Laser induced elastico mechano luminescence of SrAl2O4 : Eu phosphor

When γ – irradiated elastic mechano luminescent materials SrAl2O4 : Eu are exposed to 1060 nm infrared pulse of nanosecond duration from CO2 laser, then stress produced in the crystals excites visible luminescence due to piezoelectric field in SrAl2O4 : Eu phosphor because they are non – centro symmetric.  In the present investigation SrAl2O4 : Eu crystals are given laser shocks and ML intensity recorded. During laser induced shocks, ML intensity increases linearly with stress and attains a peak value at a particular time and then decays exponentially with time. A theoretical approach has been proposed to explain the experimental results.&nbsp

Water users' association in Left Bank Canal of Baldeva Medium Irrigation Project: Farmers' experience

Water users' associationsCooperativesIrrigation programsBenefitsWater distributionMaintenance

Rupture uterus: a retrospective analytical study

Background: Over 500,000 women die each year due to complications of pregnancy and childbirth, a number that has remained relatively unchanged since 1990, when the first global estimates of the burden of maternal mortality were developed (WHO 2005). Objective of present study was to find out risk factors, management, related complications and associated maternal morbidity and mortality with rupture uterus.Methods: A retrospective analytical study was performed at Department of Obstetrics and Gynecology, PDU Medical College, Rajkot, Gujarat, India over a period of 3 years during 2014-2016. Evaluation of maternal age, parity, SE status, booking status, obstetric risk factors, duration of hospital stay, causes of rupture uterus, Management, intra-op and post-operative complications, maternal morbidity and mortality was done.Results: Total 29 cases of rupture uterus were found during study period. Most of them belong to age group of 21-30 (77.17%), Primipara (41.3%), Lower socioeconomic status (86.2%) and unbooked (65.52%) cases. Most common cause of rupture uterus was prolonged obstructed labor (51.72%) while scarred uterus (41.73%), transverse lie (3.44%) and injudicious use of oxytocin (3.44%) were others. In 16 cases obstetric Hysterectomy (55.17%) was performed while in 13 cases repair (44.82%) was done. We have found 2 cases of maternal death (6.89%) while study period with rupture uterus.Conclusions: Present retrospective analytical study has concluded that rupture uterus is a life threatening complication. Proper antenatal and intrapartum care, identification of high risk factors, promotion of skilled attendance at birth and institutional delivery are key factors in reduction and early diagnosis

STABILITY INDICATING HPLC METHOD FOR DETERMINATION OF VILAZODONE HYDROCHLORIDE

Objective: The aim and objective of this study was to develop and validate Stability Indicating HPLC method for determination of Vilazodone Hydrochloride.Methods: The method was carried out on a Phenomenex, C18 (250x4.6 mm, 5 µm) Column using a mixture of Acetonitrile: Water (50:50v/v), pH adjusted to 3.3 with Glacial Acetic Acid for separation. The flow rate was adjusted at 1 ml/min and Detection was carried out at 240 nm.Results: The retention time of vilazodone hydrochloride was found to be 2.3 min. The calibration curve was found to be linear in the range 25-75µg/ml with a correlation coefficient (R2=0.996). The limit of detection and limit of quantitation were found to be 4.78µg/ml and 14.48µg/ml respectively. The % recovery of vilazodone hydrochloride was found to be in the range of 98.21±0.08 % to 99.07±0.64%. The proposed method was successfully applied for the estimation of vilazodone hydrochloride in marketed tablet formulation.Vilazodone Hydrochloride was subjected to forced degradation under Acidic, Alkaline, Oxidation, Dry Heat and Photolytic degradation conditions. Vilazodone hydrochloride showed 3.12% degradation under acidic condition, 4.78% under alkaline condition, 7.8% under oxidation condition, 3.53% under dry heat condition and 4.9% under photolytic condition.Acid degradation impurity was identified and characterised by LC-MS/MS was found to be 1-(4-Penten-1-yl) piperazine having molecular weight 154.253 (m/z 155.08) and Molecular Formula C9H18N2.Conclusion: A simple, precise, rapid and accurate Stability Indicating HPLC method has been developed and validated for the determination of Vilazodone Hydrochloride in presence of its degradation products as per the ICH Guidelines.Â

Dynamic Query Forms for Non-Relational Database

With quick advancement of investigative databases and web data databases are turning out to be exceptionally colossal in size and complex in nature. These databases hold extensive and heterogeneous information, with huge number of relations and qualities. So it is exceptionally hard to outline an arrangement of static inquiry structures to answer different specially appointed database inquirieson these cutting edge databases. Along these lines there is need of such framework which create Query Forms powerfully as indicated by the clients need at run time. The proposed framework Dynamic Query Form i.e.DQF framework going to give an answer by the inquiry interface in extensive and complex databases. In proposed framework, the center idea is to catch client intrigues all through client associations and to adjust the inquiry sort iteratively. Each cycle comprises of 2 sorts of client collaborations: Query Form Enrichment and Query Execution. In Query Form Enrichment DQF would prescribe a positioned rundown of question structure part to client so he/she can choose sought structure segments into current inquiry structure. In Query Execution client fills current inquiry shape and submit question, DQF going to show result and take input from client on gave question results. A client would have office to fill the inquiry frame and submit questions to see the inquiry result at every cycle. So that a question structure could be progressively refined till the client fulfills with the inquiry results