Corrosion-electrochemical behavior of nickel in an alkali metal carbonate melt under a chlorine-containing atmosphere

The corrosion-electrochemical behavior of a nickel electrode is studied in the melt of lithium, sodium, and potassium (40: 30: 30 mol %) carbonates in the temperature range 500-600°C under an oxidizing atmosphere CO2 + 0.5O2 (2: 1), which is partly replaced by gaseous chlorine (30, 50, 70%) in some experiments. In other experiments, up to 5 wt % chloride of sodium peroxide is introduced in a salt melt. A change in the gas-phase composition is shown to affect the mechanism of nickel corrosion. © 2013 Pleiades Publishing, Ltd

Comparative pharmacology of a new recombinant FSH expressed by a human cell line

Recombinant FSH proteins are important therapeutic agents for the treatment of infertility, including follitropin alfa expressed in Chinese Hamster Ovary (CHO) cells and, more recently, follitropin delta expressed in the human cell line PER.C6. These recombinant FSH proteins have distinct glycosylation, and have distinct pharmacokinetic and pharmacodynamic profiles in women. Comparative experiments demonstrated that follitropin delta and follitropin alfa displayed the same in vitro potency at the human FSH receptor, but varied in their pharmacokinetics in mouse and rat. While follitropin delta clearance from serum depended in part on the hepatic asialoglycoprotein receptor (ASGPR), follitropin alfa clearance was unaffected by ASGPR inhibition in rat or genetic ablation in mice. The distinct properties of follitropin delta and follitropin alfa are likely to contribute to the differing pharmacokinetic and pharmacodynamic profiles observed in women and to influence their efficacy in therapeutic protocols for the treatment of infertility

On the solution of a control problem for the motion of an object in the dense layers of the atmosphere

The paper deals with the construction of algorithms for solving an optimal control problem for a nonlinear dynamic system in the presence of phase constraints. The system under consideration describes the motion of a controlled object as a rigid body in the dense layers of the atmosphere under the gravitational and aerodynamic forces. The desired control must minimize a terminal performance index under a number of constraints on the control and the phase state of the dynamic system. The performance index characterizes the accuracy of bringing the center of mass of the object to a given set with a required direction of its velocity. The control is carried out by changing the spatial orientation of movable control elements of the object structure. A time-iterative procedure is proposed for the construction of admissible controls. The procedure is based on the sequential use of the aerodynamic force acting on the controlling elements, which provides the desired direction of the velocity vector of the center of mass under all the constraints. To determine the required moment, it is proposed to use a relation that connects it with the moment of the aerodynamic force acting on the remaining surface of the object with the desired direction of the velocity vector. For this moment, the values of the control parameters that implement it are calculated. The efficiency of the proposed algorithm for constructing admissible controls is illustrated by a model example of an applied optimal control problem. In this problem, the dynamic system describes the motion of a stage of a launch vehicle (recoverable block) in the atmospheric section of its trajectory, where the block moves to a specified landing area. The results of numerical simulation are presented. © 2021 Krasovskii Institute of Mathematics and Mechanics. All rights reserved

Результаты исследования продуктивности откормочных свиней в технологическом модуле

Due to the high intensity and profitability of production, pig breeding is an engaging activity for both large agricultural enterprises and farms. Today, however, all the production growth comes from large pig farms and complexes. The share of small-scale farms decreases annually due to the need for modern scienceintensive technical and technological planning solutions that reduce labor costs and maximize the use of animal genetic potential. To solve this problem, the authors have developed a project and manufactured a prototype of a technological module for fattening pigs. The fattening period of pigs was 100 days from the age of three months. Studies showed that average daily gains ranged from 520 to 906 g and feed conversion ratio from 3.05 to 3.6 depending on the year. The consumption of water, electricity, and labor required for animals to gain 1 kg of live weight varied in the range of 6.54-8.25 liters/kg, 0.028-0.069 kWh/kg, and 0.031-0.064 person-hours/kg, respectively. The content of harmful gases such as CO2, NH3, and H2S generally complied with the maximum permissible concentrations, except for some time intervals during the cold season, so it was proposed to install an additional forced air extraction system during this period. The effectiveness of using the developed technological module on small-scale commercial enterprises, based on the obtained technical and economic indicators, is comparable to the hands of large pig farms.Ввиду высокой интенсивности и рентабельности производства свиноводство является привлекательным видом деятельности как для крупных сельскохозяйственных предприятий, так и для фермерских хозяйств. Однако на сегодняшний день весь рост производства приходится на крупные свинофермы и комплексы. Доля мелкотоварных предприятий ежегодно сокращается ввиду отсутствия современных наукоемких технико-технологических и планировочных решений, обеспечивающих снижение трудозатрат и максимальное использование генетического потенциала животных. Для решения обозначенной проблемы авторами статьи был разработан проект и изготовлен опытный образец технологического модуля для откорма свиней. Срок откорма свиней составлял 100 дней с трехмесячного возраста. Исследования показали, что среднесуточные приросты варьировали от 520 до 906 г, а коэффициент конверсии корма – от 3,05 до 3,6 в зависимости от периода года. Затраты воды, электроэнергии и труда, необходимые для набора животными 1 кг живой массы, изменялись в диапазонах 6,54–8,25 л/кг, 0,028–0,069 кВт·ч/кг и 0,031-0,064 чел.-ч/кг соответственно. Содержание вредных газов таких как СО2, NH3, H2S, в целом соответствовало предельно допустимым концентрациям, за исключением некоторых временных промежутков в холодное время года, поэтому была предложена установка дополнительной принудительной системы отвода воздуха в данный период. Эффективность использования разработанного технологического модуля на мелкотоварных предприятиях, исходя из полученных технико-экономических показателей, сопоставима с показателями крупных свиноводческих предприятий

