Impact of Uncorrected Vision on Productivity-A study in an Industrial setting a Pair of Spectacles

Background: According to the World Health Organization (WHO) around one billion people worldwide in developing countries need vision correction. Uuncorrected vision is believed to be responsible for a widespread loss of labour productivity and quality, reading and literacy problems, and other problems such as road and domestic accidents.There is however, a lack of data on both the prevalence and the effects of uncorrected vision. As a result, governments and funding agencies have been hesitant to prioritise vision correction in their health and social development agenda.This acute lack of access to vision correction across the developing world is primarily due to inadequate number of eye care professionals, facilities and the high cost of providing spectacles.Objective of the study: As there are not any studies in the area of uncorrected vision and impact on productivity, this study was undertaken as a pilot study with an intention of understanding the impact of productivity among employees needing vision correction in comparison with those not needing correction but doing identical work, and to measure subsequent changes in productivity following vision correction among the former group through the supply of prescription spectacles.Method: Tthe research was undertaken among a group of 238 workers engaged in spinning and winding function at a cotton spinning and textile factory in Madurai. productivity data was collected for 30 working shifts for each employee. Tthen the eye test was done by a team comprising of Ophthalmologist and Optometrist from Aravind Eeye Hospital (WHO Collaborating Centre) and given the corrective glass to those who were prescribed the correction. after a month of gap given to get used to the glasses, again the productivity data was collected for 30 working shifts for all the samples in the first phase and analysed.Results: Out of the 238 (111 Sspinners + 127 Winders) workers undergone eyesight testing, 187 (90 + 97 Winders) workers needed vision correction which is around 80% of the total test done. Of these 187 needing vision correction, 169 (75%) were presbyopic and needed glasses for near vision correction. All those who were identified as needing vision correction were given spectacles. In terms of productivity measurement, though there were problems in tracking the data each employee wise due to various reasons as the industry was undergoing a transition at that point of time. With the best available data, the spinners showed an average improvement of 9.5% (with a standard error in the mean of 1.6); 44% improved their productivity by more 10% on previous output levels whilst 23% exceeded them by 20%. Tthe winders showed less change after the provision of spectacles with 23% increasing their productivity by 10% of the factory standard, demonstrating that this task made less demand on workers visual acuity. Pradhan, KB120Conclusion: A significantly higher proportion of industry workers having poor vision due to Refractive error. Tthey never try to correct this error unless the vision problem is a major hurdle in their work and social life. Tthe ignorance may be due to, not a painful problem, access to immediate services in eye care, cost of services, inconvenience in using a foreign object, cosmetic value, no realization of quality and performance attached to work.Constraints: study could have been better if these following constraints were not there Industry was undergoing a transition from Manual to Automation processes. Tthere was drive of Voluntary Retirement scheme (VRSs). If the study team could have got more time to think over the strategy and methodology.Policy Issues: Tthe sight test result showed a high percentage of uncorrected refractive error in a high profile industrial setting. Tthis could mean some percentage of loss of productivity and also a stake in quality of the product due to sight problem. gives an impression to study on subjects who are involved in products linked to productivity and quality like export products, jewellary, thread work, handicrafts, textiles, manual industrial works and also life threatening workers like driving and food products industries, where good sight means a lot. As a policy the industrial settings should include eye testing in to their regular health screening programmes as this has direct implications to the work and outcome of the industry

Unleashing the power of Virtual Reality to manage LAZY EYE-A silent public health problem: A case study from India

