Review: The Journal of Dramaturgy, volume 22, issue 1, part 1

Contents include: Editors\u27 Notes; The 2011 Lessing Award D.D. Kugler, You Might Be Pretty Good at This An Introduction by Geoff Proehl; The 2011 Lessing Award D.D. Kugler, An Introduction by Vanessa Porteous; he 2011 Lessing Award D.D. Kugler,Welcoming Failure, Acknowledging Subjectivity, Acceptance Speech; 2011 Elliott Hayes Award Introduction; 2011 Elliott Hayes Award Acceptance Speech; Journey to China. Issue editors: D.J. Hopkins, Sydney Cheek O\u27Donnellhttps://soundideas.pugetsound.edu/lmdareview/1043/thumbnail.jp

Variants associated withHHIP expression have sex-differential effects on lung function

Background: Lung function is highly heritable and differs between the sexes throughout life. However, little is known about sex-differential genetic effects on lung function. We aimed to conduct the first genome-wide genotype-by-sex interaction study on lung function to identify genetic effects that differ between males and females. Methods: We tested for interactions between 7,745,864 variants and sex on spirometry-based measures of lung function in UK Biobank (N=303,612), and sought replication in 75,696 independent individuals from the SpiroMeta consortium. Results: Five independent single-nucleotide polymorphisms (SNPs) showed genome-wide significant (P</p