Nilai Rerata Vascular Pedicle Width, Vascular Pedicle-Cardiac Ratio Vascular Pedicle-Thoracic Ratio Orang Dewasa Normal Indonesia Studi Di RS Dr. Cipto Mangunkusomo

Vascular pedicle width (VPW) adalah jarak tepi luar vena kava superior ke tepi luar arteri subklavia kiri. Pemeriksaan VPW di foto toraks bersifat non-invasif, cepat dan mudah untuk memprediksi hipervolemia.Penelitian ini bertujuan untuk mengetahui rerata nilai VPW orang dewasa normal Indonesia. VPW diukurdengan dua metode: pertama pengukuran VPW tunggal yang akurasinya terbatas di foto toraks digital karenarelatif tidak dipengaruhi faktor magnifikasi. Metode kedua untuk foto toraks nondigital yaitu pengukuranrasio:vascular pedicle-cardiac ratio (VPCR) dan vascular pedicle-thoracic ratio (VPTR). Pengukuran serupadilakukan terhadap  topogram CT scan toraks AP terlentang dan CT scan toraks lalu dibandingkan akurasipengukuran di topogram dengan CT scan  toraks sebagai standar baku. Sampel terdiri atas 104 foto toraksPA subyek normal dan 103 CT scan  toraks subyek terpilih. Pada pemeriksaan toraks PA didapatkan rerata VPW 48,0±5,5mm, rerata VPCR 40,3±4,6%, dan rerata VPTR 17,2±1,7%. Pada pemeriksaan topogram CTscan didapatkan rerata VPW 50,3±6,2mm, rerata VPTR 45±5,1%, dan rerata VPTR 19,8±2,5%. Rerata VPWpada CT scan toraks 50,4±6,1mm. Pengukuran di foto toraks AP 10% lebih besar dibandingkan pada fototoraks PA dan pengukuranVPW di foto toraks terbukti memiliki akurasi  tinggi. Kata kunci: fototoraks, vascular pedicle width, vascular pedicle-cardiac ratio, vascular pedicle-thoracic ratio, hipervolemia.   The Mean Value of Vascular Pedicle Width, Vascular Pedicle-Cardiac Ratio,Vascular Pedicle-Thoracic Ratio of Normal Indonesian Adult Study In dr. Cipto Mangunkusomo Hospita

Comparison of Topical Nepafenac 0.1 % and Prednisolone Acetate 1% as an Anti-Inflammatory After Vitrectomy in Rhegmatogenous Retinal Detachment

Post-operative ocular inflammation is treated with topical steroids but with side effects. Nepafenac isan effective NSAID with minimal side effects. This study aims to compare effectiveness topical nepafenac0.1% (nepafenac) and prednisolone acetate 1% (prednisolone) post-pars plana vitrectomy (PPV) forrhegmatogenous retinal detachment (RRD). This is a prospective, single blind, randomized, single centerclinical study performed on December 2015 to May 2016 at dr. Cipto Mangunkusumo Hospital, Jakarta. Atotal of 46 eyes (n=46) with RRD underwent PPV were included and randomized to topical nepafenac (23eyes) or prednisolone 1% (23 eyes). The median of anterior chamber inflammation, scores of pain, centralmacular thickness (CMT), and intraocular pressure (IOP) were evaluated at day 1, followed by 1st, 2nd, and4th week post-surgery. Median anterior chamber inflammation was grade 2 (1-4) in prednisolone group andgrade 3 (0.5-4) in nepafenac group at day 1 (p>0.05). Number of cell of anterior chamber inflammation andpain perception were not significantly different between groups (p>0.05) on follow-up. At day 1, nepafenacand prednisolone groups showed median CMT of 206 μm (131-299) and 208 μm (129-451). At 4th week, meanCMT were 174.9±30.7μm in prednisolone and 185.5±50.1μm in nepafenac group (p>0.05). Post-operativetopical nepafenac was equal to prednisolone in reducing inflammation in eyes undergoing PPV. Nepafenaccould be an alternative for post-PPV in RRD

Fatty Liver and Its Associated Factors Among Breast Cancer Patients in Dharmais Cancer Hospital, Jakarta