Densification, morphological and transport properties of functional La1–xBaxYbO3– δ ceramic materials

The effective operation of protonic ceramic electrochemical cells requires the design of electrolytes having not only high ionic conductivity, but also excellent stability with respect to carbonisation. In the present work, the La-based oxides (La1–xBaxYbO3–δ, 0.03 ≤ x ≤ 0.10) are proposed as a possible alternative to the convenient Ba(Ce,Zr)O3-based electrolytes due to their high chemical stability. It was discovered that Ba-doping results in a deterioration of sintering behaviour; as a result, the relative density decreases and open porosity appears (for x = 0.10). A thorough analysis of transport properties by means of AC and DC measurement techniques enables a selection of the La0.97Ba0.03YbO3–δ sample, which demonstrates the highest conductivity compared with those samples where x = 0.5 and 0.10. Due to its excellent densification behaviour, stability and ionic conductivity, La0.97Ba0.03YbO3–δ can be considered as a promising proton-conducting electrolyte in the La-based family. © 2019 Elsevier Lt

Prognostic value of leukocyte indices in acute severe pancreatitis

The article analyzed the results of laboratory blood tests obtained in patients on the day of entry into the body and calculated for various leukocyte indices in patients with acute severe pancreatitis. The study based on the case reports of the MAI “City Clinical Hospital” No. 40 of Yekaterinburg in the period 2015-2020. The study aim is to identify the informative value of leukocyte indicators in relation to predicting the severity of acute pancreatitis and mortality. Some leukocyte indices have sufficient information in predicting the severity, course of acute pancreatitis and mortality, taking into account the incidence.В статье были проанализированы результаты лабораторных исследований крови, полученных у пациентов в день поступления в приемный покой и рассчитаны различные лейкоцитарные индексы у пациентов с острым тяжелым панкреатитом. Исследование проведено по материалам историй болезни МАУ «Городская клиническая больница» №40 г. Екатеринбурга в период 2015-2020 гг. Проведенное исследование было направлено на выявление информативности лейкоцитарных индексов в отношении прогнозирования тяжести течения острого панкреатита и летальности. Некоторые лейкоцитарные индексы обладают достаточной информативностью в прогнозировании тяжести течения острого панкреатита и летальности, связанной с данным заболеванием

Way of decreasing the level of endogenous intoxication syndrome in experimental pancreatonecrosis

The goal of the study lies in researching the possibility of influence of compound “L-17”, from the group of substituted 5R1,6H2-1,3,4-thiadiazine-2-amines, on the process of acute inflammation reaction in experimental pancreatic necrosis on the intensity of endogenous intoxication syndrome. An experimental model of pancreatic necrosis has been reproduced on rats. The results let us assert that the compound “L-17" has high efficiency when curing an experimental pancreatic necrosis. It has been proved by reduction of endointoxication.Цель работы заключалась в оценке возможности воздействия соединением «L-17» из группы замещённых 5R1, 6Н2-1,3,4-тиадиазин-2-аминов на выраженность синдрома эндогенной интоксикации при экспериментальном панкреонекрозе, воспроизведенном на крысах. Оценку уровня выраженности синдрома эндогенной интоксикации проводили на основе определения связывающей способности альбумина и концентрации веществ низкой и средней молекулярной массы в динамике эксперимента. Полученные в эксперименте результаты позволяют судить о высокой эффективности воздействия соединением «L-17» на снижение уровня эндогенной интоксикации

Correction of hemocoagulation abnormalities in experimental pancreatic necrosis

The goal of the study lies in researching the possibility of influence of compound “L-17", from the group of substituted 5R1,6H2-1,3,4-thiadiazine-2-amines, on the process of acute inflammation reaction in experimental pancreatic necrosis on the indices of hemocoagulation. An experimental model of pancreatic necrosis has been reproduced on rats. The results let us assert that the compound “L-17” has high efficiency when curing an experimental pancreatic necrosis. It has been proved by prevention of the progression of Disseminated Intravascular Coagulation syndrome.Цель работы заключалась в изучении воздействия соединения « И 7» из группы замещённых 5R116Н2-1,3,4-тиадиазин2-аминов на течение острой воспалительной реакции при экспериментальном панкреонекрозе по пока-зателям гемокоагуляции. Экспериментальная модель панкреонекроза воспроизведена на крысах. Полученные результаты позволяют судить о высокой эффективности соединения «L-17» при лечении экспериментального панкреонекроза, что подтверждается предупреждением развития ДВС-синдрома