721 research outputs found

    Assessing the costs and benefits of agricultural production using an ecosystem approach

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    Integrated Farm Management (IFM) is seen as one way for agriculture to contribute towards the UKs challenging national targets for climate change, pollution, biodiversity and other environmental factors. Whilst it is clear that IFM and associated assurance schemes have a role in food quality and enhancement of the environment, they fail to address a number of issues. In particular, they fail to take sufficient account of ‘impact’ and ‘outcome’. In contrast, the relatively new concept of an ecosystem approach does consider these and there is extensive synergy between this approach and IFM. This is pertinent because the UK Department for the Environment, Food and Rural Affairs (Defra) is taking steps to embed an ecosystem approach in policy-making and delivery. This paper sets out to explore the links between IFM and an ecosystem approach and introduces a simple matrix to show how an ecosystem approach might be used to assess the outcome of IFM practices. Limited use of an ecosystem approach suggests that this type of methodology could deliver useful results for IFM. However, it should be used as a decision-support tool rather than a decision-maker. The advantage of using an ecosystem approach for assessing the impact of IFM is that it provides a holistic assessment of land management strategies, rather than focusing on either cropping, or environmental management, alone. However, the values assigned to individual parameters are generally based on expert opinion and, as such, are open to interpretation. Indeed, an ecosystem approach should be interdisciplinary, utilising the knowledge and expertise of a range of stakeholders. Whilst the development of an ecosystem approach for use within an agricultural setting shows promise, it is still in its infancy. There is a need for much discussion, between many disciplines, before it becomes accepted practice

    Picture this: researching child workers

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    Visual methods such as photography are under-used in the active process of sociological research. As rare as visual methods are, it is even rarer for the resultant images to be made by rather than of research participants. Primarily, the paper explores the challenges and contradictions of using photography within a multi-method approach. We consider processes for analysing visual data, different ways of utilising visual methods in sociological research, and the use of primary and secondary data, or, simple illustration versus active visual exploration of the social. The question of triangulation of visual data against text and testimony versus a stand-alone approach is explored in depth

    Integrated Optics: a Report on the 2nd OSA Topical Meeting

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    This report surveys the papers presented at the 2nd OSA Topical Meeting on Integrated Optics, which was held 21–24 January 1974 in New Orleans, La

    Using Psychodynamic, Cognitive Behavioral, and Control Mastery Prototypes to Predict Change: A New Look at an Old Paradigm for Long-Term Single-Case Research

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    This article illustrates a method of testing models of change in individual long-term psychotherapy cases. A depressed client was treated with 208 sessions of control mastery therapy (CMT), an unmanualized approach that integrates elements of psychodynamic therapy (PDT) and cognitive behavioral therapy (CBT). Panels of experts developed prototypes of ideal PDT, CBT, and CMT process using the Psychotherapy Process Q-set (PQS; J. S. Ablon & E. E. Jones, 1999; E. E. Jones, L. A. Parke, & S. Pulos, 1992; E. E. Jones & S. M. Pulos, 1993). Independent observers rated every 4th session (N = 53) with the PQS. Using correlations between ideal and actual PQS ratings followed by paired t tests, the authors compared adherence to the CMT prototype with adherence to plausible alternative models advocated by the PDT and CBT experts. Bivariate time series analyses determined whether prototype adherence predicted an estimated index of symptom change. Results showed that the therapist\u27s behavior was most consistent with the CMT prototype and that this aspect of the CMT prototype along with particular aspects of the other prototypes influenced estimated symptom change. The results, which replicate and extend earlier findings, support the validity of this approach to studying long-term therapies but also highlight its limitations

    Pendampingan Masyarakat Dalam Pengolahan Limbah Organik di Desa Samkai Kecamatan Merauke

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    Kegiatan pendampingan berupa pengolahan sampah organik berupa sampah rumah tangga menjadi kompos sebagai pupuk dilaksanakan karena banyaknya limbah rumah tangga yang dihasilkan warga dan berdampak pada pencemaran lingkungan. Kegiatan ini melibatkan pihak pemerintah desa khususnya organisasi PKK dan Dinas Lingkungan Hidup Kabupaten Merauke. Tahapan kegiatan yang dilakukan ada tiga yaitu pembuatan komposter, sosialisasi dan demonstrasi pembuatan kompos oleh Dinas Lingkungan Hidup dan dosen ahli, dan pendampingan pemanfaatan kompos untuk tanaman di pekarangan. Sasaran program ini adalah warga di Kelurahan Samkai khususnya anggota PKK sejumlah 20 orang. Pengukuran ketercapaian program adalah dengan menggunakan instrumen pengamatan dan wawancara ke mitra. Hasil dari kegiatan ini adalah sebanyak 75% warga memperoleh peningkatan pengetahuan dalam membuat kompos dan sebanyak 56% warga memperoleh peningkatan pengetahuan dalam memanfaatkan kompos sebagai pupuk tanaman pekarangan. Potensi keberlanjutan program ini adalah diharapkan warga akan melakukan pembiasaan dalam memanfaatkan limbah untuk diolah menjadi pupuk yang dapat dimanfaatkan secara langsung

    Prospective Prediction of Posttraumatic Stress Disorder Symptoms Using Fear Potentiated Auditory Startle Responses

