Etching of aluminum for bonding Patent

Etching aluminum alloys with aqueous solution containing sulfuric acid, hydrofluoric acid, and an alkali metal dischromate for adhesive bondin

VLBI Polarimetry of 177 Sources from the Caltech-Jodrell Bank Flat-spectrum Survey

We present VLBA observations and a statistical analysis of 5 GHz VLBI polarimetry data from 177 sources in the Caltech-Jodrell Bank flat-spectrum (CJF) survey. The CJF survey, a complete, flux-density-limited sample of 293 extragalactic radio sources, gives us the unique opportunity to compare a broad range of source properties for quasars, galaxies and BL Lacertae objects. We focus primarily on jet properties, specifically the correlation between the jet axis angle and the polarization angle in the core and jet. A strong correlation is found for the electric vector polarization angle in the cores of quasars to be perpendicular to the jet axis. Contrary to previous claims, no correlation is found between the jet polarization angle and the jet axis in either quasars or BL Lac objects. With this large, homogeneous sample we are also able to investigate cosmological issues and AGN evolution.Comment: Accepted to the Astrophysical Journal: 37 pages, 14 figure

High-concentration Er:YAG single-crystal fibers grown by laser-heated pedestal growth technique

High-concentration Er:YAG single-crystal fibers have been grown using the laser-heated pedestal growth technique. Instability in the melt and concomitant opacity of fibers were observed at source concentrations higher than 15 mol.%. Spectroscopic examination shows that broadening of the linewidth of the I<sub>13/2</sub>4→I<sub>15/2</sub>4 transition is strongly dependent on Er<sup>3+</sup> concentration

Stratospheric aerosol modification by supersonic transport operations with climate implications

The potential effects on stratospheric aerosois of supersonic transport emissions of sulfur dioxide gas and submicron size soot granules are estimated. An interactive particle-gas model of the stratospheric aerosol is used to compute particle changes due to exhaust emissions, and an accurate radiation transport model is used to compute the attendant surface temperature changes. It is shown that a fleet of several hundred supersonic aircraft, operating daily at 20 km, could produce about a 20% increase in the concentration of large particles in the stratosphere. Aerosol increases of this magnitude would reduce the global surface temperature by less than 0.01 K

An Analysis of Neptune's Stratospheric Haze Using High-Phase-Angle Voyager Images

We have inverted high-phase-angle Voyager images of Neptune to determine the atmospheric extinction coefficient as a function of altitude and the scattering phase function at a reference altitude. Comparisons between theoretical model and observations help separate the contributions from molecular Rayleigh and aerosol scattering and help determine the variation of the aerosol size, concentration, and scattering properties with altitude. Further comparisons between models and data allow us to place constraints on the location and composition of the hazes, the concentration and downward flux of certain condensible hydrocarbon gases, the eddy diffusion coefficient in the lower stratosphere, and the thermal profile in parts of Neptune's stratosphere. We find that a distinct stratospheric haze layer exists near 12(sub -1, sup +1) mbar in Neptune's lower stratosphere, most probably due to condensed ethane. The derived stratospheric haze production rate of 1.0(sub -0.3, sup +0.2) x 10(exp -15) g cm(exp -2) sec(exp -1) is substantially lower than photochemical model predictions. Evidence for hazes at higher altitudes also exists. Unlike the situation on Uranus, large particles (0.08-0.11 microns) may be present at high altitudes on Neptune (e.g., near 0.5 mbar), well above the region in which we expect the major hydrocarbon species to condense. Near 28 mbar, the mean particle size is about 0.13(sub -0.02, sup +0.02) microns with a concentration of 5(sub -3, sup +3) particles cm(exp -3). The cumulative haze extinction optical depth above 15 mbar in the clear filter is approx. 3 x 10(exp -3), and much of this extinction is due to scattering rather than absorption; thus, if our limb-scan sites are typical, the hazes cannot account for the stratospheric temperature inversion on Neptune and may not contribute significantly to atmospheric heating. We compare the imaging results with the results from other observations, including those of the Voyager Photopolarimeter Subsystem, and discuss differences between Neptune and Uranus

Carbon Free Boston: Technical Summary

Part of a series of reports that includes: Carbon Free Boston: Summary Report; Carbon Free Boston: Social Equity Report; Carbon Free Boston: Buildings Technical Report; Carbon Free Boston: Transportation Technical Report; Carbon Free Boston: Waste Technical Report; Carbon Free Boston: Energy Technical Report; Carbon Free Boston: Offsets Technical Report; Available at http://sites.bu.edu/cfb/OVERVIEW: This technical summary is intended to argument the rest of the Carbon Free Boston technical reports that seek to achieve this goal of deep mitigation. This document provides below: a rationale for carbon neutrality, a high level description of Carbon Free Boston’s analytical approach; a summary of crosssector strategies; a high level analysis of air quality impacts; and, a brief analysis of off-road and street light emissions.Published versio

Antibody-Based Ticagrelor Reversal Agent in Healthy Volunteers.

BACKGROUND: Ticagrelor is an oral P2Y12 inhibitor that is used with aspirin to reduce the risk of ischemic events among patients with acute coronary syndromes or previous myocardial infarction. Spontaneous major bleeding and bleeding associated with urgent invasive procedures are concerns with ticagrelor, as with other antiplatelet drugs. The antiplatelet effects of ticagrelor cannot be reversed with platelet transfusion. A rapid-acting reversal agent would be useful. METHODS: In this randomized, double-blind, placebo-controlled, phase 1 trial, we evaluated intravenous PB2452, a monoclonal antibody fragment that binds ticagrelor with high affinity, as a ticagrelor reversal agent. We assessed platelet function in healthy volunteers before and after 48 hours of ticagrelor pretreatment and again after the administration of PB2452 or placebo. Platelet function was assessed with the use of light transmission aggregometry, a point-of-care P2Y12 platelet-reactivity test, and a vasodilator-stimulated phosphoprotein assay. RESULTS: Of the 64 volunteers who underwent randomization, 48 were assigned to receive PB2452 and 16 to receive placebo. After 48 hours of ticagrelor pretreatment, platelet aggregation was suppressed by approximately 80%. PB2452 administered as an initial intravenous bolus followed by a prolonged infusion (8, 12, or 16 hours) was associated with a significantly greater increase in platelet function than placebo, as measured by multiple assays. Ticagrelor reversal occurred within 5 minutes after the initiation of PB2452 and was sustained for more than 20 hours (P\u3c0.001 after Bonferroni adjustment across all time points for all assays). There was no evidence of a rebound in platelet activity after drug cessation. Adverse events related to the trial drug were limited mainly to issues involving the infusion site. CONCLUSIONS: In healthy volunteers, the administration of PB2452, a specific reversal agent for ticagrelor, provided immediate and sustained reversal of the antiplatelet effects of ticagrelor, as measured by multiple assays. (Funded by PhaseBio Pharmaceuticals; ClinicalTrials.gov number, NCT03492385.)

The Advancing Justice Through DNA Technology Act of 2003 (H.R. 3214): A Section-by-Section Analysis

This report summarizes the Advancing Justice Through DNA Technology Act (H.R. 3214). Additionally, the report covers each title of the act such as title one expanding the ability to qualify for the DNA Backlog Grant Program