The Hollybank Challenges: AT for People with Profound Disabilities

The use of Assistive Technology with people with profound and multiple disabilities is a specialised subfield. Drawing on its authors' experiences and observations at a UK charitable foundation that offers specialised educational, residential and therapeutic facilities, this paper describes the distinct challenges that present themselves when applying AT to address the needs of this often-overlooked sector of the community. It is hoped that this will help raise awareness and contribute to improving the overall quality of AT provision in this area

Thermal-radiation-induced nonequilibrium carriers in an intrinsic graphene

We examine an intrinsic graphene connected to the phonon thermostat at temperature T under irradiation of thermal photons with temperature T_r, other than T. The distribution of nonequilibrium electron-hole pairs was obtained for the cases of low and high concentration of carriers. For the case when the interparticle scattering is unessential, the distribution function is determined by the interplay of intraband relaxation of energy due to acoustic phonons and interband radiative transitions caused by the thermal radiation. When the Coulomb scattering dominates, then the quasi-equilibrium distribution with effective temperature and non-equilibrium concentration, determined through balance equations, is realized. Due to the effect of thermal radiation with temperature $T_r\neq T$ concentration and conductivity of carriers in graphene modify essentially. It is demonstrated, that at $T_r>T$ the negative interband absorption, caused by the inversion of carriers distribution, can occur, i.e. graphene can be unstable under thermal irradiation.Comment: 5 pages, 4 figure

Radiation calculations for the ATLAS detector and experimental hall

This paper describes the calculations performed to characterise the radiation field in the ATLAS detector at the LHC and to design the shielding of the detector and experimental areas. After a short description of the ATLAS detector, the simulations made with the MC code FLUKA are described in some detail. The radiation fields calculated in the inner cavity, in the calorimeters, in the experimental cavern, in the shafts and in an external skyshine region are presented

Coherent Optimal Control of Multiphoton Molecular Excitation

We give a framework for molecular multiphoton excitation process induced by an optimally designed electric field. The molecule is initially prepared in a coherent superposition state of two of its eigenfunctions. The relative phase of the two superposed eigenfunctions has been shown to control the optimally designed electric field which triggers the multiphoton excitation in the molecule. This brings forth flexibility in desiging the optimal field in the laboratory by suitably tuning the molecular phase and hence by choosing the most favorable interfering routes that the system follows to reach the target. We follow the quantum fluid dynamical formulation for desiging the electric field with application to HBr molecule.Comment: 5 figure

Transport of Fungal Symbionts by Mountain Pine Beetles

The perpetuation of symbiotic associations between bark beetles (Coleoptera: Curculionidae: Scolytinae) and ophiostomatoid fungi requires the consistent transport of fungi by successive beetle generations to new host trees. We used scanning electron microscopy and culture methods to investigate fungal transport by the mountain pine beetle (MPB), Dendroctonus ponderosae Hopkins. MPB transports its two main fungal associates, Grosmannia clavigera (Robinson-Jeffrey and Davidson) Zipfel, de Beer and Wingfield and Ophiostoma montium (Rumbold) von Arx, in sac-like mycangia on the maxillary cardines as well as on the exoskeleton. Although spores of both species of fungi were observed on MPB exoskeletons, often in pits, O. montium spores were generally more abundant than G. clavigera spores. However, a general scarcity of spores of either species on MPB exoskeletons compared with numbers on scolytines that lack sac-like mycangia indicates that fungal transport exteriorly on MPBs is incidental rather than adaptive. Conidia were the dominant spore type transported regardless of location or species; however, our results suggest that once acquired in mycangia, conidia may reproduce in a yeast-like form and even produce hypha-like strands and compact conidiophore-like structures. Fungi that propagate in mycangia may provide beetles with a continual source of inocula during the extended egg-laying period

Imaging faint brown dwarf companions close to bright stars with a small, well-corrected telescope aperture

