Correlación entre el clima organizacional y desempeño en los trabajadores del Restaurant Sabor Cajabambino 2017

La presente investigación titulada "Correlación entre el clima organizacional y desempeño en los trabajadores del Restaurant Sabor Cajabambino 2017",Tuvo por objetivo determinar en qué medida influye el clima organizacional y desempeño de los trabajadores del restaurant Sabor Cajabambino; lo cual, me conllevó a crear la hipótesis. Si existe correlación significativa entre el clima organizacional y el desempeño en los trabajadores del restaurant Sabor Cajabambino. Los resultados obtenidos en la presente investigación coadyuvan a los trabajadores a tener un buen clima organizacional y desempeño y dar un mejor enfoque cordial a los trabajadores que son los que sirven al restaurant. La investigación fue aplicativa, de tipo descriptivo y diseño descriptivo, se aplicó como técnicas la encuesta y la observación directa y como instrumento el cuestionario, la población estuvo conformada por 15 trabajadores del restaurant Sabor Cajabambino. La investigación beneficia a los trabajadores, estudiantes, profesionales, investigadores científicos y a nuestro Pais.Tesi

Sequencing and Analysis of Lumpy Skin Disease Virus Whole Genomes Reveals a New Viral Subgroup in West and Central Africa

Lumpy skin disease virus (LSDV) is a member of the capripoxvirus (CPPV) genus of the Poxviridae family. LSDV is a rapidly emerging, high-consequence pathogen of cattle, recently spreading from Africa and the Middle East into Europe and Asia. We have sequenced the whole genome of historical LSDV isolates from the Pirbright Institute virus archive, and field isolates from recent disease outbreaks in Sri Lanka, Mongolia, Nigeria and Ethiopia. These genome sequences were compared to published genomes and classified into different subgroups. Two subgroups contained vaccine or vaccine-like samples ("Neethling-like" clade 1.1 and "Kenya-like" subgroup, clade 1.2.2). One subgroup was associated with outbreaks of LSD in the Middle East/Europe (clade 1.2.1) and a previously unreported subgroup originated from cases of LSD in west and central Africa (clade 1.2.3). Isolates were also identified that contained a mix of genes from both wildtype and vaccine samples (vaccine-like recombinants, grouped in clade 2). Whole genome sequencing and analysis of LSDV strains isolated from different regions of Africa, Europe and Asia have provided new knowledge of the drivers of LSDV emergence, and will inform future disease control strategies.</p

Omecamtiv mecarbil in chronic heart failure with reduced ejection fraction, GALACTIC‐HF: baseline characteristics and comparison with contemporary clinical trials

Aims: The safety and efficacy of the novel selective cardiac myosin activator, omecamtiv mecarbil, in patients with heart failure with reduced ejection fraction (HFrEF) is tested in the Global Approach to Lowering Adverse Cardiac outcomes Through Improving Contractility in Heart Failure (GALACTIC‐HF) trial. Here we describe the baseline characteristics of participants in GALACTIC‐HF and how these compare with other contemporary trials. Methods and Results: Adults with established HFrEF, New York Heart Association functional class (NYHA) ≥ II, EF ≤35%, elevated natriuretic peptides and either current hospitalization for HF or history of hospitalization/ emergency department visit for HF within a year were randomized to either placebo or omecamtiv mecarbil (pharmacokinetic‐guided dosing: 25, 37.5 or 50 mg bid). 8256 patients [male (79%), non‐white (22%), mean age 65 years] were enrolled with a mean EF 27%, ischemic etiology in 54%, NYHA II 53% and III/IV 47%, and median NT‐proBNP 1971 pg/mL. HF therapies at baseline were among the most effectively employed in contemporary HF trials. GALACTIC‐HF randomized patients representative of recent HF registries and trials with substantial numbers of patients also having characteristics understudied in previous trials including more from North America (n = 1386), enrolled as inpatients (n = 2084), systolic blood pressure &lt; 100 mmHg (n = 1127), estimated glomerular filtration rate &lt; 30 mL/min/1.73 m2 (n = 528), and treated with sacubitril‐valsartan at baseline (n = 1594). Conclusions: GALACTIC‐HF enrolled a well‐treated, high‐risk population from both inpatient and outpatient settings, which will provide a definitive evaluation of the efficacy and safety of this novel therapy, as well as informing its potential future implementation

Correlación entre el clima organizacional y desempeño en los trabajadores del Restaurant Sabor Cajabambino 2017

TesisLa presente investigación titulada "Correlación entre el clima organizacional y desempeño en los trabajadores del Restaurant Sabor Cajabambino 2017",Tuvo por objetivo determinar en qué medida influye el clima organizacional y desempeño de los trabajadores del restaurant Sabor Cajabambino; lo cual, me conllevó a crear la hipótesis. Si existe correlación significativa entre el clima organizacional y el desempeño en los trabajadores del restaurant Sabor Cajabambino. Los resultados obtenidos en la presente investigación coadyuvan a los trabajadores a tener un buen clima organizacional y desempeño y dar un mejor enfoque cordial a los trabajadores que son los que sirven al restaurant. La investigación fue aplicativa, de tipo descriptivo y diseño descriptivo, se aplicó como técnicas la encuesta y la observación directa y como instrumento el cuestionario, la población estuvo conformada por 15 trabajadores del restaurant Sabor Cajabambino. La investigación beneficia a los trabajadores, estudiantes, profesionales, investigadores científicos y a nuestro Pais

