Triplet repeat density in <i>D. discoideum</i> exons.

<p>The inset shows the frequency distribution of triplet-repeat loci in exons of <i>D. discoideum</i>, grouped by the number of uninterrupted repeat units. The main figure histogram compares density of such exon repeats with other taxa, which were scored for triplet repeat of length 4 or higher in exons <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0046150#pone.0046150-Toth1" target="_blank">[39]</a>. The <i>D. discoideum</i> data include all loci with 5 or more repeats and is therefore slightly conservative.</p

Amino acid diversity of the genes <i>yakA</i>, <i>arg1</i> and <i>dimA</i>.

<p>The average amino acid diversity (or the average heterozygosity per amino acid position) was calculated for <i>D. discoideum</i> for <i>yakA</i>, <i>arg1</i> and <i>dimA</i> loci using only variation in numbers of amino acids in the assayed repeats. The value of Drosophila <i>Adh</i> locus is from Kreitman <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0046150#pone.0046150-Kreitman1" target="_blank">[40]</a> and Hartl <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0046150#pone.0046150-Hartl1" target="_blank">[41]</a>, and values of Human <i>HLA-A</i> and <i>HLA-B</i> loci are from Hedrick <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0046150#pone.0046150-Hedrick1" target="_blank">[27]</a>, both based on substitutions.</p

Gene diversity (expected heterozygosity) of microsatellites in the multiple-repeat and clone-rich samples.

<p>White bars show 8 microsatellites genotyped in the multiple-repeat sample, from the known genes <i>dimA</i>, <i>yakA</i> and <i>atg1</i>. Grey bars show the 8 microsatellite loci from the clone-rich sample of 316 clones. Error bars are 95% confidence intervals, estimated using 1000 bootstrap samples of individuals with replacement.</p

Average Gene diversity (expected heterozygosity) of the 8 triplet microsatellite loci in the multiple-repeat sample, divided by subpopulation.

<p>The error bars mark the bootstrap 95% confidence intervals, estimated using 1000 bootstrap samples of individuals with replacement.</p

The frequency distribution of genotypes of eight coding triplet repeats from the gene <i>dimA, yakA,</i> and <i>atg1</i>.

<p>These were genotyped from a sample of 115 clones isolated from various North American locations.</p