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    Background: Posttraumatic stress disorder (PTSD) has been most consistently associated with exaggerated physiologic reactivity to startling sounds when such sounds occur in threatening contexts. There is conflicting evidence about whether startle hyperreactivity is a preexisting vulnerability factor for PTSD or an acquired result of posttrauma neural sensitization. Until now, there have been no prospective studies of physiologic reactivity to startling sounds in threatening contexts as predictors of PTSD symptoms. Methods: One hundred and thirty-eight police academy cadets without current psychopathology were exposed to repeated 106-dB startling sounds under increasing (low, medium, or high) threat of mild electric shock while their eye-blink electromyogram, skin conductance, heart rate, and subjective fear responses were recorded. Measures of response habituation were also calculated. Following 1 year of exposure to police-related trauma, these participants were assessed for PTSD symptom severity. Results: After accounting for other baseline variables that were predictive of PTSD symptom severity (age and general psychiatric distress), more severe PTSD symptoms were prospectively and independently predicted by the following startle measures: greater subjective fear under low threat, greater skin conductance under high threat, and slower skin conductance habituation. Conclusions: These results imply that hypersensitivity to contextual threat (indexed by greater fear under low threat), elevated sympathetic nervous system reactivity to explicit threat (indexed by larger responses under high threat), and failure to adapt to repeated aversive stimuli (evidenced by slower habituation) are all unique preexisting vulnerability factors for greater PTSD symptom severity following traumatic stress exposure. These measures may eventually prove useful for preventing PTSD

    Farmers’ management of functional biodiversity goes beyond pest management in organic European apple orchards

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    Supporting functional biodiversity (FB), which provides natural pest regulation, is an environmentally sound and promising approach to reduce pesticide use in perennial cultures such as apple, especially in organic farming. However, little is known about farmers’ practices and motivations to implement techniques that favor FB, especially whether or not they really expect anything from FB in terms of pest regulation. In fact, FB-supporting techniques (FB-techniques) are massively questioned by practitioners due to inadequate information about their effectiveness. An interview survey was performed in eight European countries(i) to describe farmers’ practices and identify promising FB-techniques: (ii) to better understand their perceptions of and values associated with FB; and (iii) to identify potential drivers of (non-)adoption. Fifty-five advisors and 125 orchard managers with various degrees of experience and convictions about FB were interviewed and a total of 24 different FB-techniques which can be assigned to three different categories (ecological infrastructures, farming practices and redesign techniques) were described. Some were well-established measures (e.g., hedges and bird houses), while others were more marginal and more recent (e.g., animal introduction and compost). On average, farmers combined more than four techniques that had been implemented over a period of 13 years, especially during their establishment or conversion period. In general, it was difficult for farmers to evaluate the effectiveness of individual FB-techniques on pest regulation. They considered FB-techniques as a whole, targeting multiple species, and valued multiple ecosystem services in addition to pest regulation. The techniques implemented and their associated values differed among farmers who adopted various approaches towards FB. Three different approaches were defined: passive, active and integrated. Their appraisal of FB is even more complex because it may change with time and experience. These findings provide empirical evidence that the practical implementation of promising techniques remains a challenge, considering the diversity of situations and evaluation criteria. Increased cooperation between researchers, farmers and advisors should more effectively target research, advisory support and communication to meet farmers’ needs and perceptions

    PMC42, a breast progenitor cancer cell line, has normal-like mRNA and microRNA transcriptomes.

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    INTRODUCTION: The use of cultured cell lines as model systems for normal tissue is limited by the molecular alterations accompanying the immortalisation process, including changes in the mRNA and microRNA (miRNA) repertoire. Therefore, identification of cell lines with normal-like expression profiles is of paramount importance in studies of normal gene regulation. METHODS: The mRNA and miRNA expression profiles of several breast cell lines of cancerous or normal origin were measured using printed slide arrays, Luminex bead arrays, and real-time reverse transcription-polymerase chain reaction. RESULTS: We demonstrate that the mRNA expression profiles of two breast cell lines are similar to that of normal breast tissue: HB4a, immortalised normal breast epithelium, and PMC42, a breast cancer cell line that retains progenitor pluripotency allowing in-culture differentiation to both secretory and myoepithelial fates. In contrast, only PMC42 exhibits a normal-like miRNA expression profile. We identified a group of miRNAs that are highly expressed in normal breast tissue and PMC42 but are lost in all other cancerous and normal-origin breast cell lines and observed a similar loss in immortalised lymphoblastoid cell lines compared with healthy uncultured B cells. Moreover, like tumour suppressor genes, these miRNAs are lost in a variety of tumours. We show that the mechanism leading to the loss of these miRNAs in breast cancer cell lines has genomic, transcriptional, and post-transcriptional components. CONCLUSION: We propose that, despite its neoplastic origin, PMC42 is an excellent molecular model for normal breast epithelium, providing a unique tool to study breast differentiation and the function of key miRNAs that are typically lost in cancer.RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'. In brief you may : copy, distribute, and display the work; make derivative works; or make commercial use of the work - under the following conditions: the original author must be given credit; for any reuse or distribution, it must be made clear to others what the license terms of this work are
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