208 research outputs found
PUK4 PHARMACOECONOMIC EVALUATION OF SOLIFENACIN IN THE TREATMENT OF OVERACTIVE BLADDER SYNDROME IN ITALY
PCV24 COST EFFECTIVENESS OF THE CARDIOVASCULAR PREVENTION WITH RAMIPRIL AND/OR STATINS IN HIGH RISK POPULATION IN ITALY
PDB5 PREVENTION WITH PICOTAMIDE AND ASPIRIN IN PATIENTS WITH TYPE 2 DIABETES MELLITUS AND PERIPHERAL ARTERIAL DISEASE:A PHARMACOECONOMIC EVALUATION
PDB24 Budget Impact Analysis of the Use of Aspart Insulin During Hospitalization of Patients with Hyperglycaemia in Italy
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Supplemental parenteral nutrition in intensive care patients: A cost saving strategy.
The Swiss supplemental parenteral nutrition (SPN) study demonstrated that optimised energy provision combining enteral nutrition (EN) and SPN reduces nosocomial infections in critically ill adults who fail to achieve targeted energy delivery with EN alone. To assess the economic impact of this strategy, we performed a cost-effectiveness analysis using data from the SPN study.
Multivariable regression analyses were performed to characterise the relationships between SPN, cumulative energy deficit, nosocomial infection, and resource consumption. The results were used as inputs for a deterministic simulation model evaluating the cost-effectiveness of SPN administered on days 4-8 in patients who fail to achieve ≥60% of targeted energy delivery with EN by day 3. Cost data were derived primarily from Swiss diagnosis-related case costs and official labour statistics.
Provision of SPN on days 4-8 was associated with a mean decrease of 2320 ± 338 kcal in cumulative energy deficit compared with EN alone (p < 0.001). Logistic regression analysis showed that each 1000 kcal decrease in cumulative energy deficit was associated with a 10% reduction in the risk of nosocomial infection (odds ratio 0.90; 95% confidence interval 0.83-0.99; p < 0.05). The incremental cost per avoided infection was -63,048 CHF, indicating that the reduction in infection was achieved at a lower cost.
Optimisation of energy provision using SPN is a cost-saving strategy in critically ill adults for whom EN is insufficient to meet energy requirements
CV3 Outcomes and Costs of Concomitant Aortic Valve Replacements Associated With a New Sutureless and Collapsed Valve in Italy, France, Germany, and the UK
PCN139 Cost-Effectiveness Analysis Of Neo-Adjuvant Pertuzumab Therapy In Women With Locally Advanced, Inflammatory, Or Early Her2-Positive Breast Cancer In Italy
PUK15 A Simulation Model of The Effects of Treatments for Secondary Hyperparathyroidism on Mortality
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