4 research outputs found

    Early diagnosis and meta-agnostic model visualization of tuberculosis based on radiography images

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    Abstract Despite being treatable and preventable, tuberculosis (TB) affected one-fourth of the world population in 2019, and it took the lives of 1.4 million people in 2019. It affected 1.2 million children around the world in the same year. As it is an infectious bacterial disease, the early diagnosis of TB prevents further transmission and increases the survival rate of the affected person. One of the standard diagnosis methods is the sputum culture test. Diagnosing and rapid sputum test results usually take one to eight weeks in 24 h. Using posterior-anterior chest radiographs (CXR) facilitates a rapid and more cost-effective early diagnosis of tuberculosis. Due to intraclass variations and interclass similarities in the images, TB prognosis from CXR is difficult. We proposed an early TB diagnosis system (tbXpert) based on deep learning methods. Deep Fused Linear Triangulation (FLT) is considered for CXR images to reconcile intraclass variation and interclass similarities. To improve the robustness of the prognosis approach, deep information must be obtained from the minimal radiation and uneven quality CXR images. The advanced FLT method accurately visualizes the infected region in the CXR without segmentation. Deep fused images are trained by the Deep learning network (DLN) with residual connections. The largest standard database, comprised of 3500 TB CXR images and 3500 normal CXR images, is utilized for training and validating the recommended model. Specificity, sensitivity, Accuracy, and AUC are estimated to determine the performance of the proposed systems. The proposed system demonstrates a maximum testing accuracy of 99.2%, a sensitivity of 98.9%, a specificity of 99.6%, a precision of 99.6%, and an AUC of 99.4%, all of which are pretty high when compared to current state-of-the-art deep learning approaches for the prognosis of tuberculosis. To lessen the radiologist’s time, effort, and reliance on the level of competence of the specialist, the suggested system named tbXpert can be deployed as a computer-aided diagnosis technique for tuberculosis

    IoT Based Health—Related Topic Recognition from Emerging Online Health Community (Med Help) Using Machine Learning Technique

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    The unprompted patient’s and inimitable physician’s experience shared on online health communities (OHCs) contain a wealth of unexploited knowledge. Med Help and eHealth are some of the online health communities offering new insights and solutions to all health issues. Diabetes mellitus (DM), thyroid disorders and tuberculosis (TB) are chronic diseases increasing rapidly every year. As part of the project described in this article comments related to the diseases from Med Help were collected. The comments contain the patient and doctor discussions in an unstructured format. The sematic vision of the internet of things (IoT) plays a vital role in organizing the collected data. We pre-processed the data using standard natural language processing techniques and extracted the essential features of the words using the chi-squared test. After preprocessing the documents, we clustered them using the K-means++ algorithm, which is a popular centroid-based unsupervised iterative machine learning algorithm. A generative probabilistic model (LDA) was used to identify the essential topic in each cluster. This type of framework will empower the patients and doctors to identify the similarity and dissimilarity about the various diseases and important keywords among the diseases in the form of symptoms, medical tests and habits

    Histones: At the Crossroads of Peptide and Protein Chemistry

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