Thermocouple installation

A thermocouple assembly which includes a plug having a pair of small diameter holes near one end thereof which are spaced a small distance apart to leave a thin quantity of plug material between the holes is presented. There are a pair of thermocouple wires extending through the different holes and with the outer ends of the wires joined to the thin quantity of plug material which lies between the holes to form a thermocouple junction

Development and application of computer software techniques to human factors task data handling problems Final report, 21 Jun. 1965 - 21 Jun. 1966

Computer software techniques applied to human factors task data handling problem

Reviewing media literacy intervention studies for validity

This study is an examination of validity in published articles that have provided tests of the effectiveness of media literacy interventions. We identified 88 published tests of media literacy interventions then analyzed their content using five coding variables that indicated the degree to which authors of those studies established basic validity. We first conducted a meaning analysis to identify the definitions that authors of those studies presented for media literacy. Then we used those definitions to determine the extent to which those authors provided a complete (content validity) and accurate (face validity) operationalization in the design of their measures

The role of freestream turbulence scale in subsonic flow separation

The ojective of this work is the clarification of the role of freestream turbulence scale in determining the location of boundary layer separation. An airfoil in subsonic wind tunnel flow is the specific case studied. Hot-film and hot-wire anemometry, liquid-film visualization and pressure measurements are the principal diagnostic techniques in use. The Vanderbilt University subsonic wind tunnel is the flow facility being used

The role of freestream turbulence scale in subsonic flow separation

The clarification of the role of freestream turbulence scale in determining the location of boundary layer separation is discussed. Modifications to the test facility were completed. Wind tunnel flow characteristics, including turbulence parameters, were determined with two turbulence generating grids, as well as no grid. These results are summarized. Initial results on the role of scale on turbulent boundary layer separation on the upper surface of an airfoil model are also discussed

Steroid sulfatase:a pivotal player in estrogen synthesis and metabolism

International audienceSteroid sulfatase plays a pivotal role in regulating the formation of biologically active steroids from inactive steroid sulfates. It is responsible for the hydrolysis of estrone sulfate and dehydroepiandrosterone sulfate to estrone and dehydroepiandrosterone, respectively, both of which can be subsequently reduced to steroids with estrogenic properties (i.e. estradiol and androstenediol) that can stimulate the growth of tumors in hormone-responsive tissues of the breast, endometrium and prostate. Hence, the action of steroid sulfatase is implicated in physiological processes and pathological conditions. It has been five years since our group last reviewed the important role of this enzyme in steroid synthesis and the progress made in the development of potent inhibitors of this important enzyme target. This timely review therefore concentrates on recent advances in steroid sulfatase research, and summarises the findings of clinical trials with Irosustat (BN83495), the only steroid sulfatase inhibitor that is being trialed in postmenopausal women with breast or endometrial cancer

Solar sail capture trajectories at Mercury

Mercury is an ideal environment for future planetary exploration by solar sail since it has proved difficult to reach with conventional propulsion and hence remains largely unexplored. In addition, its proximity to the Sun provides a solar sail acceleration of order ten times the sail characteristic acceleration at 1 AU. Conventional capture techniques are shown to be unsuitable for solar sails and a new method is presented. It is shown that capture is bound by upper and lower limits on the orbital elements of the approach orbit and that failure to be within limits results in a catastrophic collision with the planet. These limits are presented for a range of capture inclinations and sail characteristic accelerations. It is found that sail hyperbolic excess velocity is a critical parameter during capture at Mercury, with only a narrow allowed band in order to avoid collision with the planet. The new capture methodis demonstrated for a Mercury sample return mission

Using AI/expert system technology to automate planning and replanning for the HST servicing missions

This paper describes a knowledge-based system that has been developed to automate planning and scheduling for the Hubble Space Telescope (HST) Servicing Missions. This new system is the Servicing Mission Planning and Replanning Tool (SM/PART). SM/PART has been delivered to the HST Flight Operations Team (FOT) at Goddard Space Flight Center (GSFC) where it is being used to build integrated time lines and command plans to control the activities of the HST, Shuttle, Crew and ground systems for the next HST Servicing Mission. SM/PART reuses and extends AI/expert system technology from Interactive Experimenter Planning System (IEPS) systems to build or rebuild time lines and command plans more rapidly than was possible for previous missions where they were built manually. This capability provides an important safety factor for the HST, Shuttle and Crew in case unexpected events occur during the mission