2 research outputs found

    Utilizaci贸n de matriz 贸sea esponjosa anorg谩nica bovina en un modelo experimental de reparaci贸n 贸sea

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    The dimensions of the alveolar bone surrounding the tooth are not maintained post tooth-extraction probably as a consequence of the bone remodeling process and the biomechanical demands on bone. The use of biomaterials as bone substitutes in the post-tooth-extraction socket promotes bone repair, regardless of damage to bone structures during the surgical procedures. The aim of the present study was to evaluate the effectiveness of anorganic bovine bone matrix (ABBM) as a bone substitute, in an experimental model of post-tooth extraction bone healing in the rat. Radiographic follow-up was performed at 7, 14, and 30 days, and showed persistence of the biomaterial inside the experimental alveoli. At 14 and 30 days post-tooth extraction, particles surrounded by bone tissue were observed in the middle sector of the alveoli. The osteoconductive property of ABBM was demonstrated using the present experimental model of active osteogenesis, thus showing its usefulness as a bone substitute. Persistence of the particles at the studied experimental time points did not affect post-tooth extraction bone healing.Las dimensiones del hueso alveolar que rodea a la pieza dentaria, no se mantienen despu茅s de la exodoncia. Este hecho seria consecuencia del proceso de remodelado 贸seo y del requerimiento biomec谩nico. La utilizaci贸n de biomateriales como sustitutos 贸seos en los alveolos, facilitan o promueven la reparaci贸n 贸sea, independientemente que se haya producido traumatismo de las estructuras 贸seas durante la maniobra quir煤rgica. El objetivo del presente estudio fue evaluar la efectividad de una matriz 贸sea esponjosa anorg谩nica (MOEA) como sustituto 贸seo, en un modelo experimental de reparaci贸n 贸sea en el alveolo post-extracci贸n en ratas. Se realizo el estudio radiogr谩fico en los distintos tiempos experimentales: 7, 14 y 30 dias, evidenciando la persistencia del biomaterial. A los 14 y 30 d铆as post-exodoncia se evidenciaron las part铆culas rodeadas de tejido 贸seo en el sector medio del alveolo. Es importante destacar que la utilizaci贸n de (MOEA), como sustituto 贸seo en el alveolo post-exodoncia de rata, evidencio su capacidad osteoconductiva. La persistencia de las part铆culas del biomaterial en los tiempos estudiados no interfiri贸 en la reparaci贸n 贸sea.Fil: Redondo, Marcela A.. Universidad de Buenos Aires. Facultad de Odontolog铆a; ArgentinaFil: Renou, Sandra Judith. Consejo Nacional de Investigaciones Cient铆ficas y T茅cnicas; Argentina. Universidad de Buenos Aires. Facultad de Odontolog铆a. C谩tedra de Anatom铆a Patol贸gica; ArgentinaFil: Puia, Sebastian A.. Universidad de Buenos Aires. Facultad de Odontolog铆a; ArgentinaFil: Costa, Osvaldo. Universidad de Buenos Aires. Facultad de Odontolog铆a; ArgentinaFil: Guglielmotti, Maria Beatriz. Consejo Nacional de Investigaciones Cient铆ficas y T茅cnicas; Argentina. Universidad de Buenos Aires. Facultad de Odontolog铆a. C谩tedra de Anatom铆a Patol贸gica; Argentin

    Effect of bismuth subgallate (a hemostatic agent) on bone repair; a histologic, radiographic and histomorphometric study in rats

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    Bismuth subgallate (BS) is a hemostatic agent used for soft tissue surgery in otorhinolaryngology and dermatology. Its effect on bone repair has not been studied. The present study undertook a quantitative and qualitative evaluation of post-extraction bone healing in the presence of BS. Under intraperitoneal anesthesia, forty male Wistar rats, 80 卤 5 g body weight, underwent the extraction of both lower first molars. BS was placed in the right post-extraction socket (group E) and the contralateral socket served as control (group C). The animals were killed in groups immediately, 7, 14 and 30 days post-extraction. The mandibles were resected, radiographed and processed for embedding in paraffin. The mesial socket was sectioned along the bucco-lingual axis and stained with hematoxylin-eosin. Total tissue volume and trabecular bone volume of the apical third of the sockets were determined histomorphometrically. At 14 and 30 days post-extraction, group E exhibited bone tissue that resembled that of group C. Histomorphometric analyses showed no statistically significant differences between groups C and E. Bismuth subgallate did not interfere with post-extraction bone healing. Further studies will analyze the effect of this hemostatic agent on bone repair in aniticoagulated rats.Fil: Puia, Sebastian A.. Universidad de Buenos Aires. Facultad de Odontolog铆a; ArgentinaFil: Renou, Sandra Judith. Universidad de Buenos Aires. Facultad de Odontolog铆a; ArgentinaFil: Rey, Eduardo A.. Universidad de Buenos Aires. Facultad de Odontolog铆a; ArgentinaFil: Guglielmotti, Maria Beatriz. Consejo Nacional de Investigaciones Cient铆ficas y T茅cnicas. Oficina de Coordinaci贸n Administrativa Houssay; Argentina. Universidad de Buenos Aires. Facultad de Odontolog铆a; ArgentinaFil: Bozzini, Carlos Eduardo Jose. Consejo Nacional de Investigaciones Cient铆ficas y T茅cnicas. Oficina de Coordinaci贸n Administrativa Houssay; Argentina. Universidad de Buenos Aires. Facultad de Odontolog铆a; Argentin
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