acaso em dois programas de alimentação (tratamentos): alimentação à vontade (AV); e restrição alimentar de 85, 70 e 55% do consumido pelo grupo com alimentação à vontade. Os animais com AV foram abatidos no momento em que o PV se aproximou de 25 kg. As equações do logaritmo (log) dos conteúdos corporais de proteína (CCP) foram ajustadas considerando o log do PCVZ. Derivando-se essa equação, obteve-se a equação de predição do conteúdo de proteína por kg de ganho de PCVZ. Os conteúdos protéicos dos animais experimentais mantiveram-se praticamente constantes e variaram de 205,60 para 201,69 g/kg de PCVZ (redução de 1,9%) e de 15 para 25 kg com o aumento do PV. Apesar da pouca variação corporal das exigências líquidas protéicas (19,86 para 19,49), a relação gordura:proteína aumentou com o aumento do PV de 15 para 25 kg.<br>Twenty-six Moxotó non-castrated male kids (initial mean 15 kg LW and 7-8 month old) fed a diet with 2.6 Mcal ME were used to evaluate the body composition and protein requirements for weight gain. At the beginning of the experiment, six animals were slaughtered as reference to estimate initial body composition and initial empty body weight (EBW). Subsequently, homogeneous groups of four animals were distributed a complete randomized experimental design into two feeding regimes: ad libitum feeding (AL) and feed restriction of 85, 70 and 55% of that consumed by the AL feeding group. The animals from each feeding regime were slaughtered at the time the group of the AL feeding approached 25 kg LW. Logarithm equation of retained body protein contents (BCP) was fitted on log10 of empty body weight (EBW). By deriving this equation, the predicting equation of BCP per kg of EBW gain was obtained. The protein content of the animals remained practically constant and ranged from 205.60 to 201.69 g/kg of EBW (reduction of 1.9%) and 15 to 25 kg with the increase of live weight. Despite of small body changes of net protein requirements (19.86 to 19.49), the fat: protein ratio increased with the increase in LV from 15 to 25 kg