Microwave Spectroscopy

Contains reports on five research projects

Microwave Spectroscopy

Contains reports on four research projects

Soliton Dynamics in Computational Anatomy

Computational anatomy (CA) has introduced the idea of anatomical structures being transformed by geodesic deformations on groups of diffeomorphisms. Among these geometric structures, landmarks and image outlines in CA are shown to be singular solutions of a partial differential equation that is called the geodesic EPDiff equation. A recently discovered momentum map for singular solutions of EPDiff yields their canonical Hamiltonian formulation, which in turn provides a complete parameterization of the landmarks by their canonical positions and momenta. The momentum map provides an isomorphism between landmarks (and outlines) for images and singular soliton solutions of the EPDiff equation. This isomorphism suggests a new dynamical paradigm for CA, as well as new data representation.Comment: published in NeuroImag

Os desafios da Criança com dificuldade de acesso Venoso e o uso de emicizumabe

A hemofilia seja ela A ou B é classificada como uma doença rara, geralmente é hereditária, ligada ao cromossomo X e por isso sua prevalência se manifesta em sua maioria no sexo masculino. É uma doença hemorrágica, ou seja, que impede a coagulação do sangue de forma efetiva e sua gravidade é classificada através da quantificação do percentual de fator ativo; dependendo da gravidade da doença o paciente hemofílico pode apresentar sangramento tanto pós trauma como espontâneos em qualquer lugar do corpo, sendo o mais comum o sangramento intra-articular e muscular. Essa propensão a sangramentos afeta muito a qualidade de vida do paciente juntamente com sua família. A cada dia vem surgindo mais estudos para introdução de novas terapias de tratamento para que o paciente tenha uma qualidade e expectativa de vida maior e melhor, sem tantos percalços na convivência com a doença

Symposium Egon Eiermann

SYMPOSIUM EGON EIERMANN Symposium Egon Eiermann (-) Einband (-) Inhaltsverzeichnis (-) "Treffen mit Egon Eiermann" (1) "Egon Eiermann - Architekt, Lehrer und Leitbild" (1) "Persönliches und Aufgelesenes - Egon Eiermann und seine Zeit" ([1]) "Egon Eiermann und seine Architektur in den dreißiger Jahren" (1) Farbinformation (-) Einband (-

The ongoing pursuit of neuroprotective therapies in Parkinson disease

Many agents developed for neuroprotective treatment of Parkinson disease (PD) have shown great promise in the laboratory, but none have translated to positive results in patients with PD. Potential neuroprotective drugs, such as ubiquinone, creatine and PYM50028, have failed to show any clinical benefits in recent high-profile clinical trials. This 'failure to translate' is likely to be related primarily to our incomplete understanding of the pathogenic mechanisms underlying PD, and excessive reliance on data from toxin-based animal models to judge which agents should be selected for clinical trials. Restricted resources inevitably mean that difficult compromises must be made in terms of trial design, and reliable estimation of efficacy is further hampered by the absence of validated biomarkers of disease progression. Drug development in PD dementia has been mostly unsuccessful; however, emerging biochemical, genetic and pathological evidence suggests a link between tau and amyloid-β deposition and cognitive decline in PD, potentially opening up new possibilities for therapeutic intervention. This Review discusses the most important 'druggable' disease mechanisms in PD, as well as the most-promising drugs that are being evaluated for their potential efficiency in treatment of motor and cognitive impairments in PD

Microwave Spectroscopy

Contains reports on four research projects