Amblyopia, also known as "lazy eye," is a childhood vision disorder characterized by impaired coordination between the brain and the eye, resulting in decreased vision in one eye. It is not caused by any structural abnormalities in the eye but rather by a lack of effective coordination between the eye and brain during the crucial period of visual development in early childhood.(1) Amblyopia is a significant global public health issue, with an estimated prevalence of 1-5% of the global population according to the World Health Organization (WHO). Developing countries face a higher burden of amblyopia due to limited access to early diagnosis and treatment. If left untreated, amblyopia can result in permanent vision loss and impairment, negatively impacting an individual's quality of life, educational achievements, and career prospects.(1) A 2017 study explored the prevalence and impact of amblyopia and strabismus in Indian children. The study found a prevalence rate of 1.67% for amblyopia among children aged 5-15 years, with a higher occurrence in rural areas compared to urban areas.(2)  In another study conducted by Gupta et al. found the percentage of amblyopia was 8.6% (n=31) among 5-15 years children in uttrakhand.(3) Another study conducted by Ganekal et al. revealed the prevalence of amblyopia was 1.1% (n?=?44) among 5-15 years of students.(4) The research emphasized the importance of enhanced awareness, early detection, and improved access to suitable treatment options to alleviate the burden of amblyopia in India. Furthermore, the All India Ophthalmological Society (AIOS) conducted a study in 2019 titled "AIOS Guidelines for Amblyopia Management." This study aimed to provide evidence-based guidelines for managing amblyopia in India. It highlighted the lack of awareness and limited availability of eye care services in certain regions, leading to delayed diagnosis and treatment of amblyopia. The guidelines emphasized the significance of early screening, timely intervention, and appropriate treatment approaches to prevent long-term visual impairment in children.(5

Socioeconomic Inequalities in the Prevalence of Non-Communicable Diseases among Older Adults in India

Understanding socioeconomic inequalities in non-communicable disease prevalence and preventive care usage can help design effective action plans for health equality programs among India’s aging population. Hypertension (HTN) and diabetes mellitus (DM) are frequently used as model non-communicable diseases for research and policy purposes as these two are the most prevalent NCDs in India and are the leading causes of mortality. For this investigation, data on 31,464 older persons (aged 60 years and above) who took part in the Longitudinal Ageing Survey of India (LASI: 2017–2018) were analyzed. The concentration index was used to assess socioeconomic inequality whereas relative inequalities indices were used to compare HTN, DM, and preventive care usage between the different groups of individuals based on socioeconomic status. The study reveals that wealthy older adults in India had a higher frequency of HTN and DM than the poor elderly. Significant differences in the usage of preventive care, such as blood pressure/blood glucose monitoring, were found among people with HTN or DM. Furthermore, economic position, education, type of work, and residential status were identified as important factors for monitoring inequalities in access to preventive care for HTN and DM. Disparities in non-communicable diseases can be both a cause and an effect of inequality across social strata in India

Cardiovascular Disease Outcomes Associated with Obstructive Sleep Apnea in Diabetics: A Systematic Review and Meta-Analysis

Background: There is significant pathogenic and epidemiological overlap between diabetes and obstructive sleep apnea (OSA). This systematic review aimed to ascertain the association between OSA and cardiovascular disease (CVD) in a diabetic population. Methods: The study protocol was registered with PROSPERO (CRD42023404126). On 15 July 2023, a comprehensive search of the literature was performed in PubMed, EBSCO, Scopus, ProQuest, and Web of Science, using keywords and synonyms of OSA, diabetes, and CVD, coupled with specific terms for different CVDs. Only observational studies that reported CVD events in diabetics (with and without OSA) were included. The quality of the studies included in the analysis was assessed using the Newcastle–Ottawa Scale. Results: In the primary literature search, 8795 studies were identified, of which 9 met the inclusion criteria and included 17,796 participants. Eight studies were eligible for meta-analysis, and a pooled risk ratio (RR) of 1.29 (95% CI = 0.91–1.83) was found for developing CVD in diabetics with OSA at a 95% prediction interval of 0.30–5.60. The included studies showed significant heterogeneity with an I2 value of 91%. Conclusion: These findings show the possible association between OSA and diabetes and their impact on CVDs. Identifying and managing OSA in individuals with diabetes at an early phase could potentially reduce the risk of CVDs and its related complications

Viral Loads in Skin Samples of Patients with Monkeypox Virus Infection: A Systematic Review and Meta-Analysis

