3 research outputs found
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Essays on Consumer Behavior and Analytics
The first chapter of my dissertation is joint work with Professor Karsten Hansen. This chapter examines gender differences in grocery retail shopping. We used consumer transaction data over the length of 12 years to find that the typical female consumer is less concentrated in choice of retail outlet, product category, brand choice and is more responsive to promotions than male shoppers. The findings are confirmed in both the “raw data” and regression analysis (including other demographic factors). The second chapter is a solo-authored paper. Chapter 2 examines consumer behavior in response to manipulations of an increasingly popular price framework, called ‘drip pricing’. Our research is the first to provide insights through the manipulation (salience, magnitude, and type) of its two primary elements: the base price and surcharges. We conduct eight field experiments on a popular travel platform to document causal effects on the search and purchase process. My findings confirm the importance of the headline price as an ‘anchor’ in this framework; additionally, its removal led to higher quality tickets purchased but led to a reduced quantity of tickets sold. When surcharge information is shrouded, customers are not information seeking and did not seek price information and made purchases based on the most pertinent data. Consumers are more sensitive to changes in fees at lower prices and are responsive to variations in the type of surcharge. Additionally, customers are responsive to taxes rather than fee surcharges
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Efficacy and Safety of Stereotactic Body Radiation Therapy for Pediatric Malignancies: The LITE-SABR Systematic Review and Meta-Analysis.
PURPOSE: Limited data are currently available on clinical outcomes after stereotactic body radiation therapy (SBRT) for pediatric and adolescent and young adult (AYA) patients with cancer. We aimed to perform a systematic review and study-level meta-analysis to characterize associated local control (LC), progression-free survival (PFS), overall survival, and toxicity after SBRT. METHODS AND MATERIALS: Relevant studies were queried using a Population, Intervention, Control, Outcomes, Study Design (PICOS)/Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)/Meta-analysis of Observational Studies in Epidemiology (MOOSE) selection criteria. Primary outcomes were 1-year and 2-year LC as well as incidence of acute and late grade 3 to 5 toxicities, with secondary outcomes of 1-year overall survival and 1-year PFS. Outcome effect sizes were estimated with weighted random effects meta-analyses. Mixed-effects weighted regression models were performed to examine potential correlations between biologically effective dose (BED10), LC, and toxicity incidence. RESULTS: Across 9 published studies, we identified 142 pediatric and AYA patients with 217 lesions that were treated with SBRT. Estimated 1-year and 2-year LC rates were 83.5% (95% confidence interval, 70.9%-96.2%) and 74.0% (95% CI, 64.6%-83.4%), respectively, with an estimated acute and late grade 3 to 5 toxicity rate of 2.9% (95% CI, 0.4%-5.4%; all grade 3). The estimated 1-year OS and PFS rates were 75.4% (95% CI, 54.5%-96.3%) and 27.1% (95% CI, 17.3%-37.0%), respectively. On meta-regression, higher BED10 was correlated with improved 2-year LC with every 10 Gy10 increase in BED10 associated with a 5% improvement in 2-year LC (P = .02) in sarcoma-predominant cohorts. CONCLUSIONS: SBRT provided durable LC for pediatric and AYA patients with cancer with minimal severe toxicities. Dose escalation may result in improved LC for sarcoma-predominant cohorts without a subsequent increase in toxicity. However, further investigations with patient-level data and prospective inquiries are indicated to better define the role of SBRT based on patient and tumor-specific characteristics