Gastrointestinal stromal tumors stomach cese

Gastrointestinal stromal tumors (GIST omi) are a heterogeneous group of mesenchymal tumors. Etiological factors that cause GIST ome are not clearly distinguished, characterized by remarkable diversity of the clinical, histopathological and genetic features. Mitotic activity, nuclear pleomorphism, degree of cellularity, nuclear-cytoplasmic ratio, tumor size, mucosal invasion, tumor ulceration and necrosis, are factors that determine the malignancy of these tumors. The most common location of these tumors of the stomach and small intestine, while very rare localization of the colon, esophagus and rectum. Despite the progress that has been made in the diagnosis and further diagnosis of intra - or postoperative. The aim of this report is to contribute to easier recognizing the symptoms, diagnosis and treatment of these tumors. It was a mixed tumor, epitheloid-spindle type cells, immunohistochemical analysis, we have a positive expression of CD 117 and CD 34

Comparing the unified protocol for transdiagnostic treatment of emotional disorders to prolonged exposure for the treatment of PTSD: Design of a non-inferiority randomized controlled trial

Background: Prolonged Exposure (PE), a trauma-focused therapy, is one of the most efficacious treatments available for PTSD. However, many people with PTSD do not lose their diagnosis following delivery of PE. The Unified Protocol (UP) for Transdiagnostic Treatment of Emotional Disorders is a non-trauma focused treatment that may offer an alternative treatment for PTSD. Methods: This paper describes the study protocol for IMPACT, an assessor-blinded randomized controlled trial that examines the non-inferiority of UP relative to PE for participants who meet DSM-5 criteria for current PTSD. One hundred and twenty adult participants with PTSD will be randomized to receive either 10 × 90-min sessions of UP or PE with a trained provider. The primary outcome is severity of PTSD symptoms assessed by the Clinician Administered PTSD Scale for DSM-5 (CAPS-5) at post-treatment. Discussion: While evidence-based treatments are available for PTSD, high levels of treatment dropout and non-response require new approaches to be tested. The UP is based on emotion regulation theory and is effective in treating anxiety and depressive disorders, however, there has been limited application to PTSD. This is the first rigorous study comparing UP to PE in a non-inferiority randomized controlled trial and may help improve clinical outcomes for those with PTSD. Trial registration: This trial was prospectively registered with the Australian New Zealand Clinical Trials Registry, Trial ID (ACTRN12619000543189)