Additional file 2: of The value of blood cytokines and chemokines in assessing COPD

Cross Sectional Associations by Subgroup Heat Map. (PDF 156 kb

Additional file 3: Table S3. of Serum IgG subclass levels and risk of exacerbations and hospitalizations in patients with COPD

Median and interquartile range related to each IgG subclass according to the presence or absence of corresponding IgG subclass deficiency in the merged dataset (MACRO and STATCOPE cohorts combined). (DOCX 15 kb

Additional file 5: Figure S2. of Serum IgG subclass levels and risk of exacerbations and hospitalizations in patients with COPD

Comparison of IgG subclass levels according to hospitalization status in MACRO – First cohort (left panel) and STATCOPE – Replication cohort (right panel) cohorts. Error bars represent 95% confidence interval. (DOCX 243 kb

Additional file 2: Table S2. of Serum IgG subclass levels and risk of exacerbations and hospitalizations in patients with COPD

Median and interquartile range related to each IgG subclass according to the presence or absence of corresponding IgG subclass deficiency in MACRO and STATCOPE cohorts. (DOCX 15 kb

Additional file 6: Table S4. of Serum IgG subclass levels and risk of exacerbations and hospitalizations in patients with COPD

Interactions between IgG subclass levels and inhaled steroid use at enrollment and use of systemic steroids in previous 12 months for both outcomes of interest (time to first exacerbation and time to first hospitalization). (DOCX 15 kb

Additional file 1: Table S1. of Azithromycin and risk of COPD exacerbations in patients with and without Helicobacter pylori

Patient characteristics according to Helicobacter pylori status and treatment. Table S2. Effect of Helicobacter pylori status at enrollment and treatment on the rates of exacerbation per person-year. Table S3. Comparison of the proportion of subjects that showed significant reduction in HP antibody level at 12 months in 113 COPD patients. Table S4. Effect of treatment on changes in CRP level from baseline to 3 months according to HP status. (DOCX 36 kb

Additional file 1: of Genome-wide association study of lung function and clinical implication in heavy smokers

Table S1. Association Results of the Top SNPs (P < 10− 4) with Post-bronchodilator FEV1/FVC. Table S2. Association Results of the Top SNPs (P < 10− 4) with Post-bronchodilator % Predicted FEV1.Table S3. Genotype Frequency of rs28929474 in SERPINA1 Stratified by GOLD Stages. Table S4. Prediction Models for Post-bronchodilator Lung Function Using Top 10 SNPs for Post-bronchodilator % Predicted FEV1.Figure S1. Joint analysis of the top10 SNPs for post-bronchodilator % predicted FEV1 in 1075 SPIROMICS non-Hispanic White smokers with COPD. (DOCX 141 kb

Additional file 2: of ROP: dumpster diving in RNA-sequencing to find the source of 1 trillion reads across diverse adult human tissues

Table S1. The effect of altering order of ROP step on the classification accuracy. Table S2. Concordance of targeted TCRB-Seq and ROP based on three TCGA samples from kidney renal clear cell carcinoma (KIRC). Table S4. RNA-seq datasets overview. Table S5. Genomic profile of unmapped reads reported for each dataset (S1, S2, S3). Table S6. Relative genomic abundance of microbial taxa at different levels of taxonomic classification after removal of reads with human origin (average over all samples of three tissues, performed for in-house RNA-Seqdata). Table S7. Genomic profile of unmapped reads across two SRA RNA-seq samples using ROP v1.0.8. Percentage for each category is calculated as a fraction from the total number of reads. (PDF 100 kb

Airway tree caliber heterogeneity and airflow obstruction among older adults. Supplemental data. Journal of Applied Physiology. Accepted on February 22, 2024

Supplemental data</p

Additional file 1: of ROP: dumpster diving in RNA-sequencing to find the source of 1 trillion reads across diverse adult human tissues

Supplementary methods. (PDF 789 kb