Pengaruh Jalan Pagi terhadap Perubahan Tekanan Darah pada Lanjut Usia dengan Hipertensi di Desa Kalianget Timur Kecamatan Kalianget Kabupaten Sumenep

Pendahuluan: Jalan pagi merupakan aktivitas ringan yang sesuai untuk orang dengan lanjut usia (lansia) karena dapat membantu mengendalikan tekanan darah dalam jangka panjang. Keterbatasan lansia untuk melakukan aktivitas fisik sehari-hari dapat mempengaruhi Perubahan tekanan darah. Penelitian ini bertujuan untuk menganalisis pengaruh jalan pagi terhadap Perubahan tekanan darah pada lansia dengan hipertensi. Metode: Desain penelitian pre-experiment menggunakan one group pre-post test design, dengan teknik simple random sampling. Populasi dalam penelitian adalah lansia dengan hipertensi di Desa Kalianget Timur sebanyak 71 orang, sampel sebanyak 60 orang. Analisa data menggunakan uji statistik Wilcoxon. Hasil: Hasil penelitian menunjukkan bahwa sebelum dilakukan jalan pagi sebagian besar (65%) tekanan darah sistole 140-159 mmHg dan tekanan darah diastole seluruhnya (100%) >100 mmHg. Kemudian sesudah dilakukan jalan pagi tekanan darah menurun, sebagian besar (55%) tekanan darah sistole 140-159 mmHg dan hampir seluruhnya (88,3%) tekanan darah diastole >100 mmHg. Hasil analisa data diperoleh p= 0,000

Dengue viral infection in Indonesia: Epidemiology, diagnostic challenges, and mutations from an observational cohort study.

BackgroundDengue virus (DENV) infection is a major cause of acute febrile illness in Indonesia. Diagnostic inaccuracy may occur due to its varied and non-specific presentation. Characterization of DENV epidemiology, clinical presentation, and virology will facilitate appropriate clinical management and public health policy.Methodology/principal findingsA multicenter observational cohort study was conducted in Indonesia to assess causes of acute fever requiring hospitalization. Clinical information and specimens were collected at enrollment, 14-28 days, and 3 months from 1,486 children and adults. Total of 468 (31.9%) cases of DENV infection were confirmed by reference laboratory assays. Of these, 414 (88.5%) were accurately diagnosed and 54 had been misdiagnosed as another infection by sites. One hundred initially suspected dengue cases were finally classified as 'non-dengue'; other pathogens were identified in 58 of those cases. Mortality of DENV infection was low (0.6%). Prior DENV exposure was found in 92.3% of subjects >12 years. DENV circulated year-round in all cities, with higher incidence from January to March. DENV-3 and DENV-1 were the predominant serotypes. This study identified DENV-1 with TS119(C→T) substitution in the serotyping primer annealing site, leading to failure of serotype determination.Conclusions/significanceDENV is a common etiology of acute febrile illness requiring hospitalization in Indonesia. Diagnostic accuracy at clinical sites merits optimization since misdiagnosis of DENV infection and over-estimation of dengue can negatively impact management and outcomes. Mutation at the annealing site of the serotyping primer may confound diagnosis. Clinicians should consider following diagnostic algorithms that include DENV confirmatory testing. Policy-makers should prioritize development of laboratory capacity for diagnosis of DENV