Колориметрические сенсоры на гепарин с красителями толуидиновый синий и малахитовый зеленый

Мониторинг гепарина в крови используется для контроля дозировки препаратов и для оценки достаточности антикоагулянтной терапии. При курсовом приёме препаратов, содержащих гепарин, сопряженных с риском кровотечения и опасностью передозировки рекомендуется проводить лабораторный контроль терапии при слабой и умеренной почечной недостаточности , при пониженной массе тела или ожирении, при кровотечениях неясного генеза. Рассмотрена количественная сорбция различных форм толуидинового синего и малахитового зеленого, сорбированных на полиметакрилатной матрице в качестве чувствительного элемента при определении концентрации гепарина в растворах. Чувствительный полимерный элемент использовали для определения гепарина в растворах с концентрациями 50-210 мг/л. Показано, что коэффициенты чувствительности сорбционного фотометрического определения красителя пропорциональны значениям их молярных коэффициентов поглощения в водных растворах. Пределы обнаружения могут быть снижены на порядок при увеличении объема раствора на стадии сорбции и, соответственно, увеличения объема чувствительного элемента. При концентрациях свыше 10-5 моль/л возможно визуальное полуколичественное детектирование гепарина в растворе по снижению и исчезновению окраски красителя в полимерной матрице

Radio broadcasting experience and development prospects (European scientific dialogue)

The paper presents an analysis of various opinions concerning radio-industry development issues, given new IT processes implemented in mass media. The authors study the technological evolution of radio broadcasting in terms of analyzing its main development stages. They provide an assessment of listeners’ high confidence in radio broadcasts as compared to other mass media sources. Focus is placed on promoting sonic brands in the sphere of mediacommunication. The researchers also pay special attention to podcasting as a new way to listen to audio-content. The advantages and possible consequences of podcasting influence on radio-industry are assesse

Evidence of a dibaryon spectrum in coherent π0π0d photoproduction at forward deuteron angles

The coherent reaction, was studied with the BGOOD experiment at ELSA from threshold to a centre-of-mass energy of 2850 MeV. A full kinematic reconstruction was made, with final state deuterons identified in the forward spectrometer and decays in the central BGO Rugby Ball. The strength of the differential cross section exceeds what can be described by models of coherent photoproduction and instead supports the three isoscalar dibaryon candidates reported by the ELPH collaboration at 2.38, 2.47 and 2.63 GeV/c2. A low mass enhancement in the invariant mass is also observed at the ⁎ centre-of-mass energy which is consistent with the ABC effect. At higher centre-of-mass energies, a narrow peak in the invariant mass at 2114 MeV/c2 with a width of 20 MeV/c2 supports a sequential two-dibaryon decay mechanism

Photoproduction of K+ Δ(1405) → K+ π0 Σ0 extending to forward angles and low momentum transfer

K+ Lambda (1405) photoproduction has been studied at the BGOOD experiment via the all neutral decay, Lambda(1405)-> Sigma0 Pi0. The unique BGOOD experimental setup allows both the cross section and invariant mass Lamba(1405) distribution (line shape) to be measured over a broad K+ polar angle range, extending to extreme forward K+ angles unattainable at previous experiments. Evidence is provided for the role of a triangle singularity driven by the N*(2030)⁎ resonance, which appears to contribute significantly to K+Lambda(1405) photoproduction. This is observed in the integrated cross section which was determined with unprecedented energy resolution and supported by the angular distributions. The measured line shape is also in agreement with the previous results of CLAS and ANKE, and is consistent with two poles derived in χPT based models

Measurement of the γ n → K0 0 differential cross section over the K∗ threshold

The differential cross section for the quasi-free photoproduction reaction gamma(n)-> K-0 Sigma(0) was measured at BGOOD at ELSA from threshold to a centre-of-mass energy of 2400 MeV. Close to threshold the results are consistent with existing data and are in agreement with partial wave analysis solutions over the full measured energy range, with a large coupling to the Delta(1900)1/2(-) evident. This is the first dataset covering the K* threshold region, where there are model predictions of dynamically generated vector meson-baryon resonance contributions

Observation of a cusp-like structure in the γp → K+Σ0 cross section at forward angles and low momentum transfer

The gamma+p->K+ + Sigma0 differential cross section at extremely forward angles was measured at the BGOOD experiment. A three-quarter drop in strength over a narrow range in energy and a strong dependence on the polar angle of the in the centre-of-mass of the reaction is observed at a centre-of-mass energy of 1900 MeV. Residing close to multiple open and hidden strangeness thresholds, the structure appears consistent with meson-baryon threshold effects which may contribute to the reaction mechanism