Despite monkeypox (mpox) being a public health emergency, there is limited knowledge about the risk of infectivity from skin viral loads during mpox infection. Thus, the aim of this study was to estimate cutaneous viral loads among mpox patients globally. Several databases, including Cochrane, EBSCOHost, EMBASE, ProQuest, PubMed, Scopus, and Web of Science, and preprint servers were searched concerning skin mpox viral loads in confirmed mpox subjects. In this systematic review and meta-analysis, a total of 331 articles were initially screened after the removal of duplicate entries. A total of nine articles were included in the systematic review and meta-analysis for the overall estimation of viral loads (Ct) using a random-effect model. The pooled cutaneous mpox viral load (lower Ct) was 21.71 (95% CI: 20.68–22.75) with a majority of positivity rates being 100%, highlighting a higher infectivity risk from skin lesions. The current results strongly support that skin mpox viral loads may be a dominant source of rapid transmission during current multi-national outbreaks. This important finding can help in constructing useful measures in relevant health policy

A meta-analysis and mapping of global mpox infection among children and adolescents

Monkeypox (mpox) is a significant health concern affecting children and adolescents globally. This systematic review and meta-analysis aims to synthesise the available evidence on the proportion of children and adolescents affected by the mpox virus. A comprehensive search was conducted in seven electronic databases (PubMed, Scopus, Web of Science, EMBASE, ProQuest, EBSCOHost, and Cochrane) to identify the original reports on mpox cases in children and adolescents till 15 January 2023. Descriptive reports on probable or laboratory-confirmed mpox in children and adolescents (0-17 years old) were considered eligible. Studies not providing separate data for the above age group and case-control studies were excluded. The primary outcome was pooled proportion of mpox cases among children and adolescents. Proportion meta-analysis and heterogeneity between studies were determined using a restricted maximum likelihood estimator, and a random-effects model was fitted to the data. Sensitivity analysis and subgroup analysis were also conducted. A drapery plot was also provided as a complementary figure to the forest plot. The protocol was prospectively registered with PROSPERO (CRD42023392475). A total of 440 studies were identified, of which 37 were included in the review and 25 in the meta-analysis (62,701 participants with 3306 children and adolescents). The pooled proportion of children and adolescents was 0.46 (95% CI: 0.30-0.63, I$^{2}$ :100%). The proportion of children and adolescents was significantly lower (p < 0.001) in the ongoing pandemic 0.04 (95% CI: 0.00-0.32) than before 2022 0.62 (95% CI: 0.49-0.74). The meta-regression showed that the higher the study's sample size, the lower the proportion of children among the mpox cases. Both overall and subgroup heterogeneity were high. Adolescents and children below 5 years are commonly affected by the ongoing pandemic. In conclusion, the high proportion of children affected by the mpox virus highlights the need for increased research and targeted interventions to prevent and control the spread of the virus in this population

Pharmacological treatment and vaccines in monkeypox virus: a narrative review and bibliometric analysis

Mpox (earlier known as monkeypox) virus infection is a recognized public health emergency. There has been little research on the treatment options. This article reviews the specific drugs used to treat mpox virus infection and the vaccines used here. Instead of focusing on the mechanistic basis, this review narrates the practical, real-life experiences of individual patients of mpox virus disease being administered these medicines. We conducted a bibliometric analysis on the treatment of the mpox virus using data from several databases like PubMed, Scopus, and Embase. The research on this topic has grown tremendously recently but it is highly concentrated in a few countries. Cidofovir is the most studied drug. This is because it is indicated and also used off-label for several conditions. The drugs used for mpox virus infection include tecovirimat, cidofovir, brincidofovir, vaccinia immune globulin, and trifluridine. Tecovirimat is used most frequently. It is a promising option in progressive mpox disease in terms of both efficacy and safety. Brincidofovir has been associated with treatment discontinuation due to elevated hepatic enzymes. Cidofovir is also not the preferred drug, often used because of the unavailability of tecovirimat. Trifluridine is used topically as an add-on agent along with tecovirimat for ocular manifestations of mpox virus disease. No study reports individual patient data for vaccinia immune globulin. Though no vaccine is currently approved for mpox virus infection, ACAM 2000 and JYNNEOS are the vaccines being mainly considered. ACAM 2000 is capable of replicating and may cause severe adverse reactions. It is used when JYNNEOS is contraindicated. Several drugs and vaccines are under development and have been discussed alongside pragmatic aspects of mpox virus treatment and prevention. Further studies can provide more insight into the safety and efficacy of Tecovirimat in actively progressing mpox virus disease