We have used our 1.6 m diameter off-axis well-corrected sub-aperture (WCS) on the Palomar Hale telescope in concert with a small inner-working-angle (IWA) phase-mask coronagraph to image the immediate environs of a small number of nearby stars. Test cases included three stars (HD 130948, HD 49197 and HR7672) with known brown dwarf companions at small separations, all of which were detected. We also present the initial detection of a new object close to the nearby young G0V star HD171488. Follow up observations are needed to determine if this object is a bona fide companion, but its flux is consistent with the flux of a young brown dwarf or low mass M star at the same distance as the primary. Interestingly, at small angles our WCS coronagraph demonstrates a limiting detectable contrast comparable to that of extant Lyot coronagraphs on much larger telescopes corrected with current-generation AO systems. This suggests that small apertures corrected to extreme adaptive optics (ExAO) levels can be used to carry out initial surveys for close brown dwarf and stellar companions, leaving followup observations for larger telescopes.Comment: accepted for publication in the Astrophysical Journa

Indium diffusion in the chemical potential gradient at an In0.53Ga0.47As/In0.52Al0.48As interface

We have measured the distribution of group III metals at In0.53Ga0.47As/In0.52Al0.48As interfaces before and after annealing at 1085 K. We find little evidence for Al interdiffusion, but the Ga concentration profiles show some broadening on annealing. Also, the originally nearly constant In profiles develop strong modulations with near discontinuities at the original interfaces. This phenomenon is explained and modeled in terms of In diffusion in the chemical potential gradient established by the disparity of the Al and Ga mobilities and the requirement of III‐V stoichiometry in the alloys.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/70043/2/APPLAB-52-24-2055-1.pd

Impurity‐induced layer disordering of In0.53Ga0.47As/In0.52Al0.48As heterostructures

Impurity‐induced layer disordering of In0.53 Ga0.47 As/In0.52 Al0.48 As heterostructures grown by molecular beam epitaxy has been observed by Auger electron spectroscopy depth profiling. We find that Si+ ion implantation to concentrations greater than 2×1019 atoms cm−3 enhances the intermixing of Ga and Al in these heterostructures at an annealing temperature of 1075 K. However, the relatively high temperature which is required to activate the interdiffusion of Ga and Al in the region of high Si concentration is sufficient to induce In diffusion in regions of lower Si concentration. Zinc diffusion is found to completely intermix the Ga and Al in the heterolayers at temperatures as low as 825 K, which is below the temperature at which significant In diffusion occurs in undoped regions.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/70858/2/APPLAB-53-23-2302-1.pd

Effect of Stress on Viral–Bacterial Synergy in Bovine Respiratory Disease: Novel Mechanisms to Regulate Inflammation

The severity of bovine respiratory infections has been linked to a variety offactors, including environmental and nutritional changes, transportation, and socialreorganization of weaned calves. Fatal respiratory infections, however, usually occurwhen a primary viral infection compromises host defences and enhances the severityof a secondary bacterial infection. This viral–bacterial synergy can occur by a numberof different mechanisms and disease challenge models have been developed to analysehost responses during these respiratory infections. A primary bovine herpesvirus-1(BHV-1) respiratory infection followed by a secondary challenge with Mannheimia haemolyticaresults in fatal bovine respiratory disease (BRD) and host responses to these two pathogens have been studied extensively. We used this disease model todemonstrate that stress significantly altered the viral–bacterial synergy resulting infatal BRD. Functional genomic analysis revealed that BHV-1 infection enhanced toll-likereceptors (TLR) expression and increased pro-inflammatory responses whichcontribute to the severity of a Mannheimia haemolytica infection. TLRs play a criticalrole in detecting bacterial infections and inducing pro-inflammatory responses. It isdifficult to understand, however, how stress-induced corticosteroids could enhancethis form of viral–bacterial synergy. Nuclear translocation of the glucocorticoidreceptor activates cell signalling pathways which inhibit both TLR signallingand pro-inflammatory responses. The apparent conundrum between stress-inducedcorticosteroids and enhanced BRD susceptibility is discussed in terms of present data and previous investigations of stress and respiratory disease