Endothelotropic activity of 4-hydroxy-3,5-di-tret-butylcinnamic acid in the conditions of experimental cerebral ischemia

The aim of the study was to evaluate the endothelioprotective activity of 4-hydroxy-3,5-di-tret-butylcinnamic acid in conditions of experimental cerebral ischemia. The brain ischemia was reproduced by the method of irreversible right-sided thermocoagulation of the middle cerebral artery. As comparative drugs, mexidol (30 mg/kg) and sulodexide (30 U/kg) were use

Influence of scattering processes on electron quantum states in nanowires

In the framework of quantum perturbation theory the self-consistent method of calculation of electron scattering rates in nanowires with the one-dimensional electron gas in the quantum limit is worked out. The developed method allows both the collisional broadening and the quantum correlations between scattering events to be taken into account. It is an alternativeper seto the Fock approximation for the self-energy approach based on Green’s function formalism. However this approach is free of mathematical difficulties typical to the Fock approximation. Moreover, the developed method is simpler than the Fock approximation from the computational point of view. Using the approximation of stable one-particle quantum states it is proved that the electron scattering processes determine the dependence of electron energy versus its wave vector

X-ray Spectral Signatures of the Photon Bubble Model for Ultraluminous X-ray Sources

The nature of ultraluminous X-ray sources in nearby galaxies is one of the major open questions in modern X-ray astrophysics. One possible explanation for these objects is an inhomogeneous, radiation dominated accretion disk around a $\sim 10 M_{\odot}$ black hole -- the so-called ``photon bubble'' model. While previous studies of this model have focused primarily on its radiation-hydrodynamics aspects, in this paper, we provide an analysis of its X-ray spectral (continuum and possible edge and line) characteristics. Compton reflection between high and low density regions in the disk may provide the key to distinguishing this model from others, such as accretion onto an intermediate mass black hole. We couple a Monte Carlo/Fokker-Planck radiation transport code with the XSTAR code for reflection to simulate the photon spectra produced in a photon bubble model for ULXs. We find that reflection components tend to be very weak and in most cases not observable, and make predictions for the shape of the high-energy Comptonizing spectra. In many cases the Comptonization dominates the spectra even down to $\sim$ a few keV. In one simulation, a \sim 9 \kev feature was found, which may be considered a signature of photon bubbles in ULXs; furthermore, we make predictions of high energy power-laws which may be observed by future instruments.Comment: Accepted for publication in the Astrophysical Journa

Evolution of the Low-Energy Photon Spectra in Gamma-Ray Bursts

We report evidence that the asymptotic low-energy power law slope alpha (below the spectral break) of BATSE gamma-ray burst photon spectra evolves with time rather than remaining constant. We find a high degree of positive correlation exists between the time-resolved spectral break energy E_pk and alpha. In samples of 18 "hard-to-soft" and 12 "tracking" pulses, evolution of alpha was found to correlate with that of the spectral break energy E_pk at the 99.7% and 98% confidence levels respectively. We also find that in the flux rise phase of "hard-to-soft" pulses, the mean value of alpha is often positive and in some bursts the maximum value of alpha is consistent with a value > +1. BATSE burst 3B 910927, for example, has a alpha_max equal to 1.6 +/- 0.3. These findings challenge GRB spectral models in which alpha must be negative of remain constant.Comment: 12 pages (including 6 figures), accepted to Ap

Low frequency radio and X-ray properties of core-collapse supernovae

Radio and X-ray studies of young supernovae probe the interaction between the supernova shock waves and the surrounding medium and give clues to the nature and past of the progenitor star. Here we discuss the early emission from type Ic SN 2002ap and argue that repeated Compton boosting of optical photons by hot electrons presents the most natural explanation of the prompt X-ray emission. We describe the radio spectrum of another type Ic SN 2003dh (GRB030329) obtained with combined GMRT and VLA data. We report on the low frequency radio monitoring of SN 1995N and our objectives of distinguishing between competing models of X-ray emission from this SN and the nature of its progenitor by X-ray spectroscopy. Radio studies on SN 2001gd, SN 2001ig and SN 2002hh are mentioned.Comment: 5 pages, 4 figures. Uses svmult.cls. To appear in proceedings of IAU Colloquium 192 "Supernovae (10 years of SN 1993J)", April 2003, Valencia, Spain, eds. J. M. Marcaide and K. W. Weile

Compton Scattering by Static and Moving Media I. The Transfer Equation and Its Moments

Compton scattering of photons by nonrelativistic particles is thought to play an important role in forming the radiation spectrum of many astrophysical systems. Here we derive the time-dependent photon kinetic equation that describes spontaneous and induced Compton scattering as well as absorption and emission by static and moving media, the corresponding radiative transfer equation, and their zeroth and first moments, in both the system frame and in the frame comoving with the medium. We show that it is necessary to use the correct relativistic differential scattering cross section in order to obtain a photon kinetic equation that is correct to first order in epsilon/m_e, T_e/m_e, and V, where epsilon is the photon energy, T_e and m_e are the electron temperature and rest mass, and V is the electron bulk velocity in units of the speed of light. We also demonstrate that the terms in the radiative transfer equation that are second-order in V usually should be retained, because if the radiation energy density is sufficiently large compared to the radiation flux, the effects of bulk Comptonization described by the terms that are second-order in V are at least as important as the effects described by the terms that are first-order in V, even when V is small. Our equations are valid for systems of arbitrary optical depth and can therefore be used in both the free-streaming and the diffusion regimes. We demonstrate that Comptonization by the electron bulk motion occurs whether or not the radiation field is isotropic or the bulk flow converges and that it is more important than thermal Comptonization if V^2 > 3 T_e/m_e.Comment: 31 pages, accepted for publication in The Astrophysical Journa

Effect of surface modification of 5KHV2S steel on the mechanism and intensity of contact wear

The paper presents the experimental study of the contact wear of 5KHV2S steel after surface modification. It is shown that without hardening of the surface layer, 5KHV2S steel is capable of satisfactory operation when a pulsating contact stress of 970 MPa is applied. The most qualitative type of surface modification is the hardening of the surface layer by nitrocementation carried out before quenching and tempering. The proposed technology of volumetric- surface hardening, including forging in a new forging tool, chemical-thermal treatment, quenching and lowtemperature tempering, provided the possibility of increasing the pulsating contact stress to 1 100 MPa, and the operation period during the first 13 000 loading cycles gives wear of the working surface no more than 0,1 mm

Compton Scattering in Static and Moving Media. II. System-Frame Solutions for Spherically Symmetric Flows

I study the formation of Comptonization spectra in spherically symmetric, fast moving media in a flat spacetime. I analyze the mathematical character of the moments of the transfer equation in the system-frame and describe a numerical method that provides fast solutions of the time-independent radiative transfer problem that are accurate in both the diffusion and free-streaming regimes. I show that even if the flows are mildly relativistic (V~0.1, where V is the electron bulk velocity in units of the speed of light), terms that are second-order in V alter the emerging spectrum both quantitatively and qualitatively. In particular, terms that are second-order in V produce power-law spectral tails, which are the dominant feature at high energies, and therefore cannot be neglected. I further show that photons from a static source are upscattered by the bulk motion of the medium even if the velocity field does not converge. Finally, I discuss these results in the context of radial accretion onto and outflows from compact objects.Comment: 28 pages, 9 figures; minor changes, to appear in the Astrophysical Journa