Crystal structure of 3-[(E)-2-(4-phenyl-1,3-thiazol-2-yl)hydrazin-1-ylidene]indolin-2-one

In the title molecule, C17H12N4OS, the thiazole ring forms a dihedral angle of 10.8 (2)° with the phenyl ring and an angle of 3.1 (3)° with the indole ring system [which has a maximum deviation of 0.035 (2) Å]. The dihedral angle between the planes of the phenyl ring and the indole ring system is 11.5 (1)°. An intramolecular N—H...O hydrogen bond is observed. In the crystal, pairs of N—H...O hydrogen bonds form inversion dimers with an R22(8) graph-set motif

Synthesis, characterization, fluorescence and biological studies of Mn(II), Fe(III) and Zn(II) complexes of Schiff bases derived from Isatin and 3-substituted-4-amino-5-mercapto-1,2,4-triazoles

<div><p>A series of Mn(II), Fe(III) and Zn(II) complexes have been synthesized with Schiff bases derived from isatin and 3-substituted-4-amino-5-mercapto-1,2,4-triazole. The elemental, spectroscopic (Infrared, nuclear magnetic resonance, ultraviolet-visible, fast atom bombardment-mass, fluorescence and electrochemistry) and magnetic studies suggested that the metal complexes possess octahedral geometry. The Schiff bases and their metal complexes exhibit fluorescent properties. The antimicrobial studies of Schiff bases and their metal complexes against various bacterial (<i>Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa</i> and <i>Bacillus subtilis</i>) and fungal (<i>Aspergillus niger</i>, and <i>Penicillium chrysogenum</i>) species by the minimum inhibitory concentration method revealed that the metal complexes possess more healing antibacterial activities than the Schiff bases. DNA cleavage property of Mn(II), Fe(III) and Zn(II) complexes revealed the important role of metal ion in the biological system.</p></div