Funcionalidad familiar, desregulación emocional y agresividad en adolescentes de una institución educativa estatal de Trujillo

El estudio se orientó a determinar la relación entre Funcionalidad familiar, Desregulación emocional y agresividad en adolescentes de una institución educativa estatal de Trujillo. La investigación es de tipo básica, con diseño correlacional, siendo ejecutada considerando una muestra de 400 estudiantes entre el 3er, 4to y 5to grado de secundaria. Para la recolección de datos se contempló el cuestionario de regulación emocional, la escala de adaptabilidad familiar y el cuestionario de agresividad de Buss y Perry. Los resultados demostraron que la agresividad guarda relación directa con un tamaño de efecto moderado con la desregulación emocional (rho = .557). De esta forma se concluye que, existe relación entre la agresividad y la desregulación emociona. Además, no se observa relación entre la funcionalidad familiar y la desregulación emocional

Prevalence of chronic kidney disease of non-traditional causes in patients on hemodialysis in southwest Guatemala

ABSTRACT Objective To document the prevalence of patients on hemodialysis in southwestern Guatemala who have chronic kidney disease (CKD) of non-traditional causes (CKDnt). Methods This cross-sectional descriptive study interviewed patients on hemodialysis at the Instituto Guatemalteco de Seguridad Social on their health and occupational history. Laboratory serum, urine and vital sign data at the initiation of hemodialysis were obtained from chart reviews. Patients were classified according to whether they had hypertension or obesity or neither. The proportion of patients with and without these traditional CKD risk factors was recorded and the association between demographic and occupational factors and a lack of traditional CKD risk factors analyzed using multivariate logistic regression. Results Of 242 total patients (including 171 non-diabetics) enrolled in hemodialysis in southwestern Guatemala, 45 (18.6% of total patients and 26.3% of non-diabetics) lacked traditional CKD risk factors. While agricultural work history was common, only travel time greater than 30 minutes and age less than 50 years old were significantly associated with CKD in the absence of traditional risk factors. Individuals without such risk factors lived throughout southwestern Guatemala’s five departments. Conclusions The prevalence of CKDnT appears to be much lower in this sample of patients receiving hemodialysis in Southwestern Guatemala than in hospitalized patients in El Salvador. It has yet to be determined whether the prevalence is higher in the general population and in patients on peritoneal dialysis

A One Health Approach to Investigating <i>Leptospira</i> Serogroups and Their Spatial Distributions among Humans and Animals in Rio Grande do Sul, Brazil, 2013–2015

Leptospirosis is an endemic zoonotic disease in Brazil and is widespread throughout rural populations in the state of Rio Grande do Sul. This study aimed to identify presumptive infecting Leptospira serogroups in human and animal cases and describe their occurrences within the ecoregions of the state by animal species. Data for human and animal leptospirosis cases were gathered from the government&#8217;s passive surveillance systems and presumptive infecting serogroups were identified based on a two-fold titer difference in serogroups in the microscopic agglutination test (MAT) panel. A total of 22 different serogroups were reported across both human and animal cases. Serogroup Icterohaemorrhagiae was the most common among humans, while serogroup Sejroe predominated among animal cases, particularly bovines. Each ecoregion had a large distribution of cases, with 51% of the human cases in the Parana&#8315;Paraiba ecoregion, and 81% of the animal cases in the Savannah ecoregion. Identifying and mapping the serogroups circulating using the One Health approach is the first step for further understanding the distribution of the disease in the state. This study has the potential to aid in guiding public health and agricultural practices, furthering the need for a human vaccine in high-risk populations to complement control and prevention efforts

Diagnostic ability of inner macular layers to discriminate early glaucomatous eyes using vertical and horizontal B-scan posterior pole protocols.

PURPOSE:To evaluate the diagnostic ability of macular ganglion cell (mGCL) and macular retinal nerve fiber (mRNFL) layers, to detect early glaucomatous eyes, using the new segmentation software of Spectralis optical coherence tomography (OCT) device (Heidelberg Engineering). METHODS:A total of 83 eyes from 83 subjects were included in this observational, prospective cross-sectional study: 43 healthy controls and 40 early primary open-angle glaucoma (POAG) patients. All participants were examined using the Horizontal and Vertical Posterior Pole protocols, and the peripapillary RNFL (pRNFL) protocol of Spectralis OCT device. The new automated retinal segmentation software was applied to horizontal and vertical macular B-scans to determine mGCL and mRNFL thicknesses in each one of the 9 sectors of the Early Treatment Diagnostic Retinopathy Study circle. Thickness of each layer was compared between groups, and the sectors with better area under the receiver operating characteristic curve (AUC) were identified. RESULTS:mGCL was significantly thinner in the POAG group, especially in outer and inner temporal sectors (p<0.001); and mRNFL was significantly thinner in the POAG group in the outer inferior and the outer superior sector (p<0.001). Diagnostic accuracy of inner macular layers was good, and in general mGCL was superior to mRNFL. pRNFL obtained the best diagnostic capability (AUC, 0.886). Horizontal and vertical Posterior Pole protocols performed similarly. CONCLUSIONS:Inner macular layers using either horizontal or vertical B-scans, especially temporal sectors of mGCL, have good diagnostic capability to differentiate early glaucomatous eyes from control eyes; however, pRNFL has the highest diagnostic sensitivity for glaucoma detection