Background: Fatty liver is frequently found during ultrasound (US) examination of breast cancer patients. It is not known how the association between breast cancer and fatty liver. This study was aimed to obtaine the prevalence of fatty liver in breast cancer patients and its association with clinical characteristics of the patients.Method: This was a cross-sectional study in Dharmais Cancer Hospital, Jakarta. Study subjects were breast cancer patients who came between January 2011 and December 2013. Fatty liver was assessed by using abdominal US and were grouped into mild, moderate, and severe. Clinical characteristics of the patients included age, body mass index (BMI), menopausal status, breast tissue density using Breast Imaging Reporting and Data System (BI-RADS), and immunohistochemical estrogen receptor (ER) status.Results: A total of 72 patients were enrolled during the study period with the mean age of 47.5 years. Fatty liver was found in 68 (94.4%) patients. Sixty (83.3%) patients had moderate-to-severe fatty liver. Patients with moderate-to-severe fatty liver had significantly higher BMI (26.9 ± 5.39 vs. 23.6 ± 4.05 kg/m2; p = 0.005). Fatty liver was not associated with the patient's age, menopausal status, and breast tissue density.Conclusion: This study showed that the prevalence of fatty liver in breast cancer patients is very high. Fatty liver shows significant association with obesity but is not associated with breast tissue density or estrogen receptor status

Efek Tetes Mata Kombinasi Sodium Hialuronat dan Hydroxypropyl-Guar terhadap Stabilitas Lapisan Air Mata pada Mata Kering Terkait Sindrom Sjögren

Penelitian ini bertujuan untuk menilai stabilitas lapisan air mata pada mata kering terkait sindrom Sjögren (SS) yang diberi terapi tetes mata kombinasi sodium hialuronat 0,1% (SH) dan hydroxypropyl (HP)-guar, atau monoterapi tetes mata sodium hialuronat (SH). Sebanyak 17 pasien SS dibagi dalam 2 kelompok. Kelompok pertama mendapat kombinasi SH dan HP-guar, kelompok kedua mendapat terapi SH. NIKBUT, Schirmer, skor pewarnaan okular, dan sitologi impresi, serta keluhan subjektif dinilai sebelum dan sesudah pemberian obat. Setelah terapi selama 28 hari, terdapat peningkatan median NIKBUT, Schirmer, skor pewarnaan okular, densitas sel Goblet, dan perbaikan keluhan subjektif pada mata kering terkait SS.The objectives of the study is to assess the stability of dry eye LAM associated with Sjögren syndrome (SS) during combination therapy of sodium hyaluronate 0.1% (SH) and hydroxypropyl (HP) -guar, or monotherapy sodium hyaluronic (SH). A total of 17 SS patients in this study were divided into 2 groups. The first group received a combination of SH and HP-guar while the second group received SH therapy. NIKBUT, Schirmer, ocular staining score, and impression cytology, as well as subjective complaints was assessed before and after drug administration. After 28 days of therapy, there was a median increase in NIKBUT, Schirmer, ocular staining scores, Goblet cell density, and subjective complaints on SS-related dry eyes

Kriteria Diagnosis Kanker Paru Primer Berdasarkan Gambaran Morfologi Pada CT Scan Toraks Dibandingkan Dengan Sitologi

Menetapkan komponen gambaran morfologi kanker paru primer pada CT scan toraks yang dapat dipakai sebagai kriteria diagnosis. Penelitian ini menggunakan desain cross sectional. Dalam kurun waktu Desember 2006 - Mei 2007 di RS. Persahabatan Jakarta dilakukan pemeriksaan CT scan toraks terhadap 28 pasien dengan gambaran klinis diduga kanker paru primer. DinilailO gambaran morfologi kanker paru pada CT scan toraks, setiap gambaran morfologi kanker dibandingkan dengan hasil sitologi CT guided TTNA sebagai baku emas. Terdapat 7 komponen morfologi kanker paru primer pada CT scan toraks yang mempunyai sensitivitas yang tinggi dalam diagnosis yaitu: ukuran tumor > 3 cm sensitivitas 95,7%, penyangatan s24 HU sensitivitas 82,6%, tepi irregular-spiculated sensitivitas 78,3%, lobulated sensitivitas 73,9%, air bronchograms sensitivitas 69,6%, ground glass opacity sensitivitas 65,2 % dan densitas heterogen sensitivitas 65,2%.Komponen morfologi ukuran tumor > 3 cm, penyangatan 24 HU, tepi irregular spiculated, lobulated, air bronchograms, ground glass opacity dan densitas heterogen mempunyai sensitivitas yang tinggi serta dapat dipakai sebagai kriteria diagnosis kanker paru primer pada CT scan toraks