Behaviour of the additive finite locus model

International audienc

A tunable common mode inductor with an auxiliary winding network

Paper 1593Track no. 5 - Devices and ComponentsIn conventional switching converter, the parasitic capacitance between switching circuit and ground introduces common mode (CM) noise problem. A CM inductor is inserted in the power feeding paths to produce a high impedance to attenuate the CM noise. However, this parasitic capacitance and the CM inductor create low-frequency resonance near the switching frequency and its harmonics. Thus, the filtering performance is diminished. Increasing the CM inductance to shift the resonant frequency to low-frequency range is one of the methods to tackle this problem. However, this approach leads to increase the power losses (both core and winding losses) of the CM inductor reducing the efficiency of the converter. In this paper, a tunable CM inductor with a small-space auxiliary winding is proposed. The auxiliary winding can be connected to a passive network to alter the frequency response of the CM inductor without affecting the original inductance. As a result, the influence of the low-frequency resonance can be mitigated. A proof-of-concept protytpe is constructed and its performance is experimentally measured. Results show that the proposed tunable CM inductor operates as theoretically anticipated. © IEEE.published_or_final_versio

Elimination of hysteresis effect in superparamagnetic nanoparticle detection by GMR sensors for biosensing

The biosensing methods utilizing superparamagnetic nanoparticles as bio-tags and giant magneto-resistive (GMR) or tunneling magnetoresistive (TMR) sensors as signal detectors have attracted increasing interests in early disease diagnosis as well as in molecular biology research area. [1] To achieve the signal of targets, one commonly used method is to compare the sensor hysteresis loops before and after the introducing of superparamagnetic nanoparticles onto sensor surface, and the sensor response variation has been regarded as an indicator of target analyte's amount. [2, 3] However, the hysteresis effect existing in ferromagnetic material may bring an error in the sensor output reading, which can be problematic in the superparamagnetic nanoparticle signal detection. Since the hysteresis behavior exists in all magnetoresistive sensors made of ferromagnetic material, it is necessary to investigate its effect on superparamagnetic nanoparticle detection and eliminate its negative influences. © 2015 IEEE.postprin

Detection of multiple quantitative trait loci and their pleiotropic effects in outbred pig populations

<p>Abstract</p> <p>Background</p> <p>Simultaneous detection of multiple QTLs (quantitative trait loci) may allow more accurate estimation of genetic effects. We have analyzed outbred commercial pig populations with different single and multiple models to clarify their genetic properties and in addition, we have investigated pleiotropy among growth and obesity traits based on allelic correlation within a gamete.</p> <p>Methods</p> <p>Three closed populations, (A) 427 individuals from a Yorkshire and Large White synthetic breed, (B) 547 Large White individuals and (C) 531 Large White individuals, were analyzed using a variance component method with one-QTL and two-QTL models. Six markers on chromosome 4 and five to seven markers on chromosome 7 were used.</p> <p>Results</p> <p>Population A displayed a high test statistic for the fat trait when applying the two-QTL model with two positions on two chromosomes. The estimated heritabilities for polygenic effects and for the first and second QTL were 19%, 17% and 21%, respectively. The high correlation of the estimated allelic effect on the same gamete and QTL test statistics suggested that the two separate QTL which were detected on different chromosomes both have pleiotropic effects on the two fat traits. Analysis of population B using the one-QTL model for three fat traits found a similar peak position on chromosome 7. Allelic effects of three fat traits from the same gamete were highly correlated suggesting the presence of a pleiotropic QTL. In population C, three growth traits also displayed similar peak positions on chromosome 7 and allelic effects from the same gamete were correlated.</p> <p>Conclusion</p> <p>Detection of the second QTL in a model reduced the polygenic heritability and should improve accuracy of estimated heritabilities for both QTLs.</p

Modeling Spatial Relations of Human Body Parts for Indexing and Retrieving Close Character Interactions

Retrieving pre-captured human motion for analyzing and synthesizing virtual character movement have been widely used in Virtual Reality (VR) and interactive computer graphics applications. In this paper, we propose a new human pose representation, called Spatial Relations of Human Body Parts (SRBP), to represent spatial relations between body parts of the subject(s), which intuitively describes how much the body parts are interacting with each other. Since SRBP is computed from the local structure (i.e. multiple body parts in proximity) of the pose instead of the information from individual or pairwise joints as in previous approaches, the new representation is robust to minor variations of individual joint location. Experimental results show that SRBP outperforms the existing skeleton-based motion retrieval and classification approaches on benchmark databases

Community-acquired pneumonia in children: cell-free plasma sequencing for diagnosis and management.

Community-acquired pneumonia (CAP) is a common cause of pediatric hospital admission. Empiric antibiotic therapy for hospitalized children with serious CAP now targets the most likely pathogen(s), including those that may demonstrate significant antibiotic resistance. Cell-free plasma next-generation sequencing (CFPNGS) was first made available for Pediatric Infectious Diseases physicians in June 1, 2017, to supplement standard-of-care diagnostic techniques. A retrospective chart review was performed for children hospitalized with CAP between June 1, 2017, and January 22, 2018, to evaluate the impact of CFPNGS. We identified 15 hospitalized children with CAP without other underlying medical conditions for whom CFPNGS was performed. CFPNGS identified a pathogen in 13 of 15 (86%) children compared with 47% for those using standard culture and PCR-based methods alone. Changes in antibiotic management were made in 7 of 15 (47%) of children as a result of CFPNGS

How easy can the barley brie : drinking culture and accounting failure at the end of the nineteenth century in Britain

Purpose &ndash; This paper seeks to extend the development of the historical accounting research agenda further into the area of popular culture. The work examines the discourses that surrounded the drinking of alcohol in nineteenth century Britain and explores how an accounting failure disrupted the tension between the two established competing discourses, leading to a significant impact on UK drinking culture at the end of the nineteenth century. Design/methodology/approach &ndash; The paper employs both primary and secondary sources. Secondary sources are used to develop the main themes of the discourses deployed by the temperance societies and the whisky companies. Primary sources derived from the contemporary press are employed, as necessary, in support. Findings &ndash; The paper demonstrates that accounting, although it may not be central to a discourse or other social structure, can still have a profound impact upon cultural practices. The potential for research into culture and accounting should not therefore be dismissed if no immediate or concrete relationship between culture and accounting can be determined. Further support is provided for studies that seek to expand the accounting research agenda into new territories. Originality/value &ndash; The study of popular culture is relatively novel in accounting research. This paper seeks to add to this research by exploring an area of cultural activity that has hitherto been neglected by researchers, i.e. by exploring how an accounting incident impacted upon the historical consumption of Scotch whisky in the UK.<br /