5,268 research outputs found
Unparticle physics in diphoton production at the CERN LHC
We have considered the di-photon production with unparticle at LHC. The
contributions of spin-0 and spin-2 unparticle to the di-photon production are
studied in the invariant mass and other kinematical distributions, along with
their dependencies on the model dependent parameters. The signal corresponding
to the unparticle is significant for moderate coupling constant values.Comment: 17 pages, 15 eps figure
Glutathione S-Transferase activity and total thiol status in chronic alcohol abusers before and 30 days after alcohol abstinence
Background: Glutathione S Transferase (GST) has been involved in detoxification process in the liver and its activity has been shown to be increased in alcohol abusers. In the current work we measured the GST activity, total thiol status, AST, ALT, and direct bilirubin in chronic alcohol abusers before and 30 days after alcohol abstinence and lifestyle modification. Methods: Serum and urine GST activity and total thiol status were determined using spectrophotometric methods and serum transaminases were determined using clinical chemistry analyzer. Results: We found,significant increase in serum and urine GST (p<0.001), AST (p<0.001), ALT (p<0.001), and decrease in total thiol status (p<0.001) in chronic alcohol abusers. GST activity significantly decreased (p<0.001) and total thiol status were improved significantly (p<0.001) 30 days after alcohol abstinence and lifestyle modification. Conclusion: This study provides preliminary data to suggest the role of GST as prognostic indicator of alcohol abstinence with possible trend towards an improvement in liver function
CHITOSAN NANOBUBBLES DEVELOPMENT AND EVALUATION FOR THE DELIVERY OF SUNITINIB-AN ANTICANCER AGENT
Objective: In the current study, we introduced a novel method for creating Sunitinib nanobubbles by incorporating it into chitosan-shelled nanobubbles.
Methods: The Design Expert® programme randomly assigned around 13 experiments, and multiple regression analysis was used to statistically examine the data. The effect of the amount of sunitinib, amount of chitosan, amount of Epikuron 200, amount of palmitic acid and stirring speed, on percent encapsulation efficiency and drug load while maintain minimum particle size of nanobubbles as considered through a definitive screening plan. By placing limitations on the response parameters, the optimum formulation was created using a numerical optimization approach. The three improved formulations (Batch1 through Batch3) were assessed.
Results: The findings show that the nanobubbles particle size of 78.56-82.42 nm with an encapsulation efficiency of 68.48-69.56 % and loading capacity of 23.88-25.02%. The quantity of sunitinib released from nanobubbles was much larger (96.52 percent) than that from the sunitinib solution within 24 h, according to an in vitro release profile of the medication using ultrasonography. The hemolytic activity of the blank nanobubbles and sunitinib-loaded nanobubbles was measured to assess their safety up to a concentration of 10 mg/ml. With erythrocytes, drug-loaded nanobubbles had a good safety profile. FTIR, DSC studies indicated no chemical interactions, TEM images revealed nanobubbles size of 70-100 nm and stability studies shows no significant changes.
Conclusion: For contrast-enhanced tumour imaging and subsequent therapeutic administration, nanobubbles were found to be superior
Anomalous Raman scattering from phonons and electrons of superconducting FeSe
We report interesting anomalies in the temperature dependent Raman spectra of
FeSe measured from 3K to 300K in the spectral range from 60 to 1800
cm and determine their origin using complementary first-principles
density functional calculations. A phonon mode near 100 cm exhibits a
sharp increase by 5% in frequency below a temperature T ( 100
K) attributed to strong spin-phonon coupling and onset of short-range
antiferromagnetic order. In addition, two high frequency modes are observed at
1350 cm and 1600 cm, attributed to electronic Raman scattering
from ()to / -orbitals of Fe.Comment: 19 pages, 4 figures, 1 tabl
Effect of Muons on the Phase Transition in Magnetised Proto-Neutron Star Matter
We study the effect of inclusion of muons and the muon neutrinos on the phase
transition from nuclear to quark matter in a magnetised proto-neutron star and
compare our results with those obtained by us without the muons. We find that
the inclusion of muons changes slightly the nuclear density at which transition
occurs.However the dependence of this transition density on various chemical
potentials, temperature and the magnetic field remains quantitatively the same.Comment: LaTex2e file with four postscript figure
Wake-Driven Dynamics of Finite-Sized Buoyant Spheres in Turbulence
Particles suspended in turbulent flows are affected by the turbulence and at
the same time act back on the flow. The resulting coupling can give rise to
rich variability in their dynamics. Here we report experimental results from an
investigation of finite-sized buoyant spheres in turbulence. We find that even
a marginal reduction in the particle's density from that of the fluid can
result in strong modification of its dynamics. In contrast to classical spatial
filtering arguments and predictions of particle models, we find that the
particle acceleration variance increases with size. We trace this reversed
trend back to the growing contribution from wake-induced forces, unaccounted
for in current particle models in turbulence. Our findings highlight the need
for improved multi-physics based models that account for particle wake effects
for a faithful representation of buoyant-sphere dynamics in turbulence.Comment: 5 pages, 4 figures,
http://journals.aps.org/prl/abstract/10.1103/PhysRevLett.115.12450
Electronic structure of Fe (0-5 at. %) doped MoO2 thin films studied by resonant photoemission spectroscopy
The electronic structure of pulsed laser deposited Mo1-xFexO2 (x=0, 0.02 and
0.05) thin films has been investigated using resonant photoemission
spectroscopy near Mo-4p absorption edge. In all the samples a broad Fano- like
resonance peak at ~46 eV is observed in the whole area of the valence band
which indicates the contribution of the Mo-4d states in the entire valence band
region. The doping of Fe in these films leads to decrease in Mo 4d states
contributing to electronic states at lower binding energy region. In addition
to this, we also observe a shoulder at 4.9 eV in the valence band spectra of
doped samples. It is proposed that the origin of this shoulder is due to the Fe
hybridised states.Comment: 16 pages, 4 figures ,. J. Phys. Cond. Mat. (accepted
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