Ostry zespół sercowo−nerkowy: powrót funkcji nerek po leczeniu nerkozastępczym

Utilisation of invasive treatment in the form of elective dialysis end extracorporeal ultrafiltration as a method of complementaryto pharmacotherapy was presented by the example of the patient with acute decompensated heart failure with diagnosedcardiorenal syndrome type 1. Such procedure reduced symptoms of overhydration, restored sensitivity to oral diureticsand allow to obtain a partial return of renal function, improved prognosis and quality of life of the patient

Skuteczne leczenie niewydolności serca opornej na diuretyki za pomocą ultrafiltracji otrzewnowej

We present a case of successful peritoneal ultrafiltration (pUF) treatment in a 60 year-old patient diagnosed with diuretic-resistantcongestive heart failure fulfilling the criteria for type 2 cardio-renal syndrome. Six months of pUF treatment with onedaily dialysis exchange with icodextrin as an osmotic agent resulted in better functional status (from IV to II/III NYHA class),quality of life and improvement of haemodynamic parameters measured by impedance cardiography. During the follow-up(six months), pUF was well tolerated by the patient and he did not require hospitalisation for decompensated heart failure

Nutritional assessment of omega-3 fatty acids intake in schizophrenia patients group

Introduction: Schizophrenia is a chronic mental disease which significantly affects functioning and quality of life of patients. Lifestyle, including irregular eating habits, is a factor possibly intensifying symptoms of the disease and unwanted effects of pharmacotherapy. Due to positive effect on metabolic parameters demonstrated in numerous studies and participation in structure and functioning of central nervous system, omega-3 essential unsaturated fatty acids (EFAs) are the suggested form of schizophrenia cotheraphy

Discrepancies in assessment of patients with rheumatoid arthritis and secondary Sjögren's syndrome by DAS28-ESR and DAS28-CRP

Abstract Objectives: to investigate whether a difference exists between das28 from crP and das28 from esr in patients with rheumatoid arthritis (ra) and secondary sjögren's syndrome (sss). Material and methods: One group comprised patients with RA and sSS, the control group comprised patients with ra. the inclusion criteria for the ra and sss group have been specified as follows: presence of at least one symptom of dryness, and also presence of anti-SS-A and anti-SS-B or at least focus score of one in biopsy. Results: the disease activity score 28 (das28) was assessed using both esr and crP in 60 patients with ra and sss and 59 patients with ra alone. however, concordance between these two methods was good (cohen's κ coefficient κ = 0. 60, 95% ci: 0.45-0.7

The Role of TNF-α and Anti-TNF-α Agents during Preconception, Pregnancy, and Breastfeeding

Tumor necrosis factor-alpha (TNF-α) is a multifunctional Th1 cytokine and one of the most important inflammatory cytokines. In pregnancy, TNF-α influences hormone synthesis, placental architecture, and embryonic development. It was also shown that increased levels of TNF-α are associated with pregnancy loss and preeclampsia. Increased TNF-α levels in complicated pregnancy draw attention to trophoblast biology, especially migratory activity, syncytialisation, and endocrine function. Additionally, elevated TNF-α levels may affect the maternal-fetal relationship by altering the secretory profile of placental immunomodulatory factors, which in turn affects maternal immune cells. There is growing evidence that metabolic/pro-inflammatory cytokines can program early placental functions and growth in the first trimester of pregnancy. Furthermore, early pregnancy placenta has a direct impact on fetal development and maternal immune system diseases that release inflammatory (e.g., TNF-α) and immunomodulatory factors, such as chronic inflammatory rheumatic, gastroenterological, or dermatological diseases, and may result in an abnormal release of cytokines and chemokines in syncytiotrophoblasts. Pregnancy poses a challenge in the treatment of chronic disease in patients who plan to have children. The activity of the disease, the impact of pregnancy on the course of the disease, and the safety of pharmacotherapy, including anti-rheumatic agents, in pregnancy should be considered

The role of oxytocin in the pathogenesis and treatment of schizophrenia

Introduction: Until recently, oxytocin was mainly associated with the pathophysiology of childbirth and sexual functions, but lately this hormone has become the object of interest to psychiatry and psychology due to the significant influence of oxytocin on human behavior in the field of social and emotional functioning. Current scientific research focuses on the participation of oxytocin in the pathogenesis and therapy of mental disorders