Parameters used for benefit-cost analysis of intervention strategies to control brucellosis in bovine populations, India (1 US $ = Rs. 60/-).

<p>Parameters used for benefit-cost analysis of intervention strategies to control brucellosis in bovine populations, India (1 US $ = Rs. 60/-).</p

Net present value (NPV) and benefit-cost ratio (BCR) of a brucellosis intervention program in cattle (first 20 years) in India.

<p>Scenario 1 –Vaccination of replacements; Scenario 2 –Vaccination for all at once followed by vaccination of replacements; Scenario 3 –Vaccination of replacements for the first 10 years followed by the test and cull for remaining 10 years.</p

Cost-benefit analysis of intervention policies for prevention and control of brucellosis in India

<div><p>Background</p><p>Brucellosis is endemic in the bovine population in India and causes a loss of US$3·4 billion to the livestock industry besides having a significant human health impact.</p><p>Methods</p><p>We developed a stochastic simulation model to estimate the impact of three alternative vaccination strategies on the prevalence of <i>Brucella</i> infection in the bovine populations in India for the next two decades: (a) annual mass vaccination only for the replacement calves and (b) vaccination of both the adult and young population at the beginning of the program followed by an annual vaccination of the replacement calves and, (c) annual mass vaccination of replacements for a decade followed by a decade of a test and slaughter strategy.</p><p>Findings</p><p>For all interventions, our results indicate that the prevalence of <i>Brucella</i> infection will drop below 2$ 4·16 billion for intervention (a), US $8·31 billion for intervention (b) and, US$ 4·26 for intervention (c). For buffalo, the corresponding NPVs were US $8·77 billion, US$ 13·42 and, US $ 7·66, respectively. The benefit cost ratio (BCR) for the first, second and the third intervention for cattle were 7·98, 10·62 and, 3·16, respectively. Corresponding BCR estimates for buffalo were 17·81, 21·27 and, 3·79, respectively.</p><p>Conclusion</p><p>These results suggest that all interventions will be cost-effective with the intervention (b), i.e. the vaccination of replacements with mass vaccination at the beginning of the program, being the most cost-effective choice. Further, sensitivity analysis revealed that all interventions will be cost-effective even at the 50% of the current prevalence estimates. The results advocate for the implementation of a disease control program for brucellosis in India.</p></div

Net present value (NPV) and benefit-cost ratio (BCR) of a brucellosis intervention program in buffalo (first 20 years) in India.

<p>Scenario 1 –Vaccination of replacements; Scenario 2 –Vaccination for all at once followed by vaccination of replacements; Scenario 3 –Vaccination of replacements for the first 10 years followed by the test and cull for remaining 10 years.</p

Changes in prevalence of brucellosis in buffaloes after the implementation of intervention programmes.

<p>Changes in prevalence of brucellosis in buffaloes after the implementation of intervention programmes.</p