Clinical evaluation of Varnya Lepa Sunscreen Lotion on Hyperpigmentation

Face Hyperpigmentation is one of major concern in both fair skinned and dark skinned individuals in our country. More exposure to UV radiations plays important role in skin damage hence, more susceptible to photodamage. The negative effects of solar radiation increase the chance of hyperpigmentation, sunburn erythema, suntan, skin cancer etc. In Ayurveda, Author has mentioned compound formulation i.e., Varnya-Lepa, drugs like Raktachandana (Pterocarpus santalinus Linn.), Manjistha (Rubia cordifolia Linn), Lodhra (Symplocos racemosa Roxb), Kustha (Saussurea lappa), Priyangu (Callicarpa macrophylla), Vatankura (Ficus benghalensis) and Masura (Lens culinaria Medic) improves Vyanga (hyperpigmentation) and enhances the complexion. Lepa is not convenient in present era. The common problems with Lepas are stains after applications, time consuming, less shelf life etc. Lotion are viscous semisolid preparations. They may be oil-in-water or water-in-oil type, easy to apply in unbroken skin without friction. Lotions contain water soluble bases and hence are more convenient to use. The present aim study the effect of Varnya Lepa sunscreen lotion on Hyperpigmentation as compared with standard Lactocalamine sunscreen lotion. Study was randomized Open label controlled clinical trial. In this, 20 patients were enrolled from OPD of KLE Ayurveda hospital Belagavi, based on inclusion and exclusion criteria. Assessment based on Grading parameters in skin dryness, Oily skin, Skin luster, MASI score. In Conclusion, Varnya Lepa sunscreen lotion is proved to be significant on hyperpigmentation when compared with Lactocalamine sunscreen lotion

Efficacy of Jatyadi, Madhughrita and honey tulle in wound management: a three-arm randomized controlled clinical trial

Background: Ayurveda underlines the significance of wounds and wound healing. Acharya Susruta has highlighted the need for shastiupakramas in the management of the wound. Even with a multitude of therapeutic concepts and formulations in Ayurveda, wound management has yet to gain acceptance. Objective: To evaluate the effect of Jatyadi tulle, Madhughrita tulle, and honey tulle in the management of Shuddhavrana (clean wound). Materials and methods: A three-arm randomized, parallel group, active-controlled, open-label clinical trial. Randomization was done through online random number generator software to allocate 45 patients treatment into three groups. Trial groups were treated with Jatyadi tulle (JT), Madhughrita tulle (MG), and control group was treated with Honey tulle (HT) for 10 days, and assessment was done on the 5th and 10th day. The wound was assessed using the Bates Jensen wound assessment tool, and the efficacy of the dressing material was assessed using the Worcestershire tissue viability team dressing assessment form. The study outcomes were early wound healing and clinical cure. Results: Within-group results were assessed using the Wilcoxon matched pairs test, and between-group results were assessed by Kruskal–Wallis ANOVA and Mann–Whitney U test. Significant results were obtained within-group (p value < 0.05) from day 0 and at various time points. The results between groups were found to be comparable; JT and MG were found to be significant in ease of application, removal, and patient comfort. No adverse drug events were identified throughout the study. Conclusion: JT and MG tulle have shown significant results in the management of shuddhavrana