Association of subsequent survival with quality of life Physical Component Summary (PCS) and Mental Component Summary (MCS) score assessed approximately 5 years after colorectal cancer diagnosis.

<p>Association of subsequent survival with quality of life Physical Component Summary (PCS) and Mental Component Summary (MCS) score assessed approximately 5 years after colorectal cancer diagnosis.</p

Association of personal characteristics at enrollment with mean Physical Component Summary (PCS) and Mental Component Summary (MCS) scores from the VR-12, for survivors at 5 year follow-up in the Seattle Colorectal Cancer Family Registry.

<p>Association of personal characteristics at enrollment with mean Physical Component Summary (PCS) and Mental Component Summary (MCS) scores from the VR-12, for survivors at 5 year follow-up in the Seattle Colorectal Cancer Family Registry.</p

Kaplan-Meier survival curves comparing survivors by Physical Component Summary (PCS) and Mental Component Summary (MCS) scores.

<p>Kaplan-Meier survival curves comparing survivors by Physical Component Summary (PCS) and Mental Component Summary (MCS) scores.</p

Associations of survivor personal characteristics with VR-12 Physical Component Summary (PCS) or Mental Component Summary (MCS) score below 10^th percentile value in the general population, among CRC survivors approximately 5 years after diagnosis, Seattle Colon Cancer Family Registry (enrolled 1998–2004).

<p>Associations of survivor personal characteristics with VR-12 Physical Component Summary (PCS) or Mental Component Summary (MCS) score below 10^th percentile value in the general population, among CRC survivors approximately 5 years after diagnosis, Seattle Colon Cancer Family Registry (enrolled 1998–2004).</p

Odds ratios (ORs) and 95% confidence intervals (CIs) for the associations of individual miRNA expression levels with colorectal neoplasia.

a<p>Compared to controls, adjusted for age and sex.</p>b<p>OR per log₁₀ unit.</p>c<p>OR comparing detected to non-detected.</p><p>Odds ratios (ORs) and 95% confidence intervals (CIs) for the associations of individual miRNA expression levels with colorectal neoplasia.</p

Pairwise Pearson correlation coefficients (R) between miRNAs among controls (N = 48), independent of age and sex.

a<p>Parameterized as detected or not detected.</p><p>Test of null hypothesis that R = 0:</p><p>*P<0.0001.</p>†<p>0.0001‡</p><p>0.001§</p><p>0.01</p><p>Pairwise Pearson correlation coefficients (R) between miRNAs among controls (N = 48), independent of age and sex.</p

Area under the curve (AUC) with 95% confidence intervals (CIs) from receiver operating characteristic analysis measuring the ability of miRNA expression levels to discriminate between controls and each case group.

a<p>Discriminating from controls.</p>b<p>AUC based on classification by detection or non-detection.</p><p>Area under the curve (AUC) with 95% confidence intervals (CIs) from receiver operating characteristic analysis measuring the ability of miRNA expression levels to discriminate between controls and each case group.</p

Selected characteristics of cases and sibling controls from participants in the Colon Cancer Family Registry.

1<p>Non-Hispanic white family-based discordant siblings with age and sex data. ²Self-reported weight and height 2 years prior to questionnaire completion date used to calculate body mass index (BMI). ³Average weekly total lifetime MET hours. ⁴Estimated from 1-df likelihood ratio test from a conditional logistic regression model.</p

<i>SMAD7</i> tagging SNPs and colorectal cancer risk in the Colon Cancer Family Registry.

1<p>Minor allele frequencies (MAFs) were estimated using unrelated population-based controls. ²Results were estimated using a log-additive model, adjusted for age and sex.</p

SNP rs12953713 and rs11874392 by tumor characteristics among population-based families.

1<p>Adjusted for age and sex. ²P for interaction was estimated from 2 degrees of freedom likelihood-ratio test of the interaction term between the tumor characteristics and SNP rs